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- W4313389629 abstract "Ribonucleic acid (RNA) methylation is the most abundant modification in biological systems, accounting for 60% of all RNA modifications, and affects multiple aspects of RNA (including mRNAs, tRNAs, rRNAs, microRNAs, and long non-coding RNAs). Dysregulation of RNA methylation causes many developmental diseases through various mechanisms mediated by N6-methyladenosine (m6A), 5-methylcytosine (m5C), N1-methyladenosine (m1A), 5-hydroxymethylcytosine (hm5C), and pseudouridine (Ψ). The emerging tools of RNA methylation can be used as diagnostic, preventive, and therapeutic markers. Here, we review the accumulated discoveries to date regarding the biological function and dynamic regulation of RNA methylation/modification, as well as the most popularly used techniques applied for profiling RNA epitranscriptome, to provide new ideas for growth and development." @default.
- W4313389629 created "2023-01-06" @default.
- W4313389629 creator A5007638880 @default.
- W4313389629 creator A5012326224 @default.
- W4313389629 creator A5027890999 @default.
- W4313389629 creator A5039583856 @default.
- W4313389629 creator A5043763518 @default.
- W4313389629 creator A5053778819 @default.
- W4313389629 creator A5055355201 @default.
- W4313389629 creator A5081767386 @default.
- W4313389629 date "2022-12-19" @default.
- W4313389629 modified "2023-10-01" @default.
- W4313389629 title "Dynamic regulation and key roles of ribonucleic acid methylation" @default.
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