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- W4313376460 abstract "Summary Two types of γ-globulin antigenic determinants (I and II) are described. These determinants are common to all γ-globulin groups. The 6.6 S γ-globulins, γ1-macroglobulins, and β2A-globulins of normal serum, and the γ-microglobulins of normal urine were divided into two types by the presence of type I or II antigenic determinants. Individual γ-globulin molecules appear to have either type I or II, but not both, types of antigenic determinants. All individual sera tested had both type I and II γ-globulin molecules. In normal serum the type I γ-globulins predominate in a ratio of about 2:1. Similar ratios were observed in normal serum 6.6 S γ-globulins and γ1-macroglobulins, but more nearly equal ratios of type I and II molecules were found in the γ-microglobulins of normal urine. Type I and II γ-globulin molecules are similarly distributed throghout the entire range of electrophoretic mobility of normal γ-globulin. Type I and II γ-globulin molecules also are similar in ultracentrifugal and chromatographic behavior and in hexose content. Preliminary observations, however, indicate that the InV genetic factors are more likely to be on type I than on type II molecules." @default.
- W4313376460 created "2023-01-06" @default.
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- W4313376460 date "1963-10-01" @default.
- W4313376460 modified "2023-10-16" @default.
- W4313376460 title "Two Types of 6.6 S γ-Globulins, β2A-Globulins and 18 S γ1-Macroglobulins in Normal Serum and γ-Microglobulins in Normal Urine" @default.
- W4313376460 doi "https://doi.org/10.4049/jimmunol.91.4.438" @default.
- W4313376460 hasPublicationYear "1963" @default.
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