Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313358191> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W4313358191 endingPage "400" @default.
- W4313358191 startingPage "393" @default.
- W4313358191 abstract "Objective: Previous studies have shown a higher prevalence of non-alcoholic fatty liver disease (NAFLD) among patients with type 2 diabetes mellitus (T2DM), and NAFLD itself is a risk factor for cardiovascular diseases (CVD). With both NAFLD and T2DM, there is a vicious circle of disease worsening, with one disease aggravating the development and progression of the other, thereby predisposing to early CVD events. Hence, we aimed to study the association between hepatobiliary status and cardiometabolic risk among T2DM patients. Material and methods: Eighty two patients with T2DM without any established liver and cardiac disease were recruited for the study. Routine biochemical parameters were measured by an autoanalyzer. Parameters such as triglyceride glucose index (TyG index), lipid pentad index, fatty liver disease index (FLDI) etc. were calculated using the established formulas. HbA1c was estimated using Biorad D10 autoanalyzer. Apolipoprotein B (Apo-B), Apo-A, lipoprotein (a) [Lp(a)], insulin, C-peptide were analyzed using ELISA. Results: Significant positive correlation was seen between cardiometabolic risk biomarkers and hepatobiliary biomarkers and significant negative correlation with total bilirubin and De-Ritis ratio. Through stepwise regression, FLDI was found to be a significant factor in the prediction of lipid pentad index (LPI). LPI, TyG index, FLDI were able to differentiate patients with T2DM based on the gold standard HbA1c values for T2DM diagnosis. Conclusions: Increase in hepatobiliary dysfunction contributes to increased CVD risk in T2DM patients. This study highlights the need for collaborative actions of diabetologists and hepatologists in identifying the people with NAFLD among T2DM patients, who should be targeted with intensive therapy to decrease their risk of future CVD events." @default.
- W4313358191 created "2023-01-06" @default.
- W4313358191 creator A5060569792 @default.
- W4313358191 creator A5075072862 @default.
- W4313358191 creator A5079917691 @default.
- W4313358191 creator A5080652431 @default.
- W4313358191 creator A5087136172 @default.
- W4313358191 date "2022-12-28" @default.
- W4313358191 modified "2023-09-30" @default.
- W4313358191 title "Assessment of Hepatobiliary Status and Cardiometabolic Risk Markers among Type 2 Diabetes Mellitus Patients. A Cross-Sectional Study" @default.
- W4313358191 doi "https://doi.org/10.5603/dk.a2022.0058" @default.
- W4313358191 hasPublicationYear "2022" @default.
- W4313358191 type Work @default.
- W4313358191 citedByCount "0" @default.
- W4313358191 crossrefType "journal-article" @default.
- W4313358191 hasAuthorship W4313358191A5060569792 @default.
- W4313358191 hasAuthorship W4313358191A5075072862 @default.
- W4313358191 hasAuthorship W4313358191A5079917691 @default.
- W4313358191 hasAuthorship W4313358191A5080652431 @default.
- W4313358191 hasAuthorship W4313358191A5087136172 @default.
- W4313358191 hasBestOaLocation W43133581911 @default.
- W4313358191 hasConcept C126322002 @default.
- W4313358191 hasConcept C134018914 @default.
- W4313358191 hasConcept C170094789 @default.
- W4313358191 hasConcept C2777180221 @default.
- W4313358191 hasConcept C2778772119 @default.
- W4313358191 hasConcept C2779134260 @default.
- W4313358191 hasConcept C2910068830 @default.
- W4313358191 hasConcept C50440223 @default.
- W4313358191 hasConcept C555293320 @default.
- W4313358191 hasConcept C71924100 @default.
- W4313358191 hasConcept C90924648 @default.
- W4313358191 hasConceptScore W4313358191C126322002 @default.
- W4313358191 hasConceptScore W4313358191C134018914 @default.
- W4313358191 hasConceptScore W4313358191C170094789 @default.
- W4313358191 hasConceptScore W4313358191C2777180221 @default.
- W4313358191 hasConceptScore W4313358191C2778772119 @default.
- W4313358191 hasConceptScore W4313358191C2779134260 @default.
- W4313358191 hasConceptScore W4313358191C2910068830 @default.
- W4313358191 hasConceptScore W4313358191C50440223 @default.
- W4313358191 hasConceptScore W4313358191C555293320 @default.
- W4313358191 hasConceptScore W4313358191C71924100 @default.
- W4313358191 hasConceptScore W4313358191C90924648 @default.
- W4313358191 hasIssue "6" @default.
- W4313358191 hasLocation W43133581911 @default.
- W4313358191 hasOpenAccess W4313358191 @default.
- W4313358191 hasPrimaryLocation W43133581911 @default.
- W4313358191 hasRelatedWork W1055670285 @default.
- W4313358191 hasRelatedWork W1785907357 @default.
- W4313358191 hasRelatedWork W1966504330 @default.
- W4313358191 hasRelatedWork W1979139803 @default.
- W4313358191 hasRelatedWork W2164650015 @default.
- W4313358191 hasRelatedWork W2363455484 @default.
- W4313358191 hasRelatedWork W2377830747 @default.
- W4313358191 hasRelatedWork W2748952813 @default.
- W4313358191 hasRelatedWork W2973263109 @default.
- W4313358191 hasRelatedWork W4229452857 @default.
- W4313358191 hasVolume "11" @default.
- W4313358191 isParatext "false" @default.
- W4313358191 isRetracted "false" @default.
- W4313358191 workType "article" @default.