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- W4313367091 endingPage "199018" @default.
- W4313367091 startingPage "199018" @default.
- W4313367091 abstract "The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human, causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar conserved structure and sequence among distinct DENV serotypes or different flaviviruses has resulted in the occurrence of cross reaction followed by antibody-dependent enhancement (ADE). Thus far, the vaccine which can provide effective protection against infection by different DENV serotypes remains the biggest hurdle to overcome. Therefore, deep investigation is crucial for the potent and effective therapeutic drugs development. In addition, the cross-reactivity of flaviviruses that leads to false diagnosis in clinical settings could result to delay proper intervention management. Thus, the accurate diagnostic with high specificity and sensitivity is highly required to provide prompt diagnosis in respect to render early treatment for DENV infected individuals. In this review, the recent development of neutralizing antibodies, antiviral agents, and vaccine candidates in therapeutic platform for DENV infection will be discussed. Moreover, the discovery of antigenic cryptic epitopes, principle of molecular mimicry, and application of single-chain or single-domain antibodies towards DENV will also be presented." @default.
- W4313367091 created "2023-01-06" @default.
- W4313367091 creator A5015696571 @default.
- W4313367091 creator A5027580176 @default.
- W4313367091 creator A5029444898 @default.
- W4313367091 creator A5037488365 @default.
- W4313367091 creator A5060523956 @default.
- W4313367091 creator A5084653564 @default.
- W4313367091 date "2023-01-01" @default.
- W4313367091 modified "2023-10-05" @default.
- W4313367091 title "Dengue virus infection – a review of pathogenesis, vaccines, diagnosis and therapy" @default.
- W4313367091 cites W1017348960 @default.
- W4313367091 cites W1019728162 @default.
- W4313367091 cites W1020548474 @default.
- W4313367091 cites W1505989132 @default.
- W4313367091 cites W1544534947 @default.
- W4313367091 cites W1574082422 @default.
- W4313367091 cites W1630111658 @default.
- W4313367091 cites W1754276576 @default.
- W4313367091 cites W1755249617 @default.
- W4313367091 cites W1761049769 @default.
- W4313367091 cites W1834261607 @default.
- W4313367091 cites W1928251300 @default.
- W4313367091 cites W1958440227 @default.
- W4313367091 cites W1964953975 @default.
- W4313367091 cites W1966807539 @default.
- W4313367091 cites W1966927874 @default.
- W4313367091 cites W1967782833 @default.
- W4313367091 cites W1968736216 @default.
- W4313367091 cites W1968895408 @default.
- W4313367091 cites W1969968451 @default.
- W4313367091 cites W1970756887 @default.
- W4313367091 cites W1971699048 @default.
- W4313367091 cites W1974933671 @default.
- W4313367091 cites W1974942343 @default.
- W4313367091 cites W1978556120 @default.
- W4313367091 cites W1979039327 @default.
- W4313367091 cites W1983627019 @default.
- W4313367091 cites W1984085926 @default.
- W4313367091 cites W1985077614 @default.
- W4313367091 cites W1985799231 @default.
- W4313367091 cites W1985837637 @default.
- W4313367091 cites W1988789661 @default.
- W4313367091 cites W1990647489 @default.
- W4313367091 cites W1991888686 @default.
- W4313367091 cites W1996883424 @default.
- W4313367091 cites W1997791533 @default.
- W4313367091 cites W1998275580 @default.
- W4313367091 cites W2001568055 @default.
- W4313367091 cites W2005121650 @default.
- W4313367091 cites W2008216856 @default.
- W4313367091 cites W2012156061 @default.
- W4313367091 cites W2012987104 @default.
- W4313367091 cites W2013001579 @default.
- W4313367091 cites W2015130327 @default.
- W4313367091 cites W2016144978 @default.
- W4313367091 cites W2020078249 @default.
- W4313367091 cites W2022202320 @default.
- W4313367091 cites W2023422813 @default.
- W4313367091 cites W2024524568 @default.
- W4313367091 cites W2025005477 @default.
- W4313367091 cites W2025774124 @default.
- W4313367091 cites W2026939600 @default.
- W4313367091 cites W2028775614 @default.
- W4313367091 cites W2029869358 @default.
- W4313367091 cites W2031578199 @default.
- W4313367091 cites W2031997189 @default.
- W4313367091 cites W2041065272 @default.
- W4313367091 cites W2043352558 @default.
- W4313367091 cites W2044104892 @default.
- W4313367091 cites W2044431799 @default.
- W4313367091 cites W2046997318 @default.
- W4313367091 cites W2049280865 @default.
- W4313367091 cites W2049861445 @default.
- W4313367091 cites W2051096704 @default.
- W4313367091 cites W2051298245 @default.
- W4313367091 cites W2052214918 @default.
- W4313367091 cites W2054556851 @default.
- W4313367091 cites W2056066120 @default.
- W4313367091 cites W2058322328 @default.
- W4313367091 cites W2059874988 @default.
- W4313367091 cites W2062254683 @default.
- W4313367091 cites W2064488943 @default.
- W4313367091 cites W2067389058 @default.
- W4313367091 cites W2067462392 @default.
- W4313367091 cites W2068430855 @default.
- W4313367091 cites W2068825716 @default.
- W4313367091 cites W2069606648 @default.
- W4313367091 cites W2072318662 @default.
- W4313367091 cites W2072897393 @default.
- W4313367091 cites W2073583032 @default.
- W4313367091 cites W2073727854 @default.
- W4313367091 cites W2076228322 @default.
- W4313367091 cites W2076965411 @default.
- W4313367091 cites W2077228161 @default.
- W4313367091 cites W2077334721 @default.
- W4313367091 cites W2078264345 @default.
- W4313367091 cites W2079103525 @default.