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- W4313308964 abstract "Abstract Adult rats received 750 or 800 R of whole body x-irradiation with simultaneous thymic or splenic shielding and immediately thereafter were given intrathymic, intrasplenic, or intraperitoneal injections of suspensions of rat spinal cord or acid-extracted rat cord encephalitogen. Three weeks later the animals were challenged with the corresponding antigen in Freund's adjuvant. Animals receiving intrathymic encephalitogenic material showed a slight but definite decrease in the severity of experimental autoallergic encephalomyelitis (EAE). The acid-extracted encephalitogen showed four components after filtration through Sephadex G-200. Electrophoresis on 5% acrylamide gel in the presence of 8 M urea revealed at least four cathodally migrating and four anodally migrating bands." @default.
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- W4313308964 date "1970-07-01" @default.
- W4313308964 modified "2023-10-16" @default.
- W4313308964 title "Role of the Thymus in Tolerance" @default.
- W4313308964 doi "https://doi.org/10.4049/jimmunol.105.1.322" @default.
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