FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313379631> ?p ?o ?g. }

• W4313379631 endingPage "203" @default.
• W4313379631 startingPage "193" @default.
• W4313379631 abstract "Introduction Acute kidney injury (AKI) indicates an impairment of the renal function following blunt trauma. It is multifactorial and associated with an increased risk of morbidity and mortality. The incidence and risk factors of AKI in young patients with trauma are not well-described. This study aimed to evaluate the incidence, clinical characteristics, and outcomes of post-traumatic AKI. We hypothesized that AKI is associated with worse outcomes in patients with trauma. Methods This was a retrospective study of all adult trauma patients admitted to a level 1 trauma center between 2011 and 2021. AKI was diagnosed on the basis of the Kidney Disease Improving Global Outcomes criteria. Data were collected and analyzed for patients with and without AKI using chi-square test and Student's t-test. Multivariate logistic regression analysis and Kaplan–Meier curves were performed. Results A total of 17,341 patients with trauma were evaluated, of which 140 (0.8%) developed AKI. Patients with AKI were older (40 ± 20 versus 32 ± 16 y), had more comorbidities, and had a higher injury severity score (ISS) and in-hospital mortality (65% versus 3.2%) than non-AKI patients. Direct trauma to the kidney was reported in only nine (6.4%) patients in the AKI group. Among patients with AKI, nonsurvivors had a higher ISS and were more likely to have hypotension, elevated serum lactate, positive troponin, and a lower platelet-to-lymphocyte ratio than survivors. Multiple logistic regression analyses showed that age, ISS, acute respiratory distress syndrome, blood transfusion, diabetes mellitus, onadmission Glasgow coma scale score, and shock index were predictors of AKI in trauma patients, whereas ISS (odds ratio (OR) = 1.05; 95% confidence interval (CI):1.003-1.100; P = 0.03), serum lactate level (OR = 1.25; 95% CI: 1.019-1.533; P = 0.03), and hypotension (OR = 3.22; 95% CI: 1.044-9.945; P = 0.04) were independent predictors of mortality in patients with posttraumatic AKI. Kaplan–Meier survival analysis showed significant differences in mortality among the three stages of AKI (P = 0.03), with the worst outcome in stage III. However, after adjusting for age, hypotension, and ISS, the Cox regression model showed that only stage I had better survival than stages II and III, whereas no survival difference was noted between stages II and III (P = 0.06). Conclusions AKI in young trauma patients is uncommon and associated with a prolonged hospital course and higher mortality. This study identified factors that independently predicted the development of AKI and its outcomes in patients with trauma. However, further prospective and multicenter studies are required to minimize the incidence and complications of posttraumatic AKI." @default.
• W4313379631 created "2023-01-06" @default.
• W4313379631 creator A5005006623 @default.
• W4313379631 creator A5032924875 @default.
• W4313379631 creator A5049784855 @default.
• W4313379631 creator A5088761895 @default.
• W4313379631 date "2023-04-01" @default.
• W4313379631 modified "2023-10-16" @default.
• W4313379631 title "Predisposing Factors and Outcome of Acute Kidney Injury After Blunt Trauma: A 10-Year Study" @default.
• W4313379631 cites W1206073163 @default.
• W4313379631 cites W1971170530 @default.
• W4313379631 cites W1983640477 @default.
• W4313379631 cites W2024297271 @default.
• W4313379631 cites W2028631019 @default.
• W4313379631 cites W2030743629 @default.
• W4313379631 cites W2038510079 @default.
• W4313379631 cites W2058823684 @default.
• W4313379631 cites W2060902714 @default.
• W4313379631 cites W2107765069 @default.
• W4313379631 cites W2137003201 @default.
• W4313379631 cites W2163464935 @default.
• W4313379631 cites W2168417068 @default.
• W4313379631 cites W2183748269 @default.
• W4313379631 cites W2554024078 @default.
• W4313379631 cites W2621058175 @default.
• W4313379631 cites W2746264294 @default.
• W4313379631 cites W2904274156 @default.
• W4313379631 cites W2911456654 @default.
• W4313379631 cites W2912108453 @default.
