Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313379963> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W4313379963 endingPage "100888" @default.
- W4313379963 startingPage "100888" @default.
- W4313379963 abstract "The Hepamet fibrosis score was introduced for the diagnosis of advanced liver fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). To date, external validation is limited, and its utility in combination with liver stiffness measurement (LSM) has not been explored.This is a cross-sectional study on NAFLD patients who had a liver biopsy and LSM on the same day. The diagnostic performance of the Hepamet fibrosis score was evaluated using the area under the receiver operating characteristic curve (AUROC).The data for 196 patients were analyzed (mean age 50 ± 11 years old, 50% men, 56.6% Malay, 27.6% Chinese, 15.8% Indian, 67.9% NASH, 15.8% advanced liver fibrosis). The AUROC of Hepamet fibrosis score for the diagnosis of advanced liver fibrosis was 0.85 (95% CI, 0.80 - 0.91). Using the <0.12 and ≥0.47 cut-offs from the original study, the sensitivity, specificity, positive predictive value, negative predictive value, the proportion of indeterminate results and misclassification rate were 81.8%, 91.8%, 47.4%, 98.2%, 32.1% and 6.1%, respectively. Using LSM <10 kPa and ≥15 kPa for the diagnosis of absence and presence of advanced liver fibrosis, respectively, in patients with Hepamet fibrosis score ≥0.47 (i.e., the two-step approach) reduced indeterminate results and misclassification to 16.1% and 3.6%, respectively.We found the Hepamet fibrosis score to have good diagnostic accuracy in a population that was largely unrepresented in earlier work and demonstrated its utility in a two-step approach with LSM for the diagnosis of advanced liver fibrosis." @default.
- W4313379963 created "2023-01-06" @default.
- W4313379963 creator A5006264720 @default.
- W4313379963 creator A5009827814 @default.
- W4313379963 creator A5032141849 @default.
- W4313379963 creator A5036271449 @default.
- W4313379963 creator A5046267888 @default.
- W4313379963 creator A5066927571 @default.
- W4313379963 creator A5086873345 @default.
- W4313379963 date "2023-03-01" @default.
- W4313379963 modified "2023-09-26" @default.
- W4313379963 title "Validation of the Hepamet fibrosis score in a multi-ethnic Asian population" @default.
- W4313379963 cites W1761288624 @default.
- W4313379963 cites W2032846344 @default.
- W4313379963 cites W2067740038 @default.
- W4313379963 cites W2081324449 @default.
- W4313379963 cites W2092555657 @default.
- W4313379963 cites W2093904708 @default.
- W4313379963 cites W2107732097 @default.
- W4313379963 cites W2112496618 @default.
- W4313379963 cites W2156792510 @default.
- W4313379963 cites W2204688218 @default.
- W4313379963 cites W2580009538 @default.
- W4313379963 cites W2607263910 @default.
- W4313379963 cites W2734724639 @default.
- W4313379963 cites W2919371842 @default.
- W4313379963 cites W2920805195 @default.
- W4313379963 cites W2952054942 @default.
- W4313379963 cites W3038092240 @default.
- W4313379963 cites W3095590613 @default.
- W4313379963 cites W3119030109 @default.
- W4313379963 cites W4220974088 @default.
- W4313379963 cites W4238714725 @default.
- W4313379963 cites W4239096779 @default.
- W4313379963 doi "https://doi.org/10.1016/j.aohep.2022.100888" @default.
- W4313379963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36586588" @default.
- W4313379963 hasPublicationYear "2023" @default.
- W4313379963 type Work @default.
- W4313379963 citedByCount "2" @default.
- W4313379963 countsByYear W43133799632023 @default.
- W4313379963 crossrefType "journal-article" @default.
- W4313379963 hasAuthorship W4313379963A5006264720 @default.
- W4313379963 hasAuthorship W4313379963A5009827814 @default.
- W4313379963 hasAuthorship W4313379963A5032141849 @default.
- W4313379963 hasAuthorship W4313379963A5036271449 @default.
- W4313379963 hasAuthorship W4313379963A5046267888 @default.
- W4313379963 hasAuthorship W4313379963A5066927571 @default.
- W4313379963 hasAuthorship W4313379963A5086873345 @default.
- W4313379963 hasBestOaLocation W43133799631 @default.
- W4313379963 hasConcept C126322002 @default.
- W4313379963 hasConcept C198433322 @default.
- W4313379963 hasConcept C2775934546 @default.
- W4313379963 hasConcept C2777766500 @default.
- W4313379963 hasConcept C2778772119 @default.
- W4313379963 hasConcept C2779134260 @default.
- W4313379963 hasConcept C2780559512 @default.
- W4313379963 hasConcept C2908647359 @default.
- W4313379963 hasConcept C2994217296 @default.
- W4313379963 hasConcept C58471807 @default.
- W4313379963 hasConcept C71924100 @default.
- W4313379963 hasConcept C90924648 @default.
- W4313379963 hasConcept C99454951 @default.
- W4313379963 hasConceptScore W4313379963C126322002 @default.
- W4313379963 hasConceptScore W4313379963C198433322 @default.
- W4313379963 hasConceptScore W4313379963C2775934546 @default.
- W4313379963 hasConceptScore W4313379963C2777766500 @default.
- W4313379963 hasConceptScore W4313379963C2778772119 @default.
- W4313379963 hasConceptScore W4313379963C2779134260 @default.
- W4313379963 hasConceptScore W4313379963C2780559512 @default.
- W4313379963 hasConceptScore W4313379963C2908647359 @default.
- W4313379963 hasConceptScore W4313379963C2994217296 @default.
- W4313379963 hasConceptScore W4313379963C58471807 @default.
- W4313379963 hasConceptScore W4313379963C71924100 @default.
- W4313379963 hasConceptScore W4313379963C90924648 @default.
- W4313379963 hasConceptScore W4313379963C99454951 @default.
- W4313379963 hasIssue "2" @default.
- W4313379963 hasLocation W43133799631 @default.
- W4313379963 hasLocation W43133799632 @default.
- W4313379963 hasOpenAccess W4313379963 @default.
- W4313379963 hasPrimaryLocation W43133799631 @default.
- W4313379963 hasRelatedWork W2130612870 @default.
- W4313379963 hasRelatedWork W2231121666 @default.
- W4313379963 hasRelatedWork W2391586629 @default.
- W4313379963 hasRelatedWork W2393714804 @default.
- W4313379963 hasRelatedWork W2468063907 @default.
- W4313379963 hasRelatedWork W2760913729 @default.
- W4313379963 hasRelatedWork W3198552182 @default.
- W4313379963 hasRelatedWork W4313379963 @default.
- W4313379963 hasRelatedWork W4318026411 @default.
- W4313379963 hasRelatedWork W4378516070 @default.
- W4313379963 hasVolume "28" @default.
- W4313379963 isParatext "false" @default.
- W4313379963 isRetracted "false" @default.
- W4313379963 workType "article" @default.