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- W4313376485 abstract "Summary In Macaca mulatta, infection with the Trinidad strain of VEE virus produced a benign, febrile illness with no clinical evidence of CNS involvement. Histologic alterations in the brains of these animals were limited to lymphocytic perivascular cuffing and to focal infiltration with glial cells. Morphologic evidence of neuronal injury was rare and, when seen, was limited to cells within the glial nodules. Both of these inflammatory responses were markedly suppressed by the administration of cortisone acctate, but only when the drug was given for the first time during the period of secondary fever. When cortisone was begun prior to inoculation and continued during the febrile period suppression of the inflammatory responses did not occur. In neither instance was drug administration found to modify the clinical disease nor to modify materially the eventual antibody response." @default.
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- W4313376485 date "1961-11-01" @default.
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- W4313376485 title "Studies on the Virus of Venezuelan Equine Encephalomyelitis" @default.
- W4313376485 doi "https://doi.org/10.4049/jimmunol.87.5.504" @default.
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