Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313346314> ?p ?o ?g. }
- W4313346314 endingPage "115080" @default.
- W4313346314 startingPage "115080" @default.
- W4313346314 abstract "Nicotinamide phosphoribosyl transferase (NAMPT) has been regarded as an attractive target for cancer therapy. However, there is a lack of chemical tools for real-time visualization and detection of NAMPT. Herein, the first fluorescent and theranostic probes were designed for imaging NAMPT, which had dual functions of diagnosis and treatment. The designed probes possessed good affinity and environmental sensitivity to NAMPT with a turn-on mechanism and were successfully applied in fluorescence detecting and imaging of NAMPT at the level of living cells and tissue sections. They also effectively inhibited tumor cell proliferation and arrested cell cycle at the G2 phase. These fluorescent probes enabled detection and visualization of NAMPT, representing effective chemical tools for the pathological diagnosis and treatment of cancer." @default.
- W4313346314 created "2023-01-06" @default.
- W4313346314 creator A5021315052 @default.
- W4313346314 creator A5032790556 @default.
- W4313346314 creator A5057853505 @default.
- W4313346314 creator A5064491215 @default.
- W4313346314 creator A5067500986 @default.
- W4313346314 creator A5082139203 @default.
- W4313346314 creator A5082494084 @default.
- W4313346314 date "2023-02-01" @default.
- W4313346314 modified "2023-10-03" @default.
- W4313346314 title "Fluorescent and theranostic probes for imaging nicotinamide phosphoribosyl transferase (NAMPT)" @default.
- W4313346314 cites W1999564272 @default.
- W4313346314 cites W2045695123 @default.
- W4313346314 cites W2045763194 @default.
- W4313346314 cites W2050456292 @default.
- W4313346314 cites W2053467025 @default.
- W4313346314 cites W2061580371 @default.
- W4313346314 cites W2064481140 @default.
- W4313346314 cites W2083255026 @default.
- W4313346314 cites W2103542843 @default.
- W4313346314 cites W2119700304 @default.
- W4313346314 cites W2135076718 @default.
- W4313346314 cites W2144424664 @default.
- W4313346314 cites W2169627739 @default.
- W4313346314 cites W2174179366 @default.
- W4313346314 cites W2312358918 @default.
- W4313346314 cites W2343462384 @default.
- W4313346314 cites W2397126689 @default.
- W4313346314 cites W2469494794 @default.
- W4313346314 cites W2511525462 @default.
- W4313346314 cites W2543570310 @default.
- W4313346314 cites W2597062310 @default.
- W4313346314 cites W2598437826 @default.
- W4313346314 cites W2756054102 @default.
- W4313346314 cites W2758067903 @default.
- W4313346314 cites W2775071408 @default.
- W4313346314 cites W2775486301 @default.
- W4313346314 cites W2791673616 @default.
- W4313346314 cites W2792870066 @default.
- W4313346314 cites W2904813088 @default.
- W4313346314 cites W2917022358 @default.
- W4313346314 cites W2941157636 @default.
- W4313346314 cites W2971370669 @default.
- W4313346314 cites W2995771616 @default.
- W4313346314 cites W2997890859 @default.
- W4313346314 cites W3007543759 @default.
- W4313346314 cites W3126718841 @default.
- W4313346314 cites W4206643763 @default.
- W4313346314 cites W4282013086 @default.
- W4313346314 doi "https://doi.org/10.1016/j.ejmech.2022.115080" @default.
- W4313346314 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36608458" @default.
- W4313346314 hasPublicationYear "2023" @default.
- W4313346314 type Work @default.
- W4313346314 citedByCount "0" @default.
- W4313346314 crossrefType "journal-article" @default.
- W4313346314 hasAuthorship W4313346314A5021315052 @default.
- W4313346314 hasAuthorship W4313346314A5032790556 @default.
- W4313346314 hasAuthorship W4313346314A5057853505 @default.
- W4313346314 hasAuthorship W4313346314A5064491215 @default.
- W4313346314 hasAuthorship W4313346314A5067500986 @default.
- W4313346314 hasAuthorship W4313346314A5082139203 @default.
- W4313346314 hasAuthorship W4313346314A5082494084 @default.
- W4313346314 hasConcept C121332964 @default.
- W4313346314 hasConcept C12554922 @default.
- W4313346314 hasConcept C181199279 @default.
- W4313346314 hasConcept C185592680 @default.
- W4313346314 hasConcept C2779728014 @default.
- W4313346314 hasConcept C2780391879 @default.
- W4313346314 hasConcept C502942594 @default.
- W4313346314 hasConcept C55493867 @default.
- W4313346314 hasConcept C57477423 @default.
- W4313346314 hasConcept C62520636 @default.
- W4313346314 hasConcept C75520062 @default.
- W4313346314 hasConcept C86803240 @default.
- W4313346314 hasConcept C91881484 @default.
- W4313346314 hasConceptScore W4313346314C121332964 @default.
- W4313346314 hasConceptScore W4313346314C12554922 @default.
- W4313346314 hasConceptScore W4313346314C181199279 @default.
- W4313346314 hasConceptScore W4313346314C185592680 @default.
- W4313346314 hasConceptScore W4313346314C2779728014 @default.
- W4313346314 hasConceptScore W4313346314C2780391879 @default.
- W4313346314 hasConceptScore W4313346314C502942594 @default.
- W4313346314 hasConceptScore W4313346314C55493867 @default.
- W4313346314 hasConceptScore W4313346314C57477423 @default.
- W4313346314 hasConceptScore W4313346314C62520636 @default.
- W4313346314 hasConceptScore W4313346314C75520062 @default.
- W4313346314 hasConceptScore W4313346314C86803240 @default.
- W4313346314 hasConceptScore W4313346314C91881484 @default.
- W4313346314 hasFunder F4320321001 @default.
- W4313346314 hasFunder F4320335777 @default.
- W4313346314 hasLocation W43133463141 @default.
- W4313346314 hasLocation W43133463142 @default.
- W4313346314 hasOpenAccess W4313346314 @default.
- W4313346314 hasPrimaryLocation W43133463141 @default.
- W4313346314 hasRelatedWork W1218434330 @default.
- W4313346314 hasRelatedWork W1965358923 @default.
- W4313346314 hasRelatedWork W2015377162 @default.