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- W4313352910 abstract "Diabetic macular edema (DME) is an important complication of diabetic retinopathy resulting in moderate vision loss in patients with diabetes mellitus. Inflammatory mediators, in a setting of chronic hyperglycemia, cause breakdown of blood–retinal barrier and alteration of vascular permeability resulting in DME. Intravitreal steroids provide a useful management option in a subset of patients with DME where inflammation is the predominant pathway. Dexamethasone implant (Ozurdex®; Allergan, Inc., Irvine, CA, United States) has become the most widely used intravitreal steroid following its FDA approval in 2014. Sustained release of drug for long interval of time enables better response to therapy and less frequent dosing intervals. In this chapter, we shall discuss the possible role of inflammation in DME as well as role of dexamethasone implant in the management of DME." @default.
- W4313352910 created "2023-01-06" @default.
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- W4313352910 date "2022-01-01" @default.
- W4313352910 modified "2023-09-28" @default.
- W4313352910 title "Dexamethasone Implant in Diabetic Macular Edema" @default.
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- W4313352910 doi "https://doi.org/10.1007/978-981-19-7307-9_11" @default.
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