Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313316357> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W4313316357 endingPage "271" @default.
- W4313316357 startingPage "269" @default.
- W4313316357 abstract "Abstract Several years ago the 7 S guinea pig immunoglobulins were separated into two well-defined electrophoretic classes: the slowly migrating γ2 and the more rapid γ1 (1–3). This achievement led to further studies which demonstrated that the ability to activate the complement (C′) sequence was confined to γ2 immunoglobulins. These antibodies failed to mediate passive cutaneous anaphylaxis (PCA) in the guinea pig. In contrast, the γ1 immunoglobulins were capable of eliciting PCA reactions despite their purported deficiency in C′-fixing potency. We have re-investigated this question and have confirmed all the previous findings excepting the C′-fixing properties of γ1 type antibodies. These immunoglobulins do interact with guinea pig C′ components, but probably by a different pathway. Hartley strain guinea pigs were immunized with highly substituted dinitrophenylated bovine γ globulin (4) emulsified in complete Freund's adjuvant as described in (5). Initially, 250 µg of antigen were injected into each of the four toepads." @default.
- W4313316357 created "2023-01-06" @default.
- W4313316357 creator A5048182028 @default.
- W4313316357 creator A5059064215 @default.
- W4313316357 creator A5065624443 @default.
- W4313316357 creator A5073296631 @default.
- W4313316357 date "1969-01-01" @default.
- W4313316357 modified "2023-10-18" @default.
- W4313316357 title "The Fixation of Guinea Pig Complement by γ1 and γ2 Immunoglobulins" @default.
- W4313316357 doi "https://doi.org/10.4049/jimmunol.102.1.269" @default.
- W4313316357 hasPublicationYear "1969" @default.
- W4313316357 type Work @default.
- W4313316357 citedByCount "14" @default.
- W4313316357 crossrefType "journal-article" @default.
- W4313316357 hasAuthorship W4313316357A5048182028 @default.
- W4313316357 hasAuthorship W4313316357A5059064215 @default.
- W4313316357 hasAuthorship W4313316357A5065624443 @default.
- W4313316357 hasAuthorship W4313316357A5073296631 @default.
- W4313316357 hasBestOaLocation W43133163571 @default.
- W4313316357 hasConcept C134018914 @default.
- W4313316357 hasConcept C147483822 @default.
- W4313316357 hasConcept C152669594 @default.
- W4313316357 hasConcept C153911025 @default.
- W4313316357 hasConcept C159654299 @default.
- W4313316357 hasConcept C185592680 @default.
- W4313316357 hasConcept C202751555 @default.
- W4313316357 hasConcept C203014093 @default.
- W4313316357 hasConcept C2777863537 @default.
- W4313316357 hasConcept C2778815084 @default.
- W4313316357 hasConcept C45189115 @default.
- W4313316357 hasConcept C55493867 @default.
- W4313316357 hasConcept C57992300 @default.
- W4313316357 hasConcept C79162176 @default.
- W4313316357 hasConcept C86803240 @default.
- W4313316357 hasConceptScore W4313316357C134018914 @default.
- W4313316357 hasConceptScore W4313316357C147483822 @default.
- W4313316357 hasConceptScore W4313316357C152669594 @default.
- W4313316357 hasConceptScore W4313316357C153911025 @default.
- W4313316357 hasConceptScore W4313316357C159654299 @default.
- W4313316357 hasConceptScore W4313316357C185592680 @default.
- W4313316357 hasConceptScore W4313316357C202751555 @default.
- W4313316357 hasConceptScore W4313316357C203014093 @default.
- W4313316357 hasConceptScore W4313316357C2777863537 @default.
- W4313316357 hasConceptScore W4313316357C2778815084 @default.
- W4313316357 hasConceptScore W4313316357C45189115 @default.
- W4313316357 hasConceptScore W4313316357C55493867 @default.
- W4313316357 hasConceptScore W4313316357C57992300 @default.
- W4313316357 hasConceptScore W4313316357C79162176 @default.
- W4313316357 hasConceptScore W4313316357C86803240 @default.
- W4313316357 hasIssue "1" @default.
- W4313316357 hasLocation W43133163571 @default.
- W4313316357 hasOpenAccess W4313316357 @default.
- W4313316357 hasPrimaryLocation W43133163571 @default.
- W4313316357 hasRelatedWork W1539989077 @default.
- W4313316357 hasRelatedWork W1674135449 @default.
- W4313316357 hasRelatedWork W1742143217 @default.
- W4313316357 hasRelatedWork W1945848208 @default.
- W4313316357 hasRelatedWork W2061622709 @default.
- W4313316357 hasRelatedWork W2312513188 @default.
- W4313316357 hasRelatedWork W234429444 @default.
- W4313316357 hasRelatedWork W2395223956 @default.
- W4313316357 hasRelatedWork W2397693230 @default.
- W4313316357 hasRelatedWork W4313316357 @default.
- W4313316357 hasVolume "102" @default.
- W4313316357 isParatext "false" @default.
- W4313316357 isRetracted "false" @default.
- W4313316357 workType "article" @default.