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- W4313372571 abstract "Abstract The superiority of intracutaneous vaccination against certain infections over the ordinarily used subcutaneous administration of vaccines has been proved repeatedly. This method based on the protective role of the skin although largely neglected in human medicine is known to be successfully used by veterinarians particularly in their fight against anthrax (reviewed by Besredka, 1928) and equine encephalomyelitis (Shoening, Shahan, Osteen and Giltner, 1940). The principle of separate inoculation of virus and immune serum is also advocated in veterinary medicine. Swine are successfully vaccinated against hog-cholera by the virus and immune serum being injected at the same time at different sites and so are cattle against rinderpest. As a whole this method has proven successful although on rare occasions the subcutaneously inoculated immune serum failed to protect the animal. The application of this principle was used in the early immunization of man against yellow fever infection (Sawyer, Kitchen and Lloyd, 1932)." @default.
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- W4313372571 date "1944-01-01" @default.
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- W4313372571 title "Protection against Spotted Fever by Specific Immune Serum Inoculated Intradermally at the Site of Infection" @default.
- W4313372571 doi "https://doi.org/10.4049/jimmunol.48.1.69" @default.
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