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• W4313362078 startingPage "604" @default.
• W4313362078 abstract "Neurodegenerative diseases have acquired the status of one of the leading causes of death in developed countries, which requires creating new model systems capable of accurately reproducing the mechanisms underlying these pathologies. Here we analyzed modern model systems and their contribution to the solution of unexplored manifestations of neuropathological processes. Each model has unique properties that make it the optimal tool for modeling certain aspects of neurodegenerative disorders. We concluded that to optimize research, it is necessary to combine models into complexes that include organisms and artificial systems of different organizational levels. Such complexes can be organized in two ways. The first method can be described as step by step, where each model for studying a certain characteristic is a separate step that allows using the information obtained in the modeling process for the gradual study of increasingly complex processes in subsequent models. The second way is a 'network' approach. Studies are carried out with several types of models simultaneously, and experiments with each specific type are adjusted in conformity with the data obtained from other models. In our opinion, the 'network' approach to combining individual model systems seems more promising for fundamental biology as well as diagnostics and therapy." @default.
• W4313362078 created "2023-01-06" @default.
• W4313362078 creator A5003636414 @default.
• W4313362078 creator A5020767806 @default.
• W4313362078 creator A5047780760 @default.
• W4313362078 creator A5062338777 @default.
• W4313362078 creator A5067866969 @default.
• W4313362078 date "2022-12-29" @default.
• W4313362078 modified "2023-09-27" @default.
• W4313362078 title "Modeling of Neurodegenerative Diseases: ‘Step by Step’ and ‘Network’ Organization of the Complexes of Model Systems" @default.
• W4313362078 cites W134197426 @default.
• W4313362078 cites W1523338791 @default.
• W4313362078 cites W1577837690 @default.
• W4313362078 cites W1763258797 @default.
• W4313362078 cites W1780615788 @default.
• W4313362078 cites W1862266358 @default.
• W4313362078 cites W1966923623 @default.
• W4313362078 cites W1979562942 @default.
• W4313362078 cites W1983069042 @default.
• W4313362078 cites W1990308695 @default.
• W4313362078 cites W1997246422 @default.
• W4313362078 cites W1997446653 @default.
• W4313362078 cites W2001764336 @default.
• W4313362078 cites W2003618511 @default.
• W4313362078 cites W2005389791 @default.
• W4313362078 cites W2006688209 @default.
• W4313362078 cites W2013765317 @default.
• W4313362078 cites W2025793780 @default.
• W4313362078 cites W2027028232 @default.
• W4313362078 cites W2030341400 @default.
• W4313362078 cites W2031880534 @default.
• W4313362078 cites W2034517775 @default.
• W4313362078 cites W2034578928 @default.
• W4313362078 cites W2041935553 @default.
• W4313362078 cites W2049956841 @default.
• W4313362078 cites W2055373527 @default.
• W4313362078 cites W2057293794 @default.
• W4313362078 cites W2057764483 @default.
• W4313362078 cites W2058723245 @default.
• W4313362078 cites W2067692987 @default.
• W4313362078 cites W2069350252 @default.
• W4313362078 cites W2072296425 @default.
• W4313362078 cites W2074555768 @default.
• W4313362078 cites W2084561728 @default.
• W4313362078 cites W2092721181 @default.
• W4313362078 cites W2094478098 @default.
• W4313362078 cites W2114371461 @default.
• W4313362078 cites W2119284420 @default.
• W4313362078 cites W2120708642 @default.
• W4313362078 cites W2132442335 @default.
• W4313362078 cites W2138774341 @default.
• W4313362078 cites W2147881874 @default.
• W4313362078 cites W2150656456 @default.
• W4313362078 cites W2150860634 @default.
• W4313362078 cites W2151521848 @default.
• W4313362078 cites W2152165298 @default.
• W4313362078 cites W2154758277 @default.
• W4313362078 cites W2160938187 @default.
• W4313362078 cites W2161765631 @default.
• W4313362078 cites W2189355713 @default.
• W4313362078 cites W2263783515 @default.
• W4313362078 cites W2323997943 @default.
• W4313362078 cites W2324660492 @default.
• W4313362078 cites W2427722095 @default.
• W4313362078 cites W2479362027 @default.
• W4313362078 cites W2528438579 @default.
• W4313362078 cites W2561721115 @default.
• W4313362078 cites W2592067246 @default.
• W4313362078 cites W2606065361 @default.
• W4313362078 cites W2611631440 @default.
• W4313362078 cites W2763935949 @default.
• W4313362078 cites W2765457511 @default.
• W4313362078 cites W2766853085 @default.
• W4313362078 cites W2769118369 @default.
• W4313362078 cites W2774212947 @default.
• W4313362078 cites W2788953364 @default.
• W4313362078 cites W2789933553 @default.
• W4313362078 cites W2791216165 @default.
• W4313362078 cites W2793882579 @default.
• W4313362078 cites W2799817815 @default.
• W4313362078 cites W2800767933 @default.
• W4313362078 cites W2887701645 @default.
• W4313362078 cites W2889749509 @default.
• W4313362078 cites W2891411797 @default.
• W4313362078 cites W2898018533 @default.
• W4313362078 cites W2941080670 @default.
• W4313362078 cites W2949125436 @default.
• W4313362078 cites W2952747170 @default.
• W4313362078 cites W2953534538 @default.
• W4313362078 cites W2967701189 @default.
• W4313362078 cites W2969563383 @default.
• W4313362078 cites W2999018057 @default.
• W4313362078 cites W3010304244 @default.
• W4313362078 cites W3017129299 @default.
• W4313362078 cites W3026622728 @default.
• W4313362078 cites W3027193583 @default.
• W4313362078 cites W3092656857 @default.
• W4313362078 cites W3095298869 @default.

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