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- W4313362449 endingPage "608" @default.
- W4313362449 startingPage "608" @default.
- W4313362449 abstract "Mitochondria are the key biological generators of eukaryotic cells, controlling the energy supply while providing many important biosynthetic intermediates. Mitochondria act as a dynamic, functionally and structurally interconnected network hub closely integrated with other cellular compartments via biomembrane systems, transmitting biological information by shuttling between cells and tissues. Defects and dysregulation of mitochondrial functions are critically involved in pathological mechanisms contributing to aging, cancer, inflammation, neurodegenerative diseases, and other severe human diseases. Mediating and rejuvenating the mitochondria may therefore be of significant benefit to prevent, reverse, and even treat such pathological conditions in patients. The goal of this review is to present the most advanced strategies using mitochondria to manage such disorders and to further explore innovative approaches in the field of human mitochondria-based therapies." @default.
- W4313362449 created "2023-01-06" @default.
- W4313362449 creator A5028522969 @default.
- W4313362449 creator A5039286395 @default.
- W4313362449 creator A5056594389 @default.
- W4313362449 creator A5083684200 @default.
- W4313362449 date "2022-12-29" @default.
- W4313362449 modified "2023-10-12" @default.
- W4313362449 title "Advances in Human Mitochondria-Based Therapies" @default.
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