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- W4313334042 endingPage "3353" @default.
- W4313334042 startingPage "3327" @default.
- W4313334042 abstract "Magnesium (Mg) alloys have attracted a wealth of attention in orthopedic fields for their superior mechanical properties, degradability, and excellent biocompatibility. Consistently, to resolve the issues on rapid degradation, more studies are dedicated to the researches on the composition design, preparation and processing, surface modification, the degradation modes of Mg alloys. Nevertheless, the mechanisms by which Mg alloys promote bone healing remain elusive. This review gives an account of specific mechanisms on Mg alloys promoting bone healing from four aspects, immunomodulatory, angiogenesis, osteogenesis and regulation of osteoclast function. We highlight the regulation of Mg alloys on the functional status and interactions of numerous cells that are involved in bone healing, including immune cells, osteogenic-related cells, osteoclasts, endothelial cells (ECs), nerve cells, etc., and summarize the signaling pathways involved, with the aim to provide the basis and support on future investigation on mechanisms on Mg alloys driving bone regeneration. More importantly, it provides a rationale and a general new basis for the application of Mg alloys in orthopedic fields." @default.
- W4313334042 created "2023-01-06" @default.
- W4313334042 creator A5027686431 @default.
- W4313334042 creator A5030863883 @default.
- W4313334042 creator A5034967177 @default.
- W4313334042 creator A5043839950 @default.
- W4313334042 creator A5052300795 @default.
- W4313334042 creator A5054078102 @default.
- W4313334042 creator A5083381953 @default.
- W4313334042 creator A5085672892 @default.
- W4313334042 date "2022-12-01" @default.
- W4313334042 modified "2023-10-17" @default.
- W4313334042 title "Magnesium alloys for orthopedic applications:A review on the mechanisms driving bone healing" @default.
- W4313334042 cites W1188527999 @default.
- W4313334042 cites W135569227 @default.
- W4313334042 cites W1482741184 @default.
- W4313334042 cites W1487870896 @default.
- W4313334042 cites W1785602963 @default.
- W4313334042 cites W1794218823 @default.
- W4313334042 cites W1904424573 @default.
- W4313334042 cites W1907833971 @default.
- W4313334042 cites W1942809280 @default.
- W4313334042 cites W1975682654 @default.
- W4313334042 cites W1976111921 @default.
- W4313334042 cites W1980143338 @default.
- W4313334042 cites W1985202261 @default.
- W4313334042 cites W1986208755 @default.
- W4313334042 cites W1991776085 @default.
- W4313334042 cites W1993454360 @default.
- W4313334042 cites W1997778906 @default.
- W4313334042 cites W1998839841 @default.
- W4313334042 cites W2002392082 @default.
- W4313334042 cites W2002606648 @default.
- W4313334042 cites W2010643522 @default.
- W4313334042 cites W2014932842 @default.
- W4313334042 cites W2015329065 @default.
- W4313334042 cites W2021075911 @default.
- W4313334042 cites W2022434230 @default.
- W4313334042 cites W2022519377 @default.
- W4313334042 cites W2023471972 @default.
- W4313334042 cites W2036557984 @default.
- W4313334042 cites W2038847164 @default.
- W4313334042 cites W2039407261 @default.
- W4313334042 cites W2039990126 @default.
- W4313334042 cites W2041658193 @default.
- W4313334042 cites W2042253180 @default.
- W4313334042 cites W2049828715 @default.
- W4313334042 cites W2050239692 @default.
- W4313334042 cites W2050753871 @default.
- W4313334042 cites W2060882888 @default.
- W4313334042 cites W2069399162 @default.
- W4313334042 cites W2075449948 @default.
- W4313334042 cites W2080199445 @default.
- W4313334042 cites W2080916240 @default.
- W4313334042 cites W2081596239 @default.
- W4313334042 cites W2087625365 @default.
- W4313334042 cites W2093267247 @default.
- W4313334042 cites W2093898148 @default.
- W4313334042 cites W2094193542 @default.
- W4313334042 cites W2094893662 @default.
- W4313334042 cites W2114604396 @default.
- W4313334042 cites W2121016221 @default.
- W4313334042 cites W2126675210 @default.
- W4313334042 cites W2131116668 @default.
- W4313334042 cites W2145463329 @default.
- W4313334042 cites W2147909568 @default.
- W4313334042 cites W2166635199 @default.
- W4313334042 cites W2182798903 @default.
- W4313334042 cites W2184226854 @default.
- W4313334042 cites W2189718565 @default.
- W4313334042 cites W2213948171 @default.
- W4313334042 cites W2215626906 @default.
- W4313334042 cites W2224117614 @default.
- W4313334042 cites W2225772248 @default.
- W4313334042 cites W2291522985 @default.
- W4313334042 cites W2293356454 @default.
- W4313334042 cites W2295412260 @default.
- W4313334042 cites W2310263653 @default.
- W4313334042 cites W2310539800 @default.
- W4313334042 cites W2311665571 @default.
- W4313334042 cites W2328003959 @default.
- W4313334042 cites W2339605828 @default.
- W4313334042 cites W2343832243 @default.
- W4313334042 cites W2345632305 @default.
- W4313334042 cites W2347165177 @default.
- W4313334042 cites W2417361904 @default.
- W4313334042 cites W2418599019 @default.
- W4313334042 cites W2462081043 @default.
- W4313334042 cites W2471475697 @default.
- W4313334042 cites W2510993966 @default.
- W4313334042 cites W2516845446 @default.
- W4313334042 cites W2520287758 @default.
- W4313334042 cites W2530438934 @default.
- W4313334042 cites W2531033747 @default.
- W4313334042 cites W2538408160 @default.
- W4313334042 cites W2553610650 @default.
- W4313334042 cites W2558810585 @default.
- W4313334042 cites W2559797634 @default.