Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313331367> ?p ?o ?g. }
- W4313331367 abstract "Abstract Background The long-term epidemiological surveillance of carbapenem-resistant Klebsiella pneumoniae (CRKP) bloodstream infection (BSI) is limited in China, and the impact of carbapenem resistance on mortality remains unknown. This study aimed to investigate the prevalence, factors and outcomes of CRKP BSI, and examine the attributable mortality of carbapenem resistance. Methods This retrospective study enrolled 87 patients with CRKP BSI and 321 patients with carbapenem-susceptible Klebsiella pneumoniae (CSKP) BSI from 2015 to 2020. Multivariate logistic regression was performed to identify risk factors for infection and mortality. Stabilized inverse probability of treatment weighting was applied to balance covariates. Cox regression and Kaplan-Meier curves were used to estimate the attributable mortality of carbapenem resistance. Results An alarming increasing trend of CRKP BSI was observed during the six years. Longer hospitalization stay, intensive care unit stay, blood purification and antibiotic exposure were risk factors for CRKP BSI, whereas primary BSI and underlying diabetes were factors for CSKP BSI. The crude 30-day mortality of CRKP BSI was independently associated with age ≥ 55 years, underlying hematological malignancies and blood purification, while the infection source from skin and soft tissue, urinary catheter and underlying chronic obstructive pulmonary disease were predictors for CSKP BSI. The hazard ratios reflecting the impact of carbapenem resistance on 30-day mortality was 1.586 (0.791–3.182). Conclusions The 30-day mortality was not attributed to carbapenem resistance in KP BSI. Infection control policies for severely ill patients with prolonged hospitalizations and intensive care and patients with blood purification should be strengthened for CRKP BSI management." @default.
- W4313331367 created "2023-01-06" @default.
- W4313331367 creator A5024357425 @default.
- W4313331367 creator A5033684035 @default.
- W4313331367 creator A5038478517 @default.
- W4313331367 creator A5047748578 @default.
- W4313331367 creator A5050487837 @default.
- W4313331367 creator A5055765857 @default.
- W4313331367 date "2022-12-29" @default.
- W4313331367 modified "2023-10-17" @default.
- W4313331367 title "Prevalence, risk factors and outcomes of carbapenem-resistant Klebsiella pneumoniae bloodstream infection" @default.
- W4313331367 cites W1990436230 @default.
- W4313331367 cites W2000445173 @default.
- W4313331367 cites W2051855929 @default.
- W4313331367 cites W2078779322 @default.
- W4313331367 cites W2142343447 @default.
- W4313331367 cites W2538058458 @default.
- W4313331367 cites W2555505520 @default.
- W4313331367 cites W2601382852 @default.
- W4313331367 cites W2615583214 @default.
- W4313331367 cites W2781555728 @default.
- W4313331367 cites W2929574154 @default.
- W4313331367 cites W2943594574 @default.
- W4313331367 cites W2945505394 @default.
- W4313331367 cites W2951121463 @default.
- W4313331367 cites W2973981981 @default.
- W4313331367 cites W2984306187 @default.
- W4313331367 cites W3001451171 @default.
- W4313331367 cites W3012215031 @default.
- W4313331367 cites W3031863087 @default.
- W4313331367 cites W3042667355 @default.
- W4313331367 cites W3114918623 @default.
- W4313331367 cites W3131298329 @default.
- W4313331367 cites W3135791115 @default.
- W4313331367 cites W3138313195 @default.
- W4313331367 cites W3147639018 @default.
- W4313331367 cites W3175692108 @default.
- W4313331367 cites W3213159307 @default.
- W4313331367 cites W4221014084 @default.
- W4313331367 cites W4221061642 @default.
- W4313331367 cites W4225854351 @default.
- W4313331367 cites W4225939378 @default.
- W4313331367 cites W4283717169 @default.
- W4313331367 doi "https://doi.org/10.21203/rs.3.rs-2403286/v1" @default.
- W4313331367 hasPublicationYear "2022" @default.
- W4313331367 type Work @default.
- W4313331367 citedByCount "0" @default.
- W4313331367 crossrefType "posted-content" @default.
- W4313331367 hasAuthorship W4313331367A5024357425 @default.
- W4313331367 hasAuthorship W4313331367A5033684035 @default.
- W4313331367 hasAuthorship W4313331367A5038478517 @default.
- W4313331367 hasAuthorship W4313331367A5047748578 @default.
- W4313331367 hasAuthorship W4313331367A5050487837 @default.
- W4313331367 hasAuthorship W4313331367A5055765857 @default.
- W4313331367 hasBestOaLocation W43133313671 @default.
- W4313331367 hasConcept C104317684 @default.
- W4313331367 hasConcept C126322002 @default.
- W4313331367 hasConcept C151956035 @default.
- W4313331367 hasConcept C177713679 @default.
- W4313331367 hasConcept C179755657 @default.
- W4313331367 hasConcept C185592680 @default.
- W4313331367 hasConcept C2776376669 @default.
- W4313331367 hasConcept C2776685102 @default.
- W4313331367 hasConcept C2777058267 @default.
- W4313331367 hasConcept C2779443120 @default.
- W4313331367 hasConcept C501593827 @default.
- W4313331367 hasConcept C50382708 @default.
- W4313331367 hasConcept C547475151 @default.
- W4313331367 hasConcept C55493867 @default.
- W4313331367 hasConcept C71924100 @default.
- W4313331367 hasConcept C86803240 @default.
- W4313331367 hasConcept C89423630 @default.
- W4313331367 hasConceptScore W4313331367C104317684 @default.
- W4313331367 hasConceptScore W4313331367C126322002 @default.
- W4313331367 hasConceptScore W4313331367C151956035 @default.
- W4313331367 hasConceptScore W4313331367C177713679 @default.
- W4313331367 hasConceptScore W4313331367C179755657 @default.
- W4313331367 hasConceptScore W4313331367C185592680 @default.
- W4313331367 hasConceptScore W4313331367C2776376669 @default.
- W4313331367 hasConceptScore W4313331367C2776685102 @default.
- W4313331367 hasConceptScore W4313331367C2777058267 @default.
- W4313331367 hasConceptScore W4313331367C2779443120 @default.
- W4313331367 hasConceptScore W4313331367C501593827 @default.
- W4313331367 hasConceptScore W4313331367C50382708 @default.
- W4313331367 hasConceptScore W4313331367C547475151 @default.
- W4313331367 hasConceptScore W4313331367C55493867 @default.
- W4313331367 hasConceptScore W4313331367C71924100 @default.
- W4313331367 hasConceptScore W4313331367C86803240 @default.
- W4313331367 hasConceptScore W4313331367C89423630 @default.
- W4313331367 hasLocation W43133313671 @default.
- W4313331367 hasOpenAccess W4313331367 @default.
- W4313331367 hasPrimaryLocation W43133313671 @default.
- W4313331367 hasRelatedWork W1718193276 @default.
- W4313331367 hasRelatedWork W1877476828 @default.
- W4313331367 hasRelatedWork W1999081204 @default.
- W4313331367 hasRelatedWork W2014138767 @default.
- W4313331367 hasRelatedWork W2059595009 @default.
- W4313331367 hasRelatedWork W2089720823 @default.
- W4313331367 hasRelatedWork W2163832044 @default.
- W4313331367 hasRelatedWork W2291901766 @default.