Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313385384> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W4313385384 endingPage "116.8" @default.
- W4313385384 startingPage "116.8" @default.
- W4313385384 abstract "Abstract Batf3-dependent classical dendritic cells (cDCs) are essential for cross-presentation and clearance of intracellular pathogens through priming of CD8 T cells. By analyzing differences in gene expression between cDC subsets we identified vesicular transport molecules unique to cross-presenting dendritic cell subsets. RAB43, a GTPase that is localized to the golgi, is selectively expressed in Batf3-dependent CD8a+ and CD103+ cDCs and was highly conserved between mouse and human. Mice with germline and conditional Rab43 deletions are viable and fertile with normal hematopoiesis. However, mice lacking Rab43 showed reduced cross-presentation of cell-associated, but not soluble, antigens both in vitro and in vivo. Bone-marrow derived DCs (BMDCs) from Rab43 deficient mice show normal cross-presentation efficiency, suggesting that Rab43 is involved in optimizing cross-presentation in vivo through a pathway unique to CD8a+ DCs." @default.
- W4313385384 created "2023-01-06" @default.
- W4313385384 creator A5001701877 @default.
- W4313385384 creator A5019042569 @default.
- W4313385384 creator A5019696169 @default.
- W4313385384 creator A5036089606 @default.
- W4313385384 creator A5040420168 @default.
- W4313385384 creator A5050091823 @default.
- W4313385384 creator A5060155679 @default.
- W4313385384 creator A5085864834 @default.
- W4313385384 creator A5086115826 @default.
- W4313385384 creator A5090464003 @default.
- W4313385384 creator A5091604243 @default.
- W4313385384 date "2016-05-01" @default.
- W4313385384 modified "2023-09-23" @default.
- W4313385384 title "Rab43 facilitates cross-presentation of cell-associated antigens by CD8a+ dendritic cells" @default.
- W4313385384 doi "https://doi.org/10.4049/jimmunol.196.supp.116.8" @default.
- W4313385384 hasPublicationYear "2016" @default.
- W4313385384 type Work @default.
- W4313385384 citedByCount "0" @default.
- W4313385384 crossrefType "journal-article" @default.
- W4313385384 hasAuthorship W4313385384A5001701877 @default.
- W4313385384 hasAuthorship W4313385384A5019042569 @default.
- W4313385384 hasAuthorship W4313385384A5019696169 @default.
- W4313385384 hasAuthorship W4313385384A5036089606 @default.
- W4313385384 hasAuthorship W4313385384A5040420168 @default.
- W4313385384 hasAuthorship W4313385384A5050091823 @default.
- W4313385384 hasAuthorship W4313385384A5060155679 @default.
- W4313385384 hasAuthorship W4313385384A5085864834 @default.
- W4313385384 hasAuthorship W4313385384A5086115826 @default.
- W4313385384 hasAuthorship W4313385384A5090464003 @default.
- W4313385384 hasAuthorship W4313385384A5091604243 @default.
- W4313385384 hasConcept C100701293 @default.
- W4313385384 hasConcept C104317684 @default.
- W4313385384 hasConcept C109159458 @default.
- W4313385384 hasConcept C127716648 @default.
- W4313385384 hasConcept C147483822 @default.
- W4313385384 hasConcept C167672396 @default.
- W4313385384 hasConcept C202751555 @default.
- W4313385384 hasConcept C203014093 @default.
- W4313385384 hasConcept C207001950 @default.
- W4313385384 hasConcept C2776051438 @default.
- W4313385384 hasConcept C2776090121 @default.
- W4313385384 hasConcept C2778170410 @default.
- W4313385384 hasConcept C2778973524 @default.
- W4313385384 hasConcept C2779919695 @default.
- W4313385384 hasConcept C28328180 @default.
- W4313385384 hasConcept C54355233 @default.
- W4313385384 hasConcept C59822182 @default.
- W4313385384 hasConcept C81444415 @default.
- W4313385384 hasConcept C83464605 @default.
- W4313385384 hasConcept C86803240 @default.
- W4313385384 hasConcept C8891405 @default.
- W4313385384 hasConcept C95444343 @default.
- W4313385384 hasConceptScore W4313385384C100701293 @default.
- W4313385384 hasConceptScore W4313385384C104317684 @default.
- W4313385384 hasConceptScore W4313385384C109159458 @default.
- W4313385384 hasConceptScore W4313385384C127716648 @default.
- W4313385384 hasConceptScore W4313385384C147483822 @default.
- W4313385384 hasConceptScore W4313385384C167672396 @default.
- W4313385384 hasConceptScore W4313385384C202751555 @default.
- W4313385384 hasConceptScore W4313385384C203014093 @default.
- W4313385384 hasConceptScore W4313385384C207001950 @default.
- W4313385384 hasConceptScore W4313385384C2776051438 @default.
- W4313385384 hasConceptScore W4313385384C2776090121 @default.
- W4313385384 hasConceptScore W4313385384C2778170410 @default.
- W4313385384 hasConceptScore W4313385384C2778973524 @default.
- W4313385384 hasConceptScore W4313385384C2779919695 @default.
- W4313385384 hasConceptScore W4313385384C28328180 @default.
- W4313385384 hasConceptScore W4313385384C54355233 @default.
- W4313385384 hasConceptScore W4313385384C59822182 @default.
- W4313385384 hasConceptScore W4313385384C81444415 @default.
- W4313385384 hasConceptScore W4313385384C83464605 @default.
- W4313385384 hasConceptScore W4313385384C86803240 @default.
- W4313385384 hasConceptScore W4313385384C8891405 @default.
- W4313385384 hasConceptScore W4313385384C95444343 @default.
- W4313385384 hasIssue "1_Supplement" @default.
- W4313385384 hasLocation W43133853841 @default.
- W4313385384 hasOpenAccess W4313385384 @default.
- W4313385384 hasPrimaryLocation W43133853841 @default.
- W4313385384 hasRelatedWork W1981274926 @default.
- W4313385384 hasRelatedWork W2023179869 @default.
- W4313385384 hasRelatedWork W2072709441 @default.
- W4313385384 hasRelatedWork W2149365463 @default.
- W4313385384 hasRelatedWork W2154919512 @default.
- W4313385384 hasRelatedWork W2159294823 @default.
- W4313385384 hasRelatedWork W2319811460 @default.
- W4313385384 hasRelatedWork W2801179043 @default.
- W4313385384 hasRelatedWork W4281479110 @default.
- W4313385384 hasRelatedWork W4313385384 @default.
- W4313385384 hasVolume "196" @default.
- W4313385384 isParatext "false" @default.
- W4313385384 isRetracted "false" @default.
- W4313385384 workType "article" @default.