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- W4313309516 abstract "This chapter describes the epidemiology, aetiology, pathogenesis, virulence factors, clinical manifestations and treatment of oral candidosis. Candida albicans accounts for approximately 95% of oral candidosis infections. In order to cause infection, Candida must be retained in the mouth and adhere to mucosal surfaces. Therefore, the washing effects of salivation and swallowing are important factors in host defence against Candida growth. Patients undergoing radiotherapy for head and neck cancer are susceptible to candidosis during and post-treatment. For over 30 years, imidazoles and triazoles have been used in the treatment of oral candidal infections. Possible side effects of systemically administered antifungals should be considered, and this may preclude their use in some patients. The echinocandin caspofungin administered intravenously is effective in managing patients with invasive candidosis or candidaemia with a fewer side effects then parenterally administered amphotericin B." @default.
- W4313309516 created "2023-01-06" @default.
- W4313309516 creator A5086209312 @default.
- W4313309516 date "2022-12-30" @default.
- W4313309516 modified "2023-10-12" @default.
- W4313309516 title "Oral Manifestations of Candidosis" @default.
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- W4313309516 doi "https://doi.org/10.1002/9781119826781.ch18" @default.
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