FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313366898> ?p ?o ?g. }

• W4313366898 abstract "Abstract There is a great demand for developing and demonstrating novel disinfection technologies for protection against various pathogenic viruses and bacteria. In this context, ultraviolet (UV) irradiation offers an effective and convenient method for the inactivation of pathogenic microorganisms. The quantitative evaluation of the efficacy of UV sterilization relies on the simple time-dose reciprocity law proposed by Bunsen-Roscoe. However, the inactivation rate constants reported in the literature vary widely, even at the same dose and wavelength of irradiation. Thus, it is likely that the physical mechanism of UV inactivation cannot be described by the simple time-dose reciprocity law but requires a secondary inactivation process, which must be identified to clarify the scientific basis. In this paper, we conducted a UV inactivation experiment with Escherichia coli at the same dose but with different irradiances and irradiation durations, varying the irradiance by two to three orders of magnitude. We showed that the efficacy of inactivation obtained by UV-light emitting diode irradiation differs significantly by one order of magnitude at the same dose but different irradiances at a fixed wavelength. To explain this, we constructed a stochastic model introducing a second inactivation rate, such as that due to reactive oxygen species (ROS) that contribute to DNA and/or protein damage, together with the fluence-based UV inactivation rate. By solving the differential equations based on this model, the efficacy of inactivation as a function of the irradiance and irradiation duration under the same UV dose conditions was clearly elucidated. The proposed model clearly shows that at least two inactivation rates are involved in UV inactivation, where the generally used UV inactivation rate does not depend on the irradiance, but the inactivation rate due to ROS does depend on the irradiance. We conclude that the UV inactivation results obtained to date were simply fitted by one inactivation rate that superimposed these two inactivation rates. The effectiveness of long-term UV irradiation at a low irradiance but the same dose provides useful information for future disinfection technologies such as the disinfection of large spaces, for example, hospital rooms using UV light, because it can reduce the radiation dose and its risk to the human body." @default.
• W4313366898 created "2023-01-06" @default.
• W4313366898 creator A5007519585 @default.
• W4313366898 creator A5018313360 @default.
• W4313366898 creator A5047713672 @default.
• W4313366898 creator A5058282158 @default.
• W4313366898 creator A5080605076 @default.
• W4313366898 date "2022-12-30" @default.
• W4313366898 modified "2023-10-18" @default.
• W4313366898 title "Time-dose reciprocity mechanism for the inactivation of Escherichia coli explained by a stochastic process with two inactivation effects" @default.
• W4313366898 cites W1142053625 @default.
• W4313366898 cites W1541385703 @default.
• W4313366898 cites W1858486969 @default.
• W4313366898 cites W1926950498 @default.
• W4313366898 cites W1973160639 @default.
• W4313366898 cites W1975241594 @default.
• W4313366898 cites W2026743476 @default.
• W4313366898 cites W2029816243 @default.
• W4313366898 cites W2035822029 @default.
• W4313366898 cites W2055876670 @default.
• W4313366898 cites W2059648243 @default.
• W4313366898 cites W2067139494 @default.
• W4313366898 cites W2069183832 @default.
• W4313366898 cites W2074703564 @default.
• W4313366898 cites W2098280127 @default.
• W4313366898 cites W2105794386 @default.
• W4313366898 cites W2106720111 @default.
• W4313366898 cites W2175656610 @default.
• W4313366898 cites W2180589872 @default.
• W4313366898 cites W2271725715 @default.
• W4313366898 cites W2284677245 @default.
• W4313366898 cites W2315364905 @default.
• W4313366898 cites W2328967395 @default.
• W4313366898 cites W2417319027 @default.
• W4313366898 cites W2488528762 @default.
• W4313366898 cites W2549992120 @default.
• W4313366898 cites W2606757801 @default.
• W4313366898 cites W2756366661 @default.
• W4313366898 cites W2768781487 @default.
• W4313366898 cites W2893413493 @default.
• W4313366898 cites W2897773333 @default.
• W4313366898 cites W2944196887 @default.
• W4313366898 cites W2946961439 @default.
• W4313366898 cites W2950772276 @default.
• W4313366898 cites W3034395227 @default.
• W4313366898 cites W3043776404 @default.
• W4313366898 cites W3088928220 @default.
• W4313366898 cites W3093078042 @default.
• W4313366898 cites W3094301563 @default.
• W4313366898 cites W3123568420 @default.
• W4313366898 cites W3152601155 @default.
• W4313366898 cites W3166824185 @default.
• W4313366898 cites W3211340444 @default.
• W4313366898 cites W4224942235 @default.
• W4313366898 cites W4241128618 @default.
• W4313366898 doi "https://doi.org/10.1038/s41598-022-26783-x" @default.
• W4313366898 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36585428" @default.
• W4313366898 hasPublicationYear "2022" @default.
• W4313366898 type Work @default.
• W4313366898 citedByCount "0" @default.
• W4313366898 crossrefType "journal-article" @default.
• W4313366898 hasAuthorship W4313366898A5007519585 @default.
• W4313366898 hasAuthorship W4313366898A5018313360 @default.
• W4313366898 hasAuthorship W4313366898A5047713672 @default.
• W4313366898 hasAuthorship W4313366898A5058282158 @default.
• W4313366898 hasAuthorship W4313366898A5080605076 @default.
• W4313366898 hasBestOaLocation W43133668981 @default.
• W4313366898 hasConcept C104317684 @default.
• W4313366898 hasConcept C111163200 @default.
• W4313366898 hasConcept C111337013 @default.
• W4313366898 hasConcept C120665830 @default.
• W4313366898 hasConcept C121332964 @default.
• W4313366898 hasConcept C12554922 @default.
• W4313366898 hasConcept C143425029 @default.
• W4313366898 hasConcept C148761745 @default.
• W4313366898 hasConcept C148898269 @default.
• W4313366898 hasConcept C151730666 @default.
• W4313366898 hasConcept C15744967 @default.
• W4313366898 hasConcept C162324750 @default.
• W4313366898 hasConcept C169903001 @default.
• W4313366898 hasConcept C185544564 @default.
• W4313366898 hasConcept C185592680 @default.
• W4313366898 hasConcept C186060115 @default.
• W4313366898 hasConcept C2776798109 @default.
• W4313366898 hasConcept C2779343474 @default.
• W4313366898 hasConcept C2983132609 @default.
• W4313366898 hasConcept C46423501 @default.
• W4313366898 hasConcept C536366893 @default.
• W4313366898 hasConcept C547475151 @default.
• W4313366898 hasConcept C552990157 @default.
• W4313366898 hasConcept C55493867 @default.
• W4313366898 hasConcept C556758197 @default.
• W4313366898 hasConcept C62520636 @default.
• W4313366898 hasConcept C77805123 @default.
• W4313366898 hasConcept C86803240 @default.
• W4313366898 hasConceptScore W4313366898C104317684 @default.
• W4313366898 hasConceptScore W4313366898C111163200 @default.
• W4313366898 hasConceptScore W4313366898C111337013 @default.
• W4313366898 hasConceptScore W4313366898C120665830 @default.
• W4313366898 hasConceptScore W4313366898C121332964 @default.

• next