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- W4313367373 abstract "Clozapine is an important second-generation antipsychotic that is the gold standard treatment for treatment-resistant schizophrenia. However, clozapine is associated with a number of side effects that can be significant, including agranulocytosis. Therefore, leukocyte and neutrophil counts in patients using clozapine are made periodically with current recommendations. In addition, it has been reported that patients under clozapine therapy may experience elevations in total white blood cell (WBC) and neutrophil counts at times, and these elevations may be persistent. In this case study, we describe a patient who developed chronic leukocytosis after starting clozapine due to persistent schizophrenia symptoms. We aim to explain the approach to the patient's leukocytosis presentation that has been followed for about four years will be explained with a short literature review." @default.
- W4313367373 created "2023-01-06" @default.
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- W4313367373 date "2023-06-01" @default.
- W4313367373 modified "2023-10-14" @default.
- W4313367373 title "An unexpected side effect related to the use of clozapine: Neutrophilic leukocytosis and brief review of the literature" @default.
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- W4313367373 doi "https://doi.org/10.1016/j.psycr.2022.100101" @default.
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