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- W4313341401 abstract "Abstract Sir: Drs. Gershwin, Steinberg et al. recently reported in the Journal of Immunology (1) data bearing on the evaluation of the mouse rosette assay for thymic hormone. These authors confirmed many of our previous findings on this matter, including: 1) the difference in sensitivity to azathioprine and anti-θ serum of spontaneous spleen rosette-forming cells (RFC)1 from normal and nude mice (2); 2) the restoration of normal azathioprine sensitivity in nude RFC after in vitro treatment with thymosin or normal mouse serum (3, 4) and 3) the age-dependent decrease in the serum level of thymic hormone in normal mice at the age of 6 months, and in NZB mice, prematurely, at the age of 2 months (5). This latter fact led us to the idea that NZB mice present an early cessation of thymic hormone secretion, which might be involved in pathogenesis of their autoimmune disease (5)." @default.
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- W4313341401 date "1976-06-01" @default.
- W4313341401 modified "2023-10-16" @default.
- W4313341401 title "Absence of demonstrable effects of thymocytotoxic antibodies on serum thymic hormone level in NZB mice" @default.
- W4313341401 doi "https://doi.org/10.4049/jimmunol.116.6.1756" @default.
- W4313341401 hasPublicationYear "1976" @default.
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