FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313331532> ?p ?o ?g. }

• W4313331532 endingPage "13" @default.
• W4313331532 startingPage "1" @default.
• W4313331532 abstract "The immunomodulatory role of monocytes is essential for tissue healing and can influence the osseointegration of implanted materials. Properties such as the surface structure, hydrophilicity, and roughness of the implanted materials can modulate monocyte–macrophage function. In this study, we characterized material-hydrogenated TiO2 nanotubes (H-TNT) with superhydrophilic surfaces to investigate the effect of H-TNT on macrophage polarization and osseointegration. H-TNT were prepared by anodic oxidation and hydrogenation and used in the experimental group, while TNT and smooth pure Ti were employed in the control groups. RAW264.7 cells were selected to observe the immunomodulatory effect of these samples. The cell morphology was observed via scanning electron microscopy, and cytokine expression was detected using an enzyme-linked immunosorbent assay and immunofluorescence staining. After 24 hr of cultivation, the macrophage-conditioned medium was collected and used for indirect coculture with MC3T3-E1 cells. The morphology of MC3T3-E1 cells was observed using fluorescence staining. Cell adhesion and proliferation were measured using the Cell Counting Kit-8 assay. Alkaline phosphatase activity measurement, alizarin red staining, calcium quantification, and reverse transcription polymerase chain reaction were performed to assess the osteogenic differentiation of MC3T3-E1 cells. The results showed that H-TNT promoted the M2-type polarization of macrophages, which in turn influenced the adhesion, proliferation, and osteogenic differentiation of MC3T3-E1 cells. These materials can serve as useful candidates for bone implants because they activate macrophages to produce a favorable osteoimmunomodulatory microenvironment." @default.
• W4313331532 created "2023-01-06" @default.
• W4313331532 creator A5006822602 @default.
• W4313331532 creator A5024016470 @default.
• W4313331532 creator A5039783554 @default.
• W4313331532 creator A5045965538 @default.
• W4313331532 creator A5049767419 @default.
• W4313331532 creator A5060657337 @default.
• W4313331532 creator A5089175200 @default.
• W4313331532 date "2022-12-29" @default.
• W4313331532 modified "2023-10-17" @default.
• W4313331532 title "Hydrogenated TiO2 Nanotubes Regulate Osseointegration by Influencing Macrophage Polarization in the Osteogenic Environment" @default.
• W4313331532 cites W1996852610 @default.
• W4313331532 cites W2008419577 @default.
• W4313331532 cites W2016091065 @default.
• W4313331532 cites W2018210705 @default.
• W4313331532 cites W2024616045 @default.
• W4313331532 cites W2054472394 @default.
• W4313331532 cites W2057940657 @default.
• W4313331532 cites W2063063715 @default.
• W4313331532 cites W2072958401 @default.
• W4313331532 cites W2084193236 @default.
• W4313331532 cites W2093705034 @default.
• W4313331532 cites W2111471786 @default.
• W4313331532 cites W2123394214 @default.
• W4313331532 cites W2145749163 @default.
• W4313331532 cites W2159442019 @default.
• W4313331532 cites W2161598381 @default.
• W4313331532 cites W2166089243 @default.
• W4313331532 cites W2193505608 @default.
• W4313331532 cites W2194806179 @default.
• W4313331532 cites W2203624770 @default.
• W4313331532 cites W2219595372 @default.
• W4313331532 cites W2257608894 @default.
• W4313331532 cites W2283090762 @default.
• W4313331532 cites W2338968478 @default.
• W4313331532 cites W2404121463 @default.
• W4313331532 cites W2581606583 @default.
• W4313331532 cites W2590043924 @default.
• W4313331532 cites W2598088811 @default.
• W4313331532 cites W2752468329 @default.
• W4313331532 cites W2769662050 @default.
• W4313331532 cites W2779902212 @default.
• W4313331532 cites W2790073117 @default.
• W4313331532 cites W2791330284 @default.
• W4313331532 cites W2795035343 @default.
• W4313331532 cites W2796157093 @default.
• W4313331532 cites W2804357096 @default.
• W4313331532 cites W2805910384 @default.
• W4313331532 cites W2808067098 @default.
• W4313331532 cites W2841068772 @default.
• W4313331532 cites W2867737929 @default.
• W4313331532 cites W2885305610 @default.
• W4313331532 cites W2889510095 @default.
• W4313331532 cites W2892464396 @default.
• W4313331532 cites W2902072746 @default.
• W4313331532 cites W2910745688 @default.
• W4313331532 cites W2925666171 @default.
• W4313331532 cites W2936026527 @default.
• W4313331532 cites W2945786100 @default.
• W4313331532 cites W3003916947 @default.
• W4313331532 cites W3037804305 @default.
• W4313331532 cites W3146582890 @default.
• W4313331532 cites W3146876044 @default.
• W4313331532 cites W3147490358 @default.
• W4313331532 cites W3155959282 @default.
• W4313331532 cites W3204717560 @default.
• W4313331532 doi "https://doi.org/10.1155/2022/2650421" @default.
• W4313331532 hasPublicationYear "2022" @default.
• W4313331532 type Work @default.
• W4313331532 citedByCount "0" @default.
• W4313331532 crossrefType "journal-article" @default.
• W4313331532 hasAuthorship W4313331532A5006822602 @default.
• W4313331532 hasAuthorship W4313331532A5024016470 @default.
• W4313331532 hasAuthorship W4313331532A5039783554 @default.
• W4313331532 hasAuthorship W4313331532A5045965538 @default.
• W4313331532 hasAuthorship W4313331532A5049767419 @default.
• W4313331532 hasAuthorship W4313331532A5060657337 @default.
• W4313331532 hasAuthorship W4313331532A5089175200 @default.
• W4313331532 hasBestOaLocation W43133315321 @default.
• W4313331532 hasConcept C101414908 @default.
• W4313331532 hasConcept C12554922 @default.
• W4313331532 hasConcept C141071460 @default.
• W4313331532 hasConcept C142724271 @default.
• W4313331532 hasConcept C1491633281 @default.
• W4313331532 hasConcept C159985019 @default.
• W4313331532 hasConcept C160160445 @default.
• W4313331532 hasConcept C181199279 @default.
• W4313331532 hasConcept C185592680 @default.
• W4313331532 hasConcept C192562407 @default.
• W4313331532 hasConcept C202751555 @default.
• W4313331532 hasConcept C203014093 @default.
• W4313331532 hasConcept C2776682551 @default.
• W4313331532 hasConcept C2779244956 @default.
• W4313331532 hasConcept C2781184567 @default.
• W4313331532 hasConcept C2781411149 @default.
• W4313331532 hasConcept C55493867 @default.
• W4313331532 hasConcept C71924100 @default.

• next