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- W4313339199 abstract "Abstract Evidence exists that C is involved in the coagulation process (Zimmerman et al., J. Exp. Med., No. 6, 1971). It has been reported that C3 (β1C/β1A) is significantly depressed in most patients with DIC (Tomar et al., Thromb. Diath. Haemorrh., 3: 27, 1972). In the present study C3 and C4 were quantitated by single radial immunodiffusion in the plasma of patients suffering mostly from severe septic and traumatic conditions with and without shock. Examinations including detailed coagulation studies were performed on 30 selected patients and 14 showed characteristic signs of DIC. C3 was markedly diminished in 13, C4 in 9 of the 14 DIC patients. In patients with septicemia but without DIC, a larger variation of results was found. In this group, depressions of C3 were observed in 6, and of C4 in 3 of 10 cases and seemed to occur more frequently when the condition was complicated by shock." @default.
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- W4313339199 date "1973-07-01" @default.
- W4313339199 modified "2023-09-29" @default.
- W4313339199 title "Quantitation of C3 and C4 in Patients with Severe Infections or Trauma with and Without Disseminated Intravascular Coagulation (DIC)" @default.
- W4313339199 doi "https://doi.org/10.4049/jimmunol.111.1.312.a" @default.
- W4313339199 hasPublicationYear "1973" @default.
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