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- W4313309037 abstract "Abstract Thymectomized mice produced a significantly lower level of antibody against human serum albumin (HSA) and the decrease in total antibody activity was due to a decrease in the IgG1 while the other immunoglobulin classes were largely unaffected. The same animals did produce a normal response in all immunoglobulin classes to a high dose of keyhole limpet hemocyanin (KLH). However, a low dose (1 µg) of the same antigen produced a poor response in thymectomized mice, and, as was found with HSA, IgG1 was the main immunoglobulin class affected. It is concluded a) that KLH is a “non-thymic-dependent” antigen only at a relatively high dose and b) that of all the immunoglobulin classes only IgG1 is thymic-dependent." @default.
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- W4313309037 date "1972-01-01" @default.
- W4313309037 modified "2023-10-09" @default.
- W4313309037 title "Quantitative Estimation of Antibody in the Immunoglobulin Classes of the Mouse" @default.
- W4313309037 doi "https://doi.org/10.4049/jimmunol.108.1.161" @default.
- W4313309037 hasPublicationYear "1972" @default.
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