• W4313379631 cites W2914205477 @default.
• W4313379631 cites W2973027510 @default.
• W4313379631 cites W2991059191 @default.
• W4313379631 cites W3015979116 @default.
• W4313379631 cites W3036442948 @default.
• W4313379631 cites W3106993662 @default.
• W4313379631 cites W3111522632 @default.
• W4313379631 cites W3130823150 @default.
• W4313379631 cites W3136977141 @default.
• W4313379631 cites W3177086065 @default.
• W4313379631 doi "https://doi.org/10.1016/j.jss.2022.12.001" @default.
• W4313379631 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36586312" @default.
• W4313379631 hasPublicationYear "2023" @default.
• W4313379631 type Work @default.
• W4313379631 citedByCount "0" @default.
• W4313379631 crossrefType "journal-article" @default.
• W4313379631 hasAuthorship W4313379631A5005006623 @default.
• W4313379631 hasAuthorship W4313379631A5032924875 @default.
• W4313379631 hasAuthorship W4313379631A5049784855 @default.
• W4313379631 hasAuthorship W4313379631A5088761895 @default.
• W4313379631 hasConcept C120665830 @default.
• W4313379631 hasConcept C121332964 @default.
• W4313379631 hasConcept C126322002 @default.
• W4313379631 hasConcept C141071460 @default.
• W4313379631 hasConcept C151956035 @default.
• W4313379631 hasConcept C159641895 @default.
• W4313379631 hasConcept C167135981 @default.
• W4313379631 hasConcept C17624336 @default.
• W4313379631 hasConcept C190385971 @default.
• W4313379631 hasConcept C194828623 @default.
• W4313379631 hasConcept C2777521253 @default.
• W4313379631 hasConcept C2780110798 @default.
• W4313379631 hasConcept C2780472472 @default.
• W4313379631 hasConcept C3017944768 @default.
• W4313379631 hasConcept C61511704 @default.
• W4313379631 hasConcept C71924100 @default.
• W4313379631 hasConcept C85004164 @default.
• W4313379631 hasConceptScore W4313379631C120665830 @default.
• W4313379631 hasConceptScore W4313379631C121332964 @default.
• W4313379631 hasConceptScore W4313379631C126322002 @default.
• W4313379631 hasConceptScore W4313379631C141071460 @default.
• W4313379631 hasConceptScore W4313379631C151956035 @default.
• W4313379631 hasConceptScore W4313379631C159641895 @default.
• W4313379631 hasConceptScore W4313379631C167135981 @default.
• W4313379631 hasConceptScore W4313379631C17624336 @default.
• W4313379631 hasConceptScore W4313379631C190385971 @default.
• W4313379631 hasConceptScore W4313379631C194828623 @default.
• W4313379631 hasConceptScore W4313379631C2777521253 @default.
• W4313379631 hasConceptScore W4313379631C2780110798 @default.
• W4313379631 hasConceptScore W4313379631C2780472472 @default.
• W4313379631 hasConceptScore W4313379631C3017944768 @default.
• W4313379631 hasConceptScore W4313379631C61511704 @default.
• W4313379631 hasConceptScore W4313379631C71924100 @default.
• W4313379631 hasConceptScore W4313379631C85004164 @default.
• W4313379631 hasLocation W43133796311 @default.
• W4313379631 hasLocation W43133796312 @default.
• W4313379631 hasOpenAccess W4313379631 @default.
• W4313379631 hasPrimaryLocation W43133796311 @default.
• W4313379631 hasRelatedWork W2004351652 @default.
• W4313379631 hasRelatedWork W2087025818 @default.
• W4313379631 hasRelatedWork W2111212343 @default.
• W4313379631 hasRelatedWork W2164169917 @default.
• W4313379631 hasRelatedWork W2432723366 @default.
• W4313379631 hasRelatedWork W2525258897 @default.
• W4313379631 hasRelatedWork W2984647402 @default.
• W4313379631 hasRelatedWork W3178765273 @default.
• W4313379631 hasRelatedWork W4282933268 @default.
• W4313379631 hasRelatedWork W4313379631 @default.
• W4313379631 hasVolume "284" @default.

• next