Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313308905> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W4313308905 endingPage "610" @default.
- W4313308905 startingPage "601" @default.
- W4313308905 abstract "Abstract Recent studies have demonstrated that the basal core structure of the lipopolysaccharides of most Gram-negative bacilli are of similar or identical chemical structure. The current investigations evaluate the protective effect of immunization with these shared antigens against challenge with two heterologous Gram-negative bacilli, K. pneumoniae and E. coli 107. Active and passive immunization of mice with the Ra, Rb, Rc and Rd1 mutants of S. minnesota failed to protect against challenge with K. pneumoniae. In contrast, active and passive immunization with the Rd2 and Re mutants of S. minnesota afforded significant protection against challenge with K. pneumoniae. Similarly, active immunization with Re and passive immunization with Ra, Rc, Rd2 and Re provided significant protection against challenge with E. coli 107. In all instances, immunization with Re afforded greater protection than any of the other rough mutants of S. minnesota. Active immunization with the Re mutant was considerably less effective than type specific immunization. Immunization with Re increased the LD50 of E. coli 107 by 10-fold and K. pneumoniae by 100-fold over that of controls, while type specific immunization increased the LD50 to these organisms by greater than 100-fold and 10,000-fold respectively. The specificity of the protection induced was demonstrated by the loss of the protective activity of rabbit antiserum to Re after adsorption of the serum with dead Re mutants." @default.
- W4313308905 created "2023-01-06" @default.
- W4313308905 creator A5030847103 @default.
- W4313308905 creator A5050521463 @default.
- W4313308905 date "1972-03-01" @default.
- W4313308905 modified "2023-10-03" @default.
- W4313308905 title "Immunization with R Mutants of <i>S. Minnesota</i>" @default.
- W4313308905 doi "https://doi.org/10.4049/jimmunol.108.3.601" @default.
- W4313308905 hasPublicationYear "1972" @default.
- W4313308905 type Work @default.
- W4313308905 citedByCount "64" @default.
- W4313308905 countsByYear W43133089052023 @default.
- W4313308905 crossrefType "journal-article" @default.
- W4313308905 hasAuthorship W4313308905A5030847103 @default.
- W4313308905 hasAuthorship W4313308905A5050521463 @default.
- W4313308905 hasConcept C104317684 @default.
- W4313308905 hasConcept C143065580 @default.
- W4313308905 hasConcept C147483822 @default.
- W4313308905 hasConcept C159047783 @default.
- W4313308905 hasConcept C203014093 @default.
- W4313308905 hasConcept C2776870249 @default.
- W4313308905 hasConcept C2778943623 @default.
- W4313308905 hasConcept C2780115692 @default.
- W4313308905 hasConcept C2780801004 @default.
- W4313308905 hasConcept C523546767 @default.
- W4313308905 hasConcept C54355233 @default.
- W4313308905 hasConcept C55493867 @default.
- W4313308905 hasConcept C86803240 @default.
- W4313308905 hasConcept C89423630 @default.
- W4313308905 hasConcept C91523082 @default.
- W4313308905 hasConceptScore W4313308905C104317684 @default.
- W4313308905 hasConceptScore W4313308905C143065580 @default.
- W4313308905 hasConceptScore W4313308905C147483822 @default.
- W4313308905 hasConceptScore W4313308905C159047783 @default.
- W4313308905 hasConceptScore W4313308905C203014093 @default.
- W4313308905 hasConceptScore W4313308905C2776870249 @default.
- W4313308905 hasConceptScore W4313308905C2778943623 @default.
- W4313308905 hasConceptScore W4313308905C2780115692 @default.
- W4313308905 hasConceptScore W4313308905C2780801004 @default.
- W4313308905 hasConceptScore W4313308905C523546767 @default.
- W4313308905 hasConceptScore W4313308905C54355233 @default.
- W4313308905 hasConceptScore W4313308905C55493867 @default.
- W4313308905 hasConceptScore W4313308905C86803240 @default.
- W4313308905 hasConceptScore W4313308905C89423630 @default.
- W4313308905 hasConceptScore W4313308905C91523082 @default.
- W4313308905 hasIssue "3" @default.
- W4313308905 hasLocation W43133089051 @default.
- W4313308905 hasOpenAccess W4313308905 @default.
- W4313308905 hasPrimaryLocation W43133089051 @default.
- W4313308905 hasRelatedWork W1899176882 @default.
- W4313308905 hasRelatedWork W1921524104 @default.
- W4313308905 hasRelatedWork W2044954461 @default.
- W4313308905 hasRelatedWork W2078952439 @default.
- W4313308905 hasRelatedWork W2097919150 @default.
- W4313308905 hasRelatedWork W2104180324 @default.
- W4313308905 hasRelatedWork W2409271623 @default.
- W4313308905 hasRelatedWork W2419404186 @default.
- W4313308905 hasRelatedWork W2427331160 @default.
- W4313308905 hasRelatedWork W4313308905 @default.
- W4313308905 hasVolume "108" @default.
- W4313308905 isParatext "false" @default.
- W4313308905 isRetracted "false" @default.
- W4313308905 workType "article" @default.