Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313331472> ?p ?o ?g. }
Showing items 1 to 55 of
55
with 100 items per page.
- W4313331472 abstract "the coagulation factors VIII (FVIII) or IX (FIX), respectively. The primary therapeutic approach is to replace the deficient coagulation factor, which can be achieved with factors derived from human plasma or recombinants. However, despite having a therapeutic approach, most severe cases are symptomatic and may have complications, mainly in the muscles and joints. One example of such disorder is hemarthrosis. This manifestation tends to affect mainly the knee, ankle, or elbow joints in about 80% of cases. Objective: to describe the primary forms of treatment for joint bleeding in patients with severe hemophilia. Methods: This is a qualitative research of the integrative review type meant to identify productions on topics associated with hemarthrosis and severe hemophilia. The articles were searched through the databases PubMed, Scientific Electronic Library Online (Scielo) and Virtual Health Library (BVS) with the following search descriptors: “hemarthrosis andhemophilia”; “joint diseases and Hemophilia” and corresponding terms in Portuguese. The inclusion criteria were as follows:a) scientific articles b) available in full-text c) studies available in Portuguese, English, or Spanish d) randomized clinical trials e) articles published between 2016 and 2021 f) articles containing hemarthrosis caused by severe hemophilia. As exclusion criteria, texts that had no relation to the theme, did not answer the guiding question, other types of articles that did not include randomized clinical trials and/or presented duplicates were discarded. Results: In total, 42 articles were found in the selected databases; eight were duplicated, and 25 were excluded for not being randomized clinical trials or because they did not contemplate the theme. After careful reading, nine articles that met the inclusion and exclusion criteria were identified. Of the eligible studies, one reported factor replacement, and eight reported physiotherapeutic treatment. Conclusion: Factor replacement for hemophilic patients is essential and, based on the information obtained, early replacement is beneficial for the patient to avoid joint complications. Prophylaxis is indicated in severe hemophilia and its main objective is to prevent recurrent hemarthrosis, which can cause permanent functional deformities. Some physiotherapeutic interventions are indicated to prevent joint damage in severe hemophilic patients. The findings show diversity in the physical therapy modalities employed. The complete prevention of joint damage is still a challenge. A combination of treatments and a multidisciplinary team follow-up is necessary to ensure health and quality of life of patients." @default.
- W4313331472 created "2023-01-06" @default.
- W4313331472 creator A5019732247 @default.
- W4313331472 creator A5044467002 @default.
- W4313331472 creator A5052800738 @default.
- W4313331472 creator A5073223540 @default.
- W4313331472 creator A5080658296 @default.
- W4313331472 creator A5081550640 @default.
- W4313331472 date "2022-12-27" @default.
- W4313331472 modified "2023-09-25" @default.
- W4313331472 title "Therapeutic options for hemarthrosis in severe hemophilic patients" @default.
- W4313331472 doi "https://doi.org/10.11606/issn.2176-7262.rmrp.2022.196511" @default.
- W4313331472 hasPublicationYear "2022" @default.
- W4313331472 type Work @default.
- W4313331472 citedByCount "0" @default.
- W4313331472 crossrefType "journal-article" @default.
- W4313331472 hasAuthorship W4313331472A5019732247 @default.
- W4313331472 hasAuthorship W4313331472A5044467002 @default.
- W4313331472 hasAuthorship W4313331472A5052800738 @default.
- W4313331472 hasAuthorship W4313331472A5073223540 @default.
- W4313331472 hasAuthorship W4313331472A5080658296 @default.
- W4313331472 hasAuthorship W4313331472A5081550640 @default.
- W4313331472 hasBestOaLocation W43133314721 @default.
- W4313331472 hasConcept C141071460 @default.
- W4313331472 hasConcept C168563851 @default.
- W4313331472 hasConcept C187212893 @default.
- W4313331472 hasConcept C2776478404 @default.
- W4313331472 hasConcept C2779526002 @default.
- W4313331472 hasConcept C2779936836 @default.
- W4313331472 hasConcept C71924100 @default.
- W4313331472 hasConceptScore W4313331472C141071460 @default.
- W4313331472 hasConceptScore W4313331472C168563851 @default.
- W4313331472 hasConceptScore W4313331472C187212893 @default.
- W4313331472 hasConceptScore W4313331472C2776478404 @default.
- W4313331472 hasConceptScore W4313331472C2779526002 @default.
- W4313331472 hasConceptScore W4313331472C2779936836 @default.
- W4313331472 hasConceptScore W4313331472C71924100 @default.
- W4313331472 hasIssue "4" @default.
- W4313331472 hasLocation W43133314721 @default.
- W4313331472 hasOpenAccess W4313331472 @default.
- W4313331472 hasPrimaryLocation W43133314721 @default.
- W4313331472 hasRelatedWork W2003938723 @default.
- W4313331472 hasRelatedWork W2017532146 @default.
- W4313331472 hasRelatedWork W2047967234 @default.
- W4313331472 hasRelatedWork W2118496982 @default.
- W4313331472 hasRelatedWork W2364998975 @default.
- W4313331472 hasRelatedWork W2369162477 @default.
- W4313331472 hasRelatedWork W2439875401 @default.
- W4313331472 hasRelatedWork W3116990902 @default.
- W4313331472 hasRelatedWork W4238867864 @default.
- W4313331472 hasRelatedWork W2525756941 @default.
- W4313331472 hasVolume "55" @default.
- W4313331472 isParatext "false" @default.
- W4313331472 isRetracted "false" @default.
- W4313331472 workType "article" @default.