FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313371712> ?p ?o ?g. }

• W4313371712 abstract "Background Abnormal blood flow patterns in fetal circulation detected by Doppler ultrasound may indicate poor fetal prognosis. It is also possible that false positive Doppler ultrasound findings could lead to adverse outcomes from unnecessary interventions, including preterm delivery. Objectives The objective of this review was to assess the effects of Doppler ultrasound used to assess fetal well‐being in high‐risk pregnancies on obstetric care and fetal outcomes. Search methods We updated the search of Cochrane Pregnancy and Childbirth's Trials Register on 31 March 2017 and checked reference lists of retrieved studies. Selection criteria Randomised and quasi‐randomised controlled trials of Doppler ultrasound for the investigation of umbilical and fetal vessels waveforms in high‐risk pregnancies compared with no Doppler ultrasound. Cluster‐randomised trials were eligible for inclusion but none were identified. Data collection and analysis Two review authors independently assessed the studies for inclusion, assessed risk of bias and carried out data extraction. Data entry was checked. We assessed the quality of evidence using the GRADE approach. Main results Nineteen trials involving 10,667 women were included. Risk of bias in trials was difficult to assess accurately due to incomplete reporting. None of the evidence relating to our main outcomes was graded as high quality. The quality of evidence was downgraded due to missing information on trial methods, imprecision in risk estimates and heterogeneity. Eighteen of these studies compared the use of Doppler ultrasound of the umbilical artery of the unborn baby with no Doppler or with cardiotocography (CTG). One more recent trial compared Doppler examination of other fetal blood vessels (ductus venosus) with computerised CTG. The use of Doppler ultrasound of the umbilical artery in high‐risk pregnancy was associated with fewer perinatal deaths (risk ratio (RR) 0.71, 95% confidence interval (CI) 0.52 to 0.98, 16 studies, 10,225 babies, 1.2% versus 1.7 %, number needed to treat (NNT) = 203; 95% CI 103 to 4352, evidence graded moderate). The results for stillbirths were consistent with the overall rate of perinatal deaths, although there was no clear difference between groups for this outcome (RR 0.65, 95% CI 0.41 to 1.04; 15 studies, 9560 babies, evidence graded low). Where Doppler ultrasound was used, there were fewer inductions of labour (average RR 0.89, 95% CI 0.80 to 0.99, 10 studies, 5633 women, random‐effects, evidence graded moderate) and fewer caesarean sections (RR 0.90, 95% CI 0.84 to 0.97, 14 studies, 7918 women, evidence graded moderate). There was no comparative long‐term follow‐up of babies exposed to Doppler ultrasound in pregnancy in women at increased risk of complications. No difference was found in operative vaginal births (RR 0.95, 95% CI 0.80 to 1.14, four studies, 2813 women), nor in Apgar scores less than seven at five minutes (RR 0.92, 95% CI 0.69 to 1.24, seven studies, 6321 babies, evidence graded low). Data for serious neonatal morbidity were not pooled due to high heterogeneity between the three studies that reported it (1098 babies) (evidence graded very low). The use of Doppler to evaluate early and late changes in ductus venosus in early fetal growth restriction was not associated with significant differences in any perinatal death after randomisation. However, there was an improvement in long‐term neurological outcome in the cohort of babies in whom the trigger for delivery was either late changes in ductus venosus or abnormalities seen on computerised CTG. Authors' conclusions Current evidence suggests that the use of Doppler ultrasound on the umbilical artery in high‐risk pregnancies reduces the risk of perinatal deaths and may result in fewer obstetric interventions. The results should be interpreted with caution, as the evidence is not of high quality. Serial monitoring of Doppler changes in ductus venosus may be beneficial, but more studies of high quality with follow‐up including neurological development are needed for evidence to be conclusive." @default.
• W4313371712 created "2023-01-06" @default.
• W4313371712 creator A5021408553 @default.
• W4313371712 creator A5056992264 @default.
• W4313371712 creator A5065855316 @default.
• W4313371712 date "2017-06-13" @default.
• W4313371712 modified "2023-10-17" @default.
• W4313371712 title "Fetal and umbilical Doppler ultrasound in high-risk pregnancies" @default.
• W4313371712 cites W12935763 @default.
• W4313371712 cites W1501747113 @default.
• W4313371712 cites W1550707014 @default.
• W4313371712 cites W1601599569 @default.
• W4313371712 cites W1757974377 @default.
