FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313389046> ?p ?o ?g. }

• W4313389046 endingPage "217" @default.
• W4313389046 startingPage "217" @default.
• W4313389046 abstract "Intra-Uterine Growth Restriction (IUGR) is a risk factor for many adult-onset chronic diseases, such as diabetes and obesity. These diseases are associated with intestinal microbiome perturbations (dysbiosis). The establishment of an intestinal microbiome begins in utero and continues postnatally (PN). Hypercaloric diet-induced dysbiosis is a major driver of childhood obesity. We hypothesized that different postnatal diets superimposed on IUGR will alter the postnatal intestinal microbiome. We compared four experimental rat groups: (1) Ad lib fed regular chow diet pre- and postnatally (CON), (2–3) IUGR induced by maternal caloric restriction prenatally followed postnatally (PN) by either (2) the control diet (IUGR-RC) or (3) High-Fat-high-fructose (IUGR-HFhf) diet, and lastly (4) HFhf ad lib pre- and postnatally (HFhf). Fecal samples were collected from dams and male and female rat offspring at postnatal day 2, 21, and adult day 180 for 16S rRNA gene sequencing. Maternal diet induced IUGR led to dysbiosis of the intestinal microbiome at PN21. Postnatal HFhf diet significantly reduced microbial diversity and worsened dysbiosis reflected by an increased Gammaproteobacteria/Clostridia ratio. Dysbiosis arising from a mismatch between IUGR and a postnatal HFhf diet may contribute to increased risk of the IUGR offspring for subsequent detrimental health problems." @default.
• W4313389046 created "2023-01-06" @default.
• W4313389046 creator A5019669914 @default.
• W4313389046 creator A5033603757 @default.
• W4313389046 creator A5037019367 @default.
• W4313389046 creator A5060244044 @default.
• W4313389046 creator A5078752558 @default.
• W4313389046 creator A5080354069 @default.
• W4313389046 creator A5081342993 @default.
• W4313389046 date "2023-01-01" @default.
• W4313389046 modified "2023-10-14" @default.
• W4313389046 title "Variation in the Early Life and Adult Intestinal Microbiome of Intra-Uterine Growth Restricted Rat Offspring Exposed to a High Fat and Fructose Diet" @default.
• W4313389046 cites W1579591484 @default.
• W4313389046 cites W1901435509 @default.
• W4313389046 cites W1966552488 @default.
• W4313389046 cites W1990651360 @default.
• W4313389046 cites W1996175687 @default.
• W4313389046 cites W2020541351 @default.
• W4313389046 cites W2032230795 @default.
• W4313389046 cites W2056279562 @default.
• W4313389046 cites W2067700911 @default.
• W4313389046 cites W2070296690 @default.
• W4313389046 cites W2073332363 @default.
• W4313389046 cites W2080283023 @default.
• W4313389046 cites W2081313422 @default.
• W4313389046 cites W2085842186 @default.
• W4313389046 cites W2104890139 @default.
• W4313389046 cites W2136500114 @default.
• W4313389046 cites W2142536690 @default.
• W4313389046 cites W2146969370 @default.
• W4313389046 cites W2164282432 @default.
• W4313389046 cites W2167062509 @default.
• W4313389046 cites W2228687373 @default.
• W4313389046 cites W2238436970 @default.
• W4313389046 cites W2286082361 @default.
• W4313389046 cites W2401404581 @default.
• W4313389046 cites W2426140394 @default.
• W4313389046 cites W2489396395 @default.
• W4313389046 cites W2516927384 @default.
• W4313389046 cites W2532214571 @default.
• W4313389046 cites W2606717595 @default.
• W4313389046 cites W2733471197 @default.
• W4313389046 cites W2801440610 @default.
• W4313389046 cites W2914542841 @default.
• W4313389046 cites W2923114414 @default.
• W4313389046 cites W2959992540 @default.
• W4313389046 cites W2963276645 @default.
• W4313389046 cites W2967239885 @default.
• W4313389046 cites W2971527784 @default.
• W4313389046 cites W2976587368 @default.
• W4313389046 cites W2985646021 @default.
• W4313389046 cites W3027118763 @default.
• W4313389046 cites W3043062835 @default.
• W4313389046 cites W3159685258 @default.
• W4313389046 cites W4200022150 @default.
• W4313389046 doi "https://doi.org/10.3390/nu15010217" @default.
• W4313389046 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36615874" @default.
• W4313389046 hasPublicationYear "2023" @default.
• W4313389046 type Work @default.
• W4313389046 citedByCount "0" @default.
• W4313389046 crossrefType "journal-article" @default.
• W4313389046 hasAuthorship W4313389046A5019669914 @default.
• W4313389046 hasAuthorship W4313389046A5033603757 @default.
• W4313389046 hasAuthorship W4313389046A5037019367 @default.
• W4313389046 hasAuthorship W4313389046A5060244044 @default.
• W4313389046 hasAuthorship W4313389046A5078752558 @default.
• W4313389046 hasAuthorship W4313389046A5080354069 @default.
• W4313389046 hasAuthorship W4313389046A5081342993 @default.
• W4313389046 hasBestOaLocation W43133890461 @default.
• W4313389046 hasConcept C112672928 @default.
• W4313389046 hasConcept C126322002 @default.
• W4313389046 hasConcept C134018914 @default.
• W4313389046 hasConcept C143121216 @default.
• W4313389046 hasConcept C172680121 @default.
• W4313389046 hasConcept C2777165150 @default.
• W4313389046 hasConcept C2778780700 @default.
• W4313389046 hasConcept C2779234561 @default.
• W4313389046 hasConcept C42407357 @default.
• W4313389046 hasConcept C54355233 @default.
• W4313389046 hasConcept C60644358 @default.
• W4313389046 hasConcept C71924100 @default.
• W4313389046 hasConcept C86803240 @default.
• W4313389046 hasConceptScore W4313389046C112672928 @default.
• W4313389046 hasConceptScore W4313389046C126322002 @default.
• W4313389046 hasConceptScore W4313389046C134018914 @default.
• W4313389046 hasConceptScore W4313389046C143121216 @default.
• W4313389046 hasConceptScore W4313389046C172680121 @default.
• W4313389046 hasConceptScore W4313389046C2777165150 @default.
• W4313389046 hasConceptScore W4313389046C2778780700 @default.
• W4313389046 hasConceptScore W4313389046C2779234561 @default.
• W4313389046 hasConceptScore W4313389046C42407357 @default.
• W4313389046 hasConceptScore W4313389046C54355233 @default.
• W4313389046 hasConceptScore W4313389046C60644358 @default.
• W4313389046 hasConceptScore W4313389046C71924100 @default.
• W4313389046 hasConceptScore W4313389046C86803240 @default.
• W4313389046 hasIssue "1" @default.
• W4313389046 hasLocation W43133890461 @default.
• W4313389046 hasLocation W43133890462 @default.

• next