Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313332694> ?p ?o ?g. }
- W4313332694 abstract "Abstract The human gut microbiome has been extensively explored, while the archaeal viruses remain largely unknown. Here, we present a comprehensive analysis of the archaeal viruses from the human gut metagenomes and the existing virus collections using the CRISPR spacer and viral signature-based approach. This results in 1279 viral species, of which, 95.2% infect Methanobrevibacteria_A , 56.5% shared high identity (>95%) with the archaeal proviruses, 37.2% have a host range across archaeal species, and 55.7% are highly prevalent in the human population (>1%). A methanogenic archaeal virus-specific gene for pseudomurein endoisopeptidase (PeiW) frequently occurs in the viral sequences ( n = 150). Analysis of 33 Caudoviricetes viruses with a complete genome often discovers the genes ( integrase , n = 29; mazE , n = 10) regulating the viral lysogenic-lytic cycle, implying the dominance of temperate viruses in the archaeal virome. Together, our work uncovers the unexplored diversity of archaeal viruses, revealing the novel facet of the human gut microbiome." @default.
- W4313332694 created "2023-01-06" @default.
- W4313332694 creator A5011929536 @default.
- W4313332694 creator A5012136645 @default.
- W4313332694 creator A5038336906 @default.
- W4313332694 creator A5068176076 @default.
- W4313332694 creator A5086637212 @default.
- W4313332694 date "2022-12-29" @default.
- W4313332694 modified "2023-10-05" @default.
- W4313332694 title "Metagenomic analysis reveals unexplored diversity of archaeal virome in the human gut" @default.
- W4313332694 cites W1519266993 @default.
- W4313332694 cites W1964218165 @default.
- W4313332694 cites W2045204781 @default.
- W4313332694 cites W2075420514 @default.
- W4313332694 cites W2084814249 @default.
- W4313332694 cites W2097341408 @default.
- W4313332694 cites W2111647009 @default.
- W4313332694 cites W2112364185 @default.
- W4313332694 cites W2119859604 @default.
- W4313332694 cites W2120902911 @default.
- W4313332694 cites W2127391962 @default.
- W4313332694 cites W2131157113 @default.
- W4313332694 cites W2131186249 @default.
- W4313332694 cites W2135614314 @default.
- W4313332694 cites W2138122982 @default.
- W4313332694 cites W2141052558 @default.
- W4313332694 cites W2143485490 @default.
- W4313332694 cites W2146341019 @default.
- W4313332694 cites W2170747616 @default.
- W4313332694 cites W2171334674 @default.
- W4313332694 cites W2223752691 @default.
- W4313332694 cites W2245444176 @default.
- W4313332694 cites W2514983714 @default.
- W4313332694 cites W2527154582 @default.
- W4313332694 cites W2545536333 @default.
- W4313332694 cites W2626026865 @default.
- W4313332694 cites W2732139758 @default.
- W4313332694 cites W2753961085 @default.
- W4313332694 cites W2767476008 @default.
- W4313332694 cites W2768095751 @default.
- W4313332694 cites W2770677113 @default.
- W4313332694 cites W2792293704 @default.
- W4313332694 cites W2799524357 @default.
- W4313332694 cites W2804606747 @default.
- W4313332694 cites W2898402099 @default.
- W4313332694 cites W2903760905 @default.
- W4313332694 cites W2904384071 @default.
- W4313332694 cites W2909790134 @default.
- W4313332694 cites W2943223175 @default.
- W4313332694 cites W2949841808 @default.
- W4313332694 cites W2979358136 @default.
- W4313332694 cites W2986925300 @default.
- W4313332694 cites W2989706094 @default.
- W4313332694 cites W2997984836 @default.
- W4313332694 cites W3003110834 @default.
- W4313332694 cites W3015625496 @default.
- W4313332694 cites W3019706413 @default.
- W4313332694 cites W3033929089 @default.
- W4313332694 cites W3035822879 @default.
- W4313332694 cites W3042305844 @default.
- W4313332694 cites W3042609513 @default.
- W4313332694 cites W3048366898 @default.
- W4313332694 cites W3081166727 @default.
- W4313332694 cites W3097008984 @default.
- W4313332694 cites W3118048495 @default.
- W4313332694 cites W3127656915 @default.
- W4313332694 cites W3132890345 @default.
- W4313332694 cites W3133726023 @default.
- W4313332694 cites W3134954922 @default.
- W4313332694 cites W3156458251 @default.
- W4313332694 cites W3161179294 @default.
- W4313332694 cites W3173385890 @default.
- W4313332694 cites W3176037658 @default.
- W4313332694 cites W3186499237 @default.
- W4313332694 cites W3189053267 @default.
- W4313332694 cites W4200296342 @default.
- W4313332694 cites W4283706528 @default.
- W4313332694 doi "https://doi.org/10.1038/s41467-022-35735-y" @default.
- W4313332694 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36581612" @default.
- W4313332694 hasPublicationYear "2022" @default.
- W4313332694 type Work @default.
- W4313332694 citedByCount "9" @default.
- W4313332694 countsByYear W43133326942022 @default.
- W4313332694 countsByYear W43133326942023 @default.
- W4313332694 crossrefType "journal-article" @default.
- W4313332694 hasAuthorship W4313332694A5011929536 @default.
- W4313332694 hasAuthorship W4313332694A5012136645 @default.
- W4313332694 hasAuthorship W4313332694A5038336906 @default.
- W4313332694 hasAuthorship W4313332694A5068176076 @default.
- W4313332694 hasAuthorship W4313332694A5086637212 @default.
- W4313332694 hasBestOaLocation W43133326941 @default.
- W4313332694 hasConcept C104317684 @default.
- W4313332694 hasConcept C136199206 @default.
- W4313332694 hasConcept C141231307 @default.
- W4313332694 hasConcept C143121216 @default.
- W4313332694 hasConcept C144024400 @default.
- W4313332694 hasConcept C149923435 @default.
- W4313332694 hasConcept C15151743 @default.
- W4313332694 hasConcept C182615771 @default.
- W4313332694 hasConcept C190743605 @default.