Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313373722> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W4313373722 endingPage "83.11" @default.
- W4313373722 startingPage "83.11" @default.
- W4313373722 abstract "Abstract Ulcerative colitis (UC) is a chronic inflammation of the large intestine led by the dysregulation of adaptive and innate immune responses. Recently, specific microbiota has been reported to instruct the immune cells and immune response. We have recently proved the clinical efficacy of “indigo naturalis (IN)”, a Chinese herbal medicine, on patients with UC by the multicenter randomized-controlled trial (INDIGO study, Gastroenterology 2018). 4%IN-fed mice ameliorated DSS-colitis (IN-DSS mice) compared to the normal diet-fed mice (ctrl-DSS mice). The number of IL-22+ ILC3s in the colonic lamina propria in IN-DSS mice increased more than the one in ctrl-DSS mice. We also confirmed that IN-fed diet mice significantly altered gut microbiota composition compared to the normal diet-fed mice. We next inoculated feces obtained from IN-fed mice or normal diet-fed mice to antibiotic treated mice (IN-FMT mice, ctrl-FMT mice respectively). Interestingly, IN-FMT mice significantly restored the pathology of DSS-induced colitis than ctrl-FMT mice with increased number of IL-22+ ILC3s. We showed IN induced specific microbiota which accumulated IL-22+ ILC3s in gut." @default.
- W4313373722 created "2023-01-06" @default.
- W4313373722 creator A5004168351 @default.
- W4313373722 creator A5010646864 @default.
- W4313373722 creator A5011183680 @default.
- W4313373722 creator A5011515466 @default.
- W4313373722 creator A5012085261 @default.
- W4313373722 creator A5018853775 @default.
- W4313373722 creator A5018876928 @default.
- W4313373722 creator A5023463282 @default.
- W4313373722 creator A5033759577 @default.
- W4313373722 creator A5035900623 @default.
- W4313373722 creator A5038943741 @default.
- W4313373722 creator A5052228606 @default.
- W4313373722 creator A5055351518 @default.
- W4313373722 creator A5072961529 @default.
- W4313373722 creator A5087090081 @default.
- W4313373722 date "2020-05-01" @default.
- W4313373722 modified "2023-09-27" @default.
- W4313373722 title "The herbal medicine ‘Indigo naturalis’ altered gut microbiota to accumulate IL-22+ ILC3s" @default.
- W4313373722 doi "https://doi.org/10.4049/jimmunol.204.supp.83.11" @default.
- W4313373722 hasPublicationYear "2020" @default.
- W4313373722 type Work @default.
- W4313373722 citedByCount "0" @default.
- W4313373722 crossrefType "journal-article" @default.
- W4313373722 hasAuthorship W4313373722A5004168351 @default.
- W4313373722 hasAuthorship W4313373722A5010646864 @default.
- W4313373722 hasAuthorship W4313373722A5011183680 @default.
- W4313373722 hasAuthorship W4313373722A5011515466 @default.
- W4313373722 hasAuthorship W4313373722A5012085261 @default.
- W4313373722 hasAuthorship W4313373722A5018853775 @default.
- W4313373722 hasAuthorship W4313373722A5018876928 @default.
- W4313373722 hasAuthorship W4313373722A5023463282 @default.
- W4313373722 hasAuthorship W4313373722A5033759577 @default.
- W4313373722 hasAuthorship W4313373722A5035900623 @default.
- W4313373722 hasAuthorship W4313373722A5038943741 @default.
- W4313373722 hasAuthorship W4313373722A5052228606 @default.
- W4313373722 hasAuthorship W4313373722A5055351518 @default.
- W4313373722 hasAuthorship W4313373722A5072961529 @default.
- W4313373722 hasAuthorship W4313373722A5087090081 @default.
- W4313373722 hasConcept C126322002 @default.
- W4313373722 hasConcept C142316359 @default.
- W4313373722 hasConcept C142362112 @default.
- W4313373722 hasConcept C142724271 @default.
- W4313373722 hasConcept C153349607 @default.
- W4313373722 hasConcept C203014093 @default.
- W4313373722 hasConcept C2775862500 @default.
- W4313373722 hasConcept C2776409635 @default.
- W4313373722 hasConcept C2777310793 @default.
- W4313373722 hasConcept C2777882243 @default.
- W4313373722 hasConcept C2780832600 @default.
- W4313373722 hasConcept C529295009 @default.
- W4313373722 hasConcept C539455810 @default.
- W4313373722 hasConcept C61716771 @default.
- W4313373722 hasConcept C71924100 @default.
- W4313373722 hasConcept C86803240 @default.
- W4313373722 hasConcept C8891405 @default.
- W4313373722 hasConcept C89423630 @default.
- W4313373722 hasConceptScore W4313373722C126322002 @default.
- W4313373722 hasConceptScore W4313373722C142316359 @default.
- W4313373722 hasConceptScore W4313373722C142362112 @default.
- W4313373722 hasConceptScore W4313373722C142724271 @default.
- W4313373722 hasConceptScore W4313373722C153349607 @default.
- W4313373722 hasConceptScore W4313373722C203014093 @default.
- W4313373722 hasConceptScore W4313373722C2775862500 @default.
- W4313373722 hasConceptScore W4313373722C2776409635 @default.
- W4313373722 hasConceptScore W4313373722C2777310793 @default.
- W4313373722 hasConceptScore W4313373722C2777882243 @default.
- W4313373722 hasConceptScore W4313373722C2780832600 @default.
- W4313373722 hasConceptScore W4313373722C529295009 @default.
- W4313373722 hasConceptScore W4313373722C539455810 @default.
- W4313373722 hasConceptScore W4313373722C61716771 @default.
- W4313373722 hasConceptScore W4313373722C71924100 @default.
- W4313373722 hasConceptScore W4313373722C86803240 @default.
- W4313373722 hasConceptScore W4313373722C8891405 @default.
- W4313373722 hasConceptScore W4313373722C89423630 @default.
- W4313373722 hasIssue "1_Supplement" @default.
- W4313373722 hasLocation W43133737221 @default.
- W4313373722 hasOpenAccess W4313373722 @default.
- W4313373722 hasPrimaryLocation W43133737221 @default.
- W4313373722 hasRelatedWork W2001897420 @default.
- W4313373722 hasRelatedWork W2062888014 @default.
- W4313373722 hasRelatedWork W2078879409 @default.
- W4313373722 hasRelatedWork W2152734595 @default.
- W4313373722 hasRelatedWork W2157120511 @default.
- W4313373722 hasRelatedWork W2315612683 @default.
- W4313373722 hasRelatedWork W2895965167 @default.
- W4313373722 hasRelatedWork W2987447925 @default.
- W4313373722 hasRelatedWork W3015279851 @default.
- W4313373722 hasRelatedWork W4313373722 @default.
- W4313373722 hasVolume "204" @default.
- W4313373722 isParatext "false" @default.
- W4313373722 isRetracted "false" @default.
- W4313373722 workType "article" @default.