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• W4313367850 endingPage "114446" @default.
• W4313367850 startingPage "114446" @default.
• W4313367850 abstract "Exposure to potentially toxic metal(loid)s (PTMs) in soil may happen via ingestion, inhalation, and dermal pathway. A more accurate risk characterization should consider PTM bioavailability. Using ten soil samples collected in the Montreal area (Canada) near CCA-treated utility poles, this study aims to characterize non-carcinogenic and carcinogenic human health risks associated with As, Cr, Cu, Pb, and Zn through a multi-pathway exposure approach. This innovative study incorporates, for the first time, the bioaccessible fraction of the metal(loid)s for three exposure routes and two different scenarios. For the residential and industrial scenarios, the oral and dermal pathways yielded a hazard index (HI) much higher than 1 with and without bioaccessibility considerations (range 1.7 – 349 without bioaccessibility and 0.8–134 with bioaccessibility), whereas the inhalation pathway caused a lower hazard (HI < 1). For the dermal pathway, the hazard quotient was higher when bioaccessibility of field-collected samples was considered due to inherent assumptions from the US EPA soil approach to calculate the dermal dose. For carcinogenic risk, As and Pb were the most significant contributors to risk for the oral pathway, followed by the same elements for the dermal pathway. The overall carcinogenic risk was higher than the acceptable risk ( > 10−4) with and without bioaccessibility considerations (range 1.9E-4 – 9.6E-3 without bioaccessibility and 6.8E-5 – 3.8E-3 with bioaccessibility). Bioaccessibility tests provide a more accurate assessment of exposure to PTMs compared to total concentrations in soils." @default.
• W4313367850 created "2023-01-06" @default.
• W4313367850 creator A5001770739 @default.
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• W4313367850 date "2023-01-01" @default.
• W4313367850 modified "2023-10-11" @default.
• W4313367850 title "Incorporating oral, inhalation and dermal bioaccessibility into human health risk characterization following exposure to Chromated Copper Arsenate (CCA)-contaminated soils" @default.
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• W4313367850 doi "https://doi.org/10.1016/j.ecoenv.2022.114446" @default.
• W4313367850 hasPublicationYear "2023" @default.
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