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- W4313309054 abstract "Abstract Recent studies on the mode of action of antilymphocytic serum (ALS) have suggested that its primary site of action is on the thymus-derived small lymphocyte (1, 2). It has also been suggested that these cells are eliminated rather than temporarily inactivated (3) and that an important part of this process is opsonization followed by phagocytosis (2). Greaves et al. (4) recently showed that there was a significant correlation between the immunosuppressive potency of ALS, and its opsonic titer as estimated by a technique involving the adherence of opsonized mouse lymphocytes to mouse peritoneal macrophages in monolayer culture. The present communication describes macrophage-cytophilic antibody in rabbit anti-mouse-lymphocytic serum (RAMLS). This may well be of significance in relation to the work cited above, as cytophilia has been defined as the property of opsonizing antibody which provides the receptors that permit binding of antigen to the macrophage cell membrane in preparation for phagocytosis (5)." @default.
- W4313309054 created "2023-01-06" @default.
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- W4313309054 date "1969-05-01" @default.
- W4313309054 modified "2023-09-28" @default.
- W4313309054 title "Cytophilic Antibody in Heterologous Antilymphocytic Serum: Its Presence, Absorption and Possible Biologic Significance" @default.
- W4313309054 doi "https://doi.org/10.4049/jimmunol.102.5.1329" @default.
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