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- W4313371773 abstract "The base-catalyzed ring closure ofβ-benzylaspartyl peptides was efficiently suppressed by the addition of phenols (with electron-withdrawing substituents) to the reaction mixtures. From a series of compounds tested, 2,4-dinitrophenol and pentachlorophenol were the most effective. No direct relationship was found between the acidity of the additives and their ability to suppress the formation of aminosuccinyl peptides. The applicability of 2,4-dinitrophenol and pentachlorophenol in practical syntheses was also examined." @default.
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- W4313371773 date "2009-01-12" @default.
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- W4313371773 title "SIDE REACTIONS IN PEPTIDE SYNTHESIS" @default.
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- W4313371773 doi "https://doi.org/10.1111/j.1399-3011.1978.tb02898.x" @default.
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