Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313356881> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W4313356881 endingPage "63.16" @default.
- W4313356881 startingPage "63.16" @default.
- W4313356881 abstract "Abstract Cystic echinococcosis is a neglected parasitic disease all around the world, which due to the infection of Echinococcus granulosus larva in the intermediate host, such as human and sheep. The liver is the major battlefield of the host defends against the parasite, and many immune response and metabolism happened here. This article is aimed to study the gene expression of liver participates in this process, by use of C57 as the experimental animal model and microarray technology. The results showed that 77 genes were up-regulated and 17 genes were down-regulated in the liver adjacent to the parasite lesion. The bioinformatics analysis showed that the most up regulated genes were correlated with immune response process, signal transduction pathway and protein degradation, and down regulated genes were related to metabolism and cell cycle. Immunoglobulin related genes were predicted participation in many important pathways (Fc epsilon RI signaling pathway, primary immunodeficiency, allograft rejection). In addition, transform growth factor receptor 2 was found increased expression in the infected C57BL/6 liver tissue by microarray (2.29-fold) and RT-qPCR (21.4-fold). Quantitative RT-PCR analysis of a random selection of 18 genes confirmed the reliability of the microarray data. Our results provide a hint that immunoglobulin relative genes might participate the interplay between the host and parasite." @default.
- W4313356881 created "2023-01-06" @default.
- W4313356881 creator A5028203364 @default.
- W4313356881 creator A5044301848 @default.
- W4313356881 creator A5057735128 @default.
- W4313356881 creator A5064711465 @default.
- W4313356881 creator A5081488669 @default.
- W4313356881 date "2015-05-01" @default.
- W4313356881 modified "2023-10-16" @default.
- W4313356881 title "Immunoglobulin relative genes were up-regulated in the liver of cystic echinococcosis mouse (MPF2P.757)" @default.
- W4313356881 doi "https://doi.org/10.4049/jimmunol.194.supp.63.16" @default.
- W4313356881 hasPublicationYear "2015" @default.
- W4313356881 type Work @default.
- W4313356881 citedByCount "0" @default.
- W4313356881 crossrefType "journal-article" @default.
- W4313356881 hasAuthorship W4313356881A5028203364 @default.
- W4313356881 hasAuthorship W4313356881A5044301848 @default.
- W4313356881 hasAuthorship W4313356881A5057735128 @default.
- W4313356881 hasAuthorship W4313356881A5064711465 @default.
- W4313356881 hasAuthorship W4313356881A5081488669 @default.
- W4313356881 hasConcept C104317684 @default.
- W4313356881 hasConcept C127716648 @default.
- W4313356881 hasConcept C136764020 @default.
- W4313356881 hasConcept C150194340 @default.
- W4313356881 hasConcept C159654299 @default.
- W4313356881 hasConcept C165901193 @default.
- W4313356881 hasConcept C18431079 @default.
- W4313356881 hasConcept C186836561 @default.
- W4313356881 hasConcept C203014093 @default.
- W4313356881 hasConcept C2777028278 @default.
- W4313356881 hasConcept C2779452502 @default.
- W4313356881 hasConcept C2780340127 @default.
- W4313356881 hasConcept C41008148 @default.
- W4313356881 hasConcept C54355233 @default.
- W4313356881 hasConcept C62478195 @default.
- W4313356881 hasConcept C71928629 @default.
- W4313356881 hasConcept C8415881 @default.
- W4313356881 hasConcept C86803240 @default.
- W4313356881 hasConcept C8891405 @default.
- W4313356881 hasConcept C90856448 @default.
- W4313356881 hasConceptScore W4313356881C104317684 @default.
- W4313356881 hasConceptScore W4313356881C127716648 @default.
- W4313356881 hasConceptScore W4313356881C136764020 @default.
- W4313356881 hasConceptScore W4313356881C150194340 @default.
- W4313356881 hasConceptScore W4313356881C159654299 @default.
- W4313356881 hasConceptScore W4313356881C165901193 @default.
- W4313356881 hasConceptScore W4313356881C18431079 @default.
- W4313356881 hasConceptScore W4313356881C186836561 @default.
- W4313356881 hasConceptScore W4313356881C203014093 @default.
- W4313356881 hasConceptScore W4313356881C2777028278 @default.
- W4313356881 hasConceptScore W4313356881C2779452502 @default.
- W4313356881 hasConceptScore W4313356881C2780340127 @default.
- W4313356881 hasConceptScore W4313356881C41008148 @default.
- W4313356881 hasConceptScore W4313356881C54355233 @default.
- W4313356881 hasConceptScore W4313356881C62478195 @default.
- W4313356881 hasConceptScore W4313356881C71928629 @default.
- W4313356881 hasConceptScore W4313356881C8415881 @default.
- W4313356881 hasConceptScore W4313356881C86803240 @default.
- W4313356881 hasConceptScore W4313356881C8891405 @default.
- W4313356881 hasConceptScore W4313356881C90856448 @default.
- W4313356881 hasIssue "1_Supplement" @default.
- W4313356881 hasLocation W43133568811 @default.
- W4313356881 hasOpenAccess W4313356881 @default.
- W4313356881 hasPrimaryLocation W43133568811 @default.
- W4313356881 hasRelatedWork W1531528770 @default.
- W4313356881 hasRelatedWork W1983994322 @default.
- W4313356881 hasRelatedWork W2006024165 @default.
- W4313356881 hasRelatedWork W2053053668 @default.
- W4313356881 hasRelatedWork W2364061485 @default.
- W4313356881 hasRelatedWork W2415025170 @default.
- W4313356881 hasRelatedWork W2900947575 @default.
- W4313356881 hasRelatedWork W2998765584 @default.
- W4313356881 hasRelatedWork W3032874291 @default.
- W4313356881 hasRelatedWork W74695042 @default.
- W4313356881 hasVolume "194" @default.
- W4313356881 isParatext "false" @default.
- W4313356881 isRetracted "false" @default.
- W4313356881 workType "article" @default.