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- W4313374844 abstract "Drug-induced alopecia can be difficult to diagnose as determining a causative link between the introduction of a drug to the onset of hair loss requires both a detailed patient history as well as a clear understanding of hair growth cycling. Clinical history taking should include a comprehensive time frame dating back at least 3 months. The difficulty in diagnosis lies in detecting the specific offending agent. New case reports and studies are continually being published linking hair loss to a specific drug, however, these studies are routinely correlative in nature without a definitive biological linkage. Despite this, there are well-studied and reported classes of medications with strong evidence of causing alopecia that should be considered when there is high clinical suspicion of drug-induced alopecia. While drug-induced alopecia is often reversible upon cessation of the offending agent, this is often not an acceptable approach for life-saving and long-term use drugs such as chemotherapy agents, anticoagulants, and psychotropics. Furthermore, the emotional and psychological impact of hair loss without intervention poses serious risks to patient well-being and drug regimen compliance. For chemotherapy-induced alopecia, several targeted therapies exist with promising results such as scalp cooling. Topical and oral minoxidil may be used in those experiencing a drug-induced cause of telogen effluvium. More recent therapies focus on the use of growth factors such as VEGF and keratinocyte growth factor. Despite limited evidence-based therapies for the treatment of drug-induced alopecia, a high degree of interest remains in the field for continued investigations into new treatments." @default.
- W4313374844 created "2023-01-06" @default.
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- W4313374844 date "2022-01-01" @default.
- W4313374844 modified "2023-10-16" @default.
- W4313374844 title "28-Year-Old Female with Diffuse Thinning of the Scalp after Isotretinoin and Oral Contraceptives" @default.
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- W4313374844 doi "https://doi.org/10.1007/978-3-031-15820-9_5" @default.
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