• W4313371712 cites W1918360065 @default.
• W4313371712 cites W1967516710 @default.
• W4313371712 cites W1968416900 @default.
• W4313371712 cites W1969519075 @default.
• W4313371712 cites W1971567507 @default.
• W4313371712 cites W1972635550 @default.
• W4313371712 cites W1976985815 @default.
• W4313371712 cites W1977128767 @default.
• W4313371712 cites W1980226836 @default.
• W4313371712 cites W1984425647 @default.
• W4313371712 cites W1985110249 @default.
• W4313371712 cites W1986188027 @default.
• W4313371712 cites W1987772277 @default.
• W4313371712 cites W1991436691 @default.
• W4313371712 cites W1992611378 @default.
• W4313371712 cites W1996299626 @default.
• W4313371712 cites W1999073635 @default.
• W4313371712 cites W2003738618 @default.
• W4313371712 cites W2012730610 @default.
• W4313371712 cites W2029288555 @default.
• W4313371712 cites W2030208157 @default.
• W4313371712 cites W2032999788 @default.
• W4313371712 cites W2035603492 @default.
• W4313371712 cites W2035961915 @default.
• W4313371712 cites W2037458425 @default.
• W4313371712 cites W2039418122 @default.
• W4313371712 cites W2065092234 @default.
• W4313371712 cites W2065703471 @default.
• W4313371712 cites W2067166779 @default.
• W4313371712 cites W2068312357 @default.
• W4313371712 cites W2068344460 @default.
• W4313371712 cites W2069117104 @default.
• W4313371712 cites W2079282203 @default.
• W4313371712 cites W2087621430 @default.
• W4313371712 cites W2093799895 @default.
• W4313371712 cites W2094350085 @default.
• W4313371712 cites W2095530928 @default.
• W4313371712 cites W2110243778 @default.
• W4313371712 cites W2111430949 @default.
• W4313371712 cites W2114971155 @default.
• W4313371712 cites W2115742352 @default.
• W4313371712 cites W2122930409 @default.
• W4313371712 cites W2131113799 @default.
• W4313371712 cites W2134137349 @default.
• W4313371712 cites W2142375372 @default.
• W4313371712 cites W2142422989 @default.
• W4313371712 cites W2142599876 @default.
• W4313371712 cites W2142960568 @default.
• W4313371712 cites W2147771295 @default.
• W4313371712 cites W2156314756 @default.
• W4313371712 cites W2158512558 @default.
• W4313371712 cites W2166103817 @default.
• W4313371712 cites W2170402880 @default.
• W4313371712 cites W2319005641 @default.
• W4313371712 cites W2931515921 @default.
• W4313371712 cites W4230458772 @default.
• W4313371712 cites W4236782188 @default.
• W4313371712 cites W4238840339 @default.
• W4313371712 cites W4239259042 @default.
• W4313371712 cites W4246105701 @default.
• W4313371712 cites W4249456774 @default.
• W4313371712 cites W4297889165 @default.
• W4313371712 doi "https://doi.org/10.1002/14651858.cd007529.pub4" @default.
• W4313371712 hasPublicationYear "2017" @default.
• W4313371712 type Work @default.
• W4313371712 citedByCount "53" @default.
• W4313371712 countsByYear W43133717122017 @default.
• W4313371712 countsByYear W43133717122018 @default.
• W4313371712 countsByYear W43133717122019 @default.
• W4313371712 countsByYear W43133717122020 @default.
• W4313371712 countsByYear W43133717122021 @default.
• W4313371712 countsByYear W43133717122022 @default.
• W4313371712 countsByYear W43133717122023 @default.
• W4313371712 crossrefType "journal-article" @default.
• W4313371712 hasAuthorship W4313371712A5021408553 @default.
• W4313371712 hasAuthorship W4313371712A5056992264 @default.
• W4313371712 hasAuthorship W4313371712A5065855316 @default.
• W4313371712 hasBestOaLocation W43133717122 @default.
• W4313371712 hasConcept C131872663 @default.
• W4313371712 hasConcept C141071460 @default.
• W4313371712 hasConcept C168563851 @default.
• W4313371712 hasConcept C172680121 @default.
• W4313371712 hasConcept C17744445 @default.
• W4313371712 hasConcept C199539241 @default.
• W4313371712 hasConcept C2776046940 @default.
• W4313371712 hasConcept C2776953305 @default.
• W4313371712 hasConcept C2777466982 @default.

• next