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- W4313374905 abstract "Dissecting cellulitis of the scalp (DCS), a lesser known member of the follicular occlusion tetrad, is a rare but morbid condition characterized by draining sinuses and pustules leading to primary cicatricial alopecia. This condition primarily affects young African American men, aged 20–40 years. The cause of DCS is not well understood but it is thought to be partially caused by hyperkeratosis leading to follicular occlusion. The initial presentation of DCS is commonly one or more papules or pustules at the vertex of the scalp. When left untreated, these pustules develop into boggy nodules that form sinus tracts to other lesions. Patients often report flares of symptoms with itching, pain, and foul odor being common complaints. As the disease progresses, patients may notice hair loss at the side of nodules. Microscopy may be helpful in distinguishing DCS from other diseases of the scalp. The histopathology of DCS will vary with stage. In earlier stages, lesions demonstrate dense neutrophilic predominance with associated lymphocytic, histiocytic, and plasmacytic infiltrates. As the inflammation progresses to a more chronic state, lesions contain granulomas consisting of lymphocytes, plasma cells, and foreign-body giant cells. Treatment options also depend on the stage of the disease and range from antibiotics and scalp hygiene, steroids, isotretinoin, immune modulators, and in extreme cases, scalp resection. Patients will require counseling on the psychosocial aspects as well as the relapsing and remitting nature of the disease." @default.
- W4313374905 created "2023-01-06" @default.
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- W4313374905 date "2022-01-01" @default.
- W4313374905 modified "2023-10-16" @default.
- W4313374905 title "44-Year-Old Male with Tender, Draining Lesions and Hair Loss on the Central and Posterior Scalp" @default.
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- W4313374905 doi "https://doi.org/10.1007/978-3-031-15820-9_14" @default.
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