FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313331229> ?p ?o ?g. }

• W4313331229 abstract "Abstract Background Noninvasive ventilation (NIV) is the recommended mode of ventilation used in acute respiratory failure secondary to an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Recent data has shown that high-flow nasal cannula (HFNC) treatment can be an alternative for patients with hypercapnic respiratory failure. The purpose of this study is to evaluate HFNC with sequential NIV versus NIV alone as the initial ventilatory strategy in AECOPD. Methods This investigator-initiated, unblinded, single center, randomized controlled trial will be conducted in the emergency department, emergency intensive care unit, or respiratory intensive care unit of a tertiary-care urban teaching hospital. A total of 66 patients will be enrolled and randomized into the intervention group (HFNC with sequential NIV) or the control group (NIV group). The primary endpoint will be the mean difference in PaCO 2 from baseline to 24 h after randomization. Secondary endpoints include the mean difference in PaCO 2 from baseline to 6, 12, and 18 h, as well as the dyspnea score, overall discomfort score, rate of treatment failure, respiratory rate, rate of endotracheal intubation, length of hospital stay, and mortality. Discussion Taking the advantages of both HFNC and NIV on AECOPD patients into account, we designed this clinical trial to investigate the combination of these ventilatory strategies. This trial will help us understand how HFNC with sequential NIV compares to NIV alone in treating AECOPD patients. Trial registration ChiCTR2100054809." @default.
• W4313331229 created "2023-01-06" @default.
• W4313331229 creator A5007807826 @default.
• W4313331229 creator A5020683386 @default.
• W4313331229 creator A5038460341 @default.
• W4313331229 creator A5038805449 @default.
• W4313331229 creator A5055255943 @default.
• W4313331229 creator A5068634054 @default.
• W4313331229 date "2022-12-29" @default.
• W4313331229 modified "2023-10-18" @default.
• W4313331229 title "High-flow nasal cannula therapy with sequential noninvasive ventilation versus noninvasive ventilation alone as the initial ventilatory strategy in acute COPD exacerbations: study protocol for a randomized controlled trial" @default.
• W4313331229 cites W2068887333 @default.
• W4313331229 cites W2121949552 @default.
• W4313331229 cites W2170714046 @default.
• W4313331229 cites W2329899462 @default.
• W4313331229 cites W2405289598 @default.
• W4313331229 cites W2583265473 @default.
• W4313331229 cites W2611630178 @default.
• W4313331229 cites W2622627189 @default.
• W4313331229 cites W2794019240 @default.
• W4313331229 cites W2901561058 @default.
• W4313331229 cites W2908715463 @default.
• W4313331229 cites W2924109498 @default.
• W4313331229 cites W2946738300 @default.
• W4313331229 cites W2960720806 @default.
• W4313331229 cites W2978981142 @default.
• W4313331229 cites W3002917038 @default.
• W4313331229 cites W3003591188 @default.
• W4313331229 cites W3033914233 @default.
• W4313331229 cites W3045854737 @default.
• W4313331229 cites W3047301060 @default.
• W4313331229 cites W3048880772 @default.
• W4313331229 cites W3107100502 @default.
• W4313331229 cites W3107242054 @default.
• W4313331229 cites W3111623578 @default.
• W4313331229 cites W3116001454 @default.
• W4313331229 doi "https://doi.org/10.1186/s13063-022-06963-w" @default.
• W4313331229 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36581995" @default.
• W4313331229 hasPublicationYear "2022" @default.
• W4313331229 type Work @default.
• W4313331229 citedByCount "1" @default.
• W4313331229 countsByYear W43133312292023 @default.
• W4313331229 crossrefType "journal-article" @default.
• W4313331229 hasAuthorship W4313331229A5007807826 @default.
• W4313331229 hasAuthorship W4313331229A5020683386 @default.
• W4313331229 hasAuthorship W4313331229A5038460341 @default.
• W4313331229 hasAuthorship W4313331229A5038805449 @default.
• W4313331229 hasAuthorship W4313331229A5055255943 @default.
• W4313331229 hasAuthorship W4313331229A5068634054 @default.
• W4313331229 hasBestOaLocation W43133312291 @default.
• W4313331229 hasConcept C118552586 @default.
• W4313331229 hasConcept C126322002 @default.
• W4313331229 hasConcept C127413603 @default.
• W4313331229 hasConcept C141071460 @default.
• W4313331229 hasConcept C168563851 @default.
• W4313331229 hasConcept C177713679 @default.
• W4313331229 hasConcept C200457457 @default.
• W4313331229 hasConcept C203092338 @default.
• W4313331229 hasConcept C204243189 @default.
• W4313331229 hasConcept C2776376669 @default.
• W4313331229 hasConcept C2776780178 @default.
• W4313331229 hasConcept C2776888751 @default.
• W4313331229 hasConcept C2777014857 @default.
• W4313331229 hasConcept C2777953023 @default.
• W4313331229 hasConcept C2778074680 @default.
• W4313331229 hasConcept C2778716859 @default.
• W4313331229 hasConcept C2780334268 @default.
• W4313331229 hasConcept C2780724011 @default.
• W4313331229 hasConcept C2987404301 @default.
• W4313331229 hasConcept C42219234 @default.
• W4313331229 hasConcept C71924100 @default.
• W4313331229 hasConcept C78519656 @default.
• W4313331229 hasConcept C8213797 @default.
• W4313331229 hasConcept C84393581 @default.
• W4313331229 hasConceptScore W4313331229C118552586 @default.
• W4313331229 hasConceptScore W4313331229C126322002 @default.
• W4313331229 hasConceptScore W4313331229C127413603 @default.
• W4313331229 hasConceptScore W4313331229C141071460 @default.
• W4313331229 hasConceptScore W4313331229C168563851 @default.
• W4313331229 hasConceptScore W4313331229C177713679 @default.
• W4313331229 hasConceptScore W4313331229C200457457 @default.
• W4313331229 hasConceptScore W4313331229C203092338 @default.
• W4313331229 hasConceptScore W4313331229C204243189 @default.
• W4313331229 hasConceptScore W4313331229C2776376669 @default.
• W4313331229 hasConceptScore W4313331229C2776780178 @default.
• W4313331229 hasConceptScore W4313331229C2776888751 @default.
• W4313331229 hasConceptScore W4313331229C2777014857 @default.
• W4313331229 hasConceptScore W4313331229C2777953023 @default.
• W4313331229 hasConceptScore W4313331229C2778074680 @default.
• W4313331229 hasConceptScore W4313331229C2778716859 @default.
• W4313331229 hasConceptScore W4313331229C2780334268 @default.
• W4313331229 hasConceptScore W4313331229C2780724011 @default.
• W4313331229 hasConceptScore W4313331229C2987404301 @default.
• W4313331229 hasConceptScore W4313331229C42219234 @default.
• W4313331229 hasConceptScore W4313331229C71924100 @default.
• W4313331229 hasConceptScore W4313331229C78519656 @default.
• W4313331229 hasConceptScore W4313331229C8213797 @default.
• W4313331229 hasConceptScore W4313331229C84393581 @default.
• W4313331229 hasIssue "1" @default.
• W4313331229 hasLocation W43133312291 @default.

• next