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- W4313309908 startingPage "1119" @default.
- W4313309908 abstract "Abstract By using a radioactive immune coprecipitation technique, supernatants of lymph node cells from immunized rabbits incubated with keyhole limpet hemocyanin (KLH) were shown to enhance γ-globulin synthesis and anti-KLH antibody production of KLH-primed and nonprimed lymphoid cells from the peripheral blood and lymph nodes in the presence of KLH in vitro. Similarly, when KLH-stimulated supernatants were added both to BSA-primed and nonprimed lymphocyte cultures in the presence of BSA, increases in γ-globulin and anti-BSA synthesis were observed. The data presented provide evidence that a soluble factor is released by antigen-stimulated lymphocytes which enhances immunoglobulin and specific antibody production in a nonspecific manner. The evidence obtained suggests that the factor may be a lymphokine which either directly or indirectly stimulates bone marrow-derived lymphocyte function in both the primary and secondary responses." @default.
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- W4313309908 date "1973-10-01" @default.
- W4313309908 modified "2023-10-06" @default.
- W4313309908 title "Stimulation of γ-Globulin Synthesis and Specific Antibody Production by a Factor Released by Activated Lymphocytes" @default.
- W4313309908 doi "https://doi.org/10.4049/jimmunol.111.4.1119" @default.
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