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- W4313309433 abstract "Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral agent responsible for COVID-19 and belongs to the Coronavirus family. Viral particles are shaped spherically and contain projections on the surface named S proteins, which are responsible for inducing the host immune response and infectivity. Protein S is a homotrimeric type 1 transmembrane protein and is subdivided into two subunits, S1 and S2. The S1 subunit interacts with angiotensin-converting enzyme 2, while the S2 subunit mediates the fusion process. Coronavirus possesses large genetic material composed of an unsegmented positive single-stranded RNA. It contains multiple open reading frames producing 15 or 16 nonstructural proteins; structural proteins S, E, M, and N; and accessory proteins. The primary route of transmission is exposure to infectious respiratory fluid. The World Health Organization has categorized four SARS-CoV-2 variants as variants of concern: alpha, beta, delta, and gamma." @default.
- W4313309433 created "2023-01-06" @default.
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- W4313309433 date "2022-12-30" @default.
- W4313309433 modified "2023-10-16" @default.
- W4313309433 title "COVID‐19: Virology" @default.
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- W4313309433 doi "https://doi.org/10.1002/9781119789741.ch2" @default.
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