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- W4313355215 abstract "Background Lower gastrointestinal bleeding (LGIB) is common in inpatient and outpatient settings; however, there are limited studies on the clinical characteristics and patient outcomes of those with hospital-acquired LGIB. Methods We performed a retrospective cohort study of patients with hospital-acquired LGIB who underwent colonoscopy during hospitalization between January 2017 and December 2021. We described the clinical characteristics, etiology, and clinical outcomes of patients stratified as those undergoing colonoscopy within 24 hours from haematochezia onset (early colonoscopy group) or after 24 hours from onset (late colonoscopy group). We used multivariable logistic regression to identify factors associated with endoscopic intervention in the early and late colonoscopy groups. Results Of the 272 patients included, the median age was 79 years (interquartile range: 72-85 years), 153 (56%) were bedridden, and 172 (63%) had hypoalbuminemia. The most frequent etiology was rectal ulcer (101 cases, 37%), whereas 7 (2.6%) had diverticular bleeding. The endoscopic intervention was performed on 16.7% and 7.9% of early and late colonoscopy patients. There were more patients with both non-severe and severe rebleeding in the early colonoscopy group (16% and 12%, respectively) than in the late colonoscopy group (11% and 6.5%, respectively). Colonoscopy-on-worktime was the only factor independently associated with a higher occurrence of endoscopic intervention. Conclusions In our sample, very old patients with hospital-acquired LGIB required endoscopy mainly due to rectal ulcers. Further studies will be necessary to investigate the differences between community-acquired LGIB and hospital-acquired LGIB and the optimal timing of colonoscopy for these patients." @default.
- W4313355215 created "2023-01-06" @default.
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- W4313355215 date "2022-12-17" @default.
- W4313355215 modified "2023-09-30" @default.
- W4313355215 title "Clinical Characteristics and Outcomes of Hospital-Acquired Lower Gastrointestinal Bleeding: A Single Centre Retrospective Cohort Study" @default.
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- W4313355215 doi "https://doi.org/10.7759/cureus.32651" @default.
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