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• W4313340280 startingPage "e00303" @default.
• W4313340280 abstract "Clinical laboratory errors have a great impact on patient safety and treatment. Although specimen rejections result in longer turnaround times and increased health-care costs, different studies present inconsistent findings. Therefore, the study aimed to determine the pooled prevalence of blood specimen rejection in clinical laboratory.Electronic databases including MEDLINE, PubMed, EMBASE, HINARI, Cochrane Library, Google Scholar, and Science Direct were comprehensively searched. Articles were screened and the data extracted independently by authors. Publication bias was checked by funnel-plots and Egger's statistical test. Pooled prevalence was estimated using a random-effects model. The I2 statistical test were performed to assess heterogeneity. The possible sources of heterogeneity were analyzed through subgroup and sensitivity analysis.Total of 26 articles with 16,118,499 blood sample requests were included in the meta-analysis. The pooled prevalence of blood specimen rejection in the clinical laboratory was 1.99% (95% CI: 1.73, 2.25). Subgroup analysis showed that, the highest prevalence of specimen rejection was observed in Asia [2.82% (95%CI: 2.21, 3.43)] and lowest in America [0.55% (95%CI: 0.27, 0.82)]. The leading cause of blood specimen rejection in clinical laboratories were clotted specimen (32.23% (95%CI: 21.02, 43.43)), hemolysis (22.87% (95%CI: 16.72, 29.02)), insufficient volume (22.81% (95%CI: 16.75, 28.87)), and labelling errors (7.31% (95%CI: 6.12, 8.58)).The pooled prevalence of blood specimen rejection rate is relatively high especially in developing regions. Therefore, proper training for specimen collectors, compliance with good laboratory practices specific to specimen collection, transportation, and preparation is required to reduce the rejection rate." @default.
• W4313340280 created "2023-01-06" @default.
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• W4313340280 date "2023-01-01" @default.
• W4313340280 modified "2023-09-30" @default.
• W4313340280 title "Blood specimen rejection rate in clinical laboratory: A systematic review and meta-analysis" @default.
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• W4313340280 doi "https://doi.org/10.1016/j.plabm.2022.e00303" @default.
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