Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313379904> ?p ?o ?g. }
- W4313379904 endingPage "110540" @default.
- W4313379904 startingPage "110540" @default.
- W4313379904 abstract "Non-coding RNAs (ncRNAs) induced competing endogenous RNAs (ceRNA) play crucial roles in various biological process by regulating target gene expression. However, the studies of ceRNA networks in the regulation of ovarian ovulation processing of chicken remains deficient compared to that in mammals. Our present study revealed that circEML1 was differential expressed in hen's ovarian tissues at different ages (15 W/20 W/30 W/68 W) and identified as a loop structure from EML1 pre-mRNA, which promoted the expressions of CYP19A1/StAR and E2/P4 secretion in follicular granulosa cells (GCs). Furthermore, circEML1 could serve as a sponge of gga-miR-449a and also found that IGF2BP3 was targeted by gga-miR-449a to co-participate in the steroidogenesis, which possibly act the regulatory role via mTOR/p38MAPK pathways. Meanwhile, in the rescue experiment, gga-miR-449a could reverse the promoting role of circEML1 to IGF2BP3 and steroidogenesis. Eventually, this study suggested that circEML1/gga-miR-449a/IGF2BP3 axis exerted an important role in the steroidogenesis in GCs of chicken." @default.
- W4313379904 created "2023-01-06" @default.
- W4313379904 creator A5007728943 @default.
- W4313379904 creator A5010000529 @default.
- W4313379904 creator A5012677271 @default.
- W4313379904 creator A5012917583 @default.
- W4313379904 creator A5017097972 @default.
- W4313379904 creator A5031695776 @default.
- W4313379904 creator A5054871862 @default.
- W4313379904 creator A5057067538 @default.
- W4313379904 creator A5058913315 @default.
- W4313379904 creator A5066290990 @default.
- W4313379904 creator A5066432875 @default.
- W4313379904 creator A5086458410 @default.
- W4313379904 creator A5087312259 @default.
- W4313379904 date "2023-01-01" @default.
- W4313379904 modified "2023-10-05" @default.
- W4313379904 title "CircEML1 facilitates the steroid synthesis in follicular granulosa cells of chicken through sponging gga-miR-449a to release IGF2BP3 expression" @default.
- W4313379904 cites W1488155694 @default.
- W4313379904 cites W1986475509 @default.
- W4313379904 cites W2014162007 @default.
- W4313379904 cites W2025098484 @default.
- W4313379904 cites W2038774738 @default.
- W4313379904 cites W2059073003 @default.
- W4313379904 cites W2061224512 @default.
- W4313379904 cites W2064165694 @default.
- W4313379904 cites W2070497118 @default.
- W4313379904 cites W2070777085 @default.
- W4313379904 cites W2078442918 @default.
- W4313379904 cites W2101681543 @default.
- W4313379904 cites W2117720293 @default.
- W4313379904 cites W2120509278 @default.
- W4313379904 cites W2138237282 @default.
- W4313379904 cites W2157457685 @default.
- W4313379904 cites W2160322468 @default.
- W4313379904 cites W2164938105 @default.
- W4313379904 cites W2168075403 @default.
- W4313379904 cites W2173456767 @default.
- W4313379904 cites W2265936417 @default.
- W4313379904 cites W2302185643 @default.
- W4313379904 cites W2557141539 @default.
- W4313379904 cites W2587414698 @default.
- W4313379904 cites W2626006855 @default.
- W4313379904 cites W2752542339 @default.
- W4313379904 cites W2767385021 @default.
- W4313379904 cites W2768096340 @default.
- W4313379904 cites W2793785833 @default.
- W4313379904 cites W2797818920 @default.
- W4313379904 cites W2897895078 @default.
- W4313379904 cites W2908682015 @default.
- W4313379904 cites W2912444667 @default.
- W4313379904 cites W2921227142 @default.
- W4313379904 cites W2929669441 @default.
- W4313379904 cites W2944031662 @default.
- W4313379904 cites W2964331590 @default.
- W4313379904 cites W2964746712 @default.
- W4313379904 cites W2985685822 @default.
- W4313379904 cites W2990125632 @default.
- W4313379904 cites W2999013831 @default.
- W4313379904 cites W3009218638 @default.
- W4313379904 cites W3009607405 @default.
- W4313379904 cites W3022988413 @default.
- W4313379904 cites W3041901244 @default.
- W4313379904 cites W3043059397 @default.
- W4313379904 cites W3043361538 @default.
- W4313379904 cites W3098781082 @default.
- W4313379904 cites W3117694852 @default.
- W4313379904 cites W3134952660 @default.
- W4313379904 cites W3136827098 @default.
- W4313379904 cites W3156108593 @default.
- W4313379904 cites W3169159462 @default.
- W4313379904 cites W3184037783 @default.
- W4313379904 cites W3184203963 @default.
- W4313379904 cites W3207132839 @default.
- W4313379904 cites W3216292832 @default.
- W4313379904 cites W4200038820 @default.
- W4313379904 cites W4210243756 @default.
- W4313379904 doi "https://doi.org/10.1016/j.ygeno.2022.110540" @default.
- W4313379904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36563917" @default.
- W4313379904 hasPublicationYear "2023" @default.
- W4313379904 type Work @default.
- W4313379904 citedByCount "0" @default.
- W4313379904 crossrefType "journal-article" @default.
- W4313379904 hasAuthorship W4313379904A5007728943 @default.
- W4313379904 hasAuthorship W4313379904A5010000529 @default.
- W4313379904 hasAuthorship W4313379904A5012677271 @default.
- W4313379904 hasAuthorship W4313379904A5012917583 @default.
- W4313379904 hasAuthorship W4313379904A5017097972 @default.
- W4313379904 hasAuthorship W4313379904A5031695776 @default.
- W4313379904 hasAuthorship W4313379904A5054871862 @default.
- W4313379904 hasAuthorship W4313379904A5057067538 @default.
- W4313379904 hasAuthorship W4313379904A5058913315 @default.
- W4313379904 hasAuthorship W4313379904A5066290990 @default.
- W4313379904 hasAuthorship W4313379904A5066432875 @default.
- W4313379904 hasAuthorship W4313379904A5086458410 @default.
- W4313379904 hasAuthorship W4313379904A5087312259 @default.
- W4313379904 hasBestOaLocation W43133799041 @default.
- W4313379904 hasConcept C104317684 @default.