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- W4313376464 abstract "Summary The x-ray sensitivity of normal histocompatibility antigens in mice was studied. Strong antigens associated with the H-2 locus were found to be resistant to as much as 12,800 r in vitro, in that mice inoculated with such heavily irradiated cells were immunized by them and gave second set responses to subsequent skin grafts. Weak antigens associated with H-1 and H-3 loci were effectively destroyed by as little as 400 r, failing to induce immunity after irradiation in vitro. The cells used to induce immunity were spleen cells and a methylcholanthrene-induced sarcoma. Possible biologic relationships between strong and weak transplantation antigens are discussed and a reason for their different sensitivities to irradiation suggested." @default.
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- W4313376464 date "1964-05-01" @default.
- W4313376464 modified "2023-10-04" @default.
- W4313376464 title "The Effect of X-Ray on the Antigenicity of Donor Cells in Transplantation Immunity" @default.
- W4313376464 doi "https://doi.org/10.4049/jimmunol.92.5.811" @default.
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