Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313395931> ?p ?o ?g. }
- W4313395931 abstract "Since ancient times, plants have been an extensive reservoir of bioactive compounds with therapeutic interest for new drug development and clinical application. Cucurbitacins are a compelling example of these drug leads, primarily present in the plant kingdom, especially in the Cucurbitaceae family. However, these natural compounds are also known in several genera within other plant families. Beyond the Cucurbitaceae family, they are also present in other plant families, as well as in some fungi and one shell-less marine mollusc. Despite the natural abundance of cucurbitacins in different natural species, their obtaining and isolation is limited, as a result, an increase in their chemical synthesis has been developed by researchers. Data on cucurbitacins and their anticancer activities were collected from databases such as PubMed/MedLine, TRIP database, Web of Science, Google Scholar, and ScienceDirect and the information was arranged sequentially for a better understanding of the antitumor potential. The results of the studies showed that cucurbitacins have significant biological activities, such as anti-inflammatory, antioxidant, antimalarial, antimicrobial, hepatoprotective and antitumor potential. In conclusion, there are several studies, both in vitro and in vivo reporting this important anticancer/chemopreventive potential; hence a comprehensive review on this topic is recommended for future clinical research." @default.
- W4313395931 created "2023-01-06" @default.
- W4313395931 creator A5005776482 @default.
- W4313395931 creator A5031414247 @default.
- W4313395931 creator A5046438933 @default.
- W4313395931 creator A5057807839 @default.
- W4313395931 creator A5060571806 @default.
- W4313395931 creator A5084977528 @default.
- W4313395931 creator A5087584023 @default.
- W4313395931 date "2022-12-31" @default.
- W4313395931 modified "2023-10-05" @default.
- W4313395931 title "Cucurbitacins as potential anticancer agents: new insights on molecular mechanisms" @default.
- W4313395931 cites W1116726549 @default.
- W4313395931 cites W1175058880 @default.
- W4313395931 cites W1507146289 @default.
- W4313395931 cites W1679995123 @default.
- W4313395931 cites W1734492143 @default.
- W4313395931 cites W1746633512 @default.
- W4313395931 cites W1861416158 @default.
- W4313395931 cites W193720445 @default.
- W4313395931 cites W1964908039 @default.
- W4313395931 cites W1967602624 @default.
- W4313395931 cites W1970696394 @default.
- W4313395931 cites W2004154588 @default.
- W4313395931 cites W2005220030 @default.
- W4313395931 cites W2011104248 @default.
- W4313395931 cites W2022961915 @default.
- W4313395931 cites W2024486784 @default.
- W4313395931 cites W2035633811 @default.
- W4313395931 cites W2040804147 @default.
- W4313395931 cites W2042773419 @default.
- W4313395931 cites W2049339580 @default.
- W4313395931 cites W2060214311 @default.
- W4313395931 cites W2060408030 @default.
- W4313395931 cites W2077612782 @default.
- W4313395931 cites W2080620198 @default.
- W4313395931 cites W2083996156 @default.
- W4313395931 cites W2091615501 @default.
- W4313395931 cites W211081217 @default.
- W4313395931 cites W2151154588 @default.
- W4313395931 cites W2167406365 @default.
- W4313395931 cites W2171909437 @default.
- W4313395931 cites W2284639409 @default.
- W4313395931 cites W2318144603 @default.
- W4313395931 cites W2326754484 @default.
- W4313395931 cites W2328845811 @default.
- W4313395931 cites W2334019395 @default.
- W4313395931 cites W2338742608 @default.
- W4313395931 cites W2505534429 @default.
- W4313395931 cites W2507931606 @default.
- W4313395931 cites W2551890016 @default.
- W4313395931 cites W2555729922 @default.
- W4313395931 cites W2576531821 @default.
- W4313395931 cites W2613305072 @default.
- W4313395931 cites W2614407356 @default.
- W4313395931 cites W2616787413 @default.
- W4313395931 cites W2761901713 @default.
- W4313395931 cites W2763315117 @default.
- W4313395931 cites W2785453685 @default.
- W4313395931 cites W2889811282 @default.
- W4313395931 cites W2892342148 @default.
- W4313395931 cites W2897139941 @default.
- W4313395931 cites W2903662299 @default.
- W4313395931 cites W2910732688 @default.
- W4313395931 cites W2916171427 @default.
- W4313395931 cites W2923048941 @default.
- W4313395931 cites W2946516685 @default.
- W4313395931 cites W2951976762 @default.
- W4313395931 cites W2954465786 @default.
- W4313395931 cites W2988509343 @default.
- W4313395931 cites W3000530464 @default.
- W4313395931 cites W3004954692 @default.
- W4313395931 cites W3005817142 @default.
- W4313395931 cites W3011890252 @default.
- W4313395931 cites W3025753630 @default.
- W4313395931 cites W3033479257 @default.
- W4313395931 cites W3046573466 @default.
- W4313395931 cites W3080974359 @default.
- W4313395931 cites W3082953136 @default.
- W4313395931 cites W3085839124 @default.
- W4313395931 cites W3087779093 @default.
- W4313395931 cites W3092479010 @default.
- W4313395931 cites W3094263302 @default.
- W4313395931 cites W3097814636 @default.
- W4313395931 cites W3119018587 @default.
- W4313395931 cites W3127176917 @default.
- W4313395931 cites W3138611680 @default.
- W4313395931 cites W3144582869 @default.
- W4313395931 cites W3145282922 @default.
- W4313395931 cites W3161674658 @default.
- W4313395931 cites W3173169652 @default.
- W4313395931 cites W3181530391 @default.
- W4313395931 cites W3191435814 @default.
- W4313395931 cites W3191712277 @default.
- W4313395931 cites W3194664104 @default.
- W4313395931 cites W3195691455 @default.
- W4313395931 cites W3205724362 @default.
- W4313395931 cites W4200286924 @default.
- W4313395931 cites W4200303216 @default.
- W4313395931 cites W4206506150 @default.