Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313397763> ?p ?o ?g. }
- W4313397763 endingPage "350" @default.
- W4313397763 startingPage "350" @default.
- W4313397763 abstract "Remifentanil is widely used for intraoperative analgesia, but often causes remifentanil-induced hyperalgesia (RIH) and related side effects. Dexmedetomidine, a non-opioid analgesic, has been used as an alternative to remifentanil to prevent RIH. We aimed to investigate the effect of dexmedetomidine on postoperative recovery after gynecological laparoscopy. Ninety-six adult patients undergoing elective gynecological laparoscopy were randomly assigned to the dexmedetomidine or remifentanil groups. The primary outcome was the pain score at 30 min after surgery. The secondary outcomes were intraoperative adverse events (hypotension and bradycardia) and postoperative opioid-related side effects (nausea, vomiting, requirement for rescue analgesics, and shivering). We also performed an ancillary cytokine study to evaluate oxidative stress, one of the causes of RIH. Compared with the remifentanil group, the dexmedetomidine group had lower pain scores at 30 min after surgery (4.0 ± 1.9 vs. 6.1 ± 2.0, mean ± SD, p < 0.001) and lower incidence of intraoperative hypotension and postoperative nausea, vomiting, and shivering. Furthermore, the proportion of patients requiring rescue analgesics was significantly lower in the dexmedetomidine than in the remifentanil group (25% vs. 66.7%, p < 0.001). Cytokine levels did not differ between the groups. Dexmedetomidine showed a better analgesic effect with minimal opioid-related side effects and is considered superior to remifentanil for intraoperative analgesia." @default.
- W4313397763 created "2023-01-06" @default.
- W4313397763 creator A5010794653 @default.
- W4313397763 creator A5016434842 @default.
- W4313397763 creator A5075564134 @default.
- W4313397763 creator A5087437220 @default.
- W4313397763 date "2023-01-02" @default.
- W4313397763 modified "2023-09-25" @default.
- W4313397763 title "Efficacy of Dexmedetomidine vs. Remifentanil for Postoperative Analgesia and Opioid-Related Side Effects after Gynecological Laparoscopy: A Prospective Randomized Controlled Trial" @default.
- W4313397763 cites W1568700608 @default.
- W4313397763 cites W1987825791 @default.
- W4313397763 cites W2012358876 @default.
- W4313397763 cites W2110769281 @default.
- W4313397763 cites W2120539545 @default.
- W4313397763 cites W2135807693 @default.
- W4313397763 cites W2140345929 @default.
- W4313397763 cites W2185945670 @default.
- W4313397763 cites W2327336736 @default.
- W4313397763 cites W2519954174 @default.
- W4313397763 cites W2536543718 @default.
- W4313397763 cites W2542501077 @default.
- W4313397763 cites W2576234460 @default.
- W4313397763 cites W2586241300 @default.
- W4313397763 cites W2744987843 @default.
- W4313397763 cites W2774402685 @default.
- W4313397763 cites W2774917626 @default.
- W4313397763 cites W2782308780 @default.
- W4313397763 cites W2795673697 @default.
- W4313397763 cites W2889228657 @default.
- W4313397763 cites W2892836665 @default.
- W4313397763 cites W2932185501 @default.
- W4313397763 cites W2990771434 @default.
- W4313397763 cites W3032295650 @default.
- W4313397763 cites W3089887531 @default.
- W4313397763 cites W3127698804 @default.
- W4313397763 cites W3131587736 @default.
- W4313397763 cites W3175875083 @default.
- W4313397763 cites W3192141250 @default.
- W4313397763 cites W3214526217 @default.
- W4313397763 cites W4247215665 @default.
- W4313397763 doi "https://doi.org/10.3390/jcm12010350" @default.
- W4313397763 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36615151" @default.
- W4313397763 hasPublicationYear "2023" @default.
- W4313397763 type Work @default.
- W4313397763 citedByCount "1" @default.
- W4313397763 countsByYear W43133977632023 @default.
- W4313397763 crossrefType "journal-article" @default.
- W4313397763 hasAuthorship W4313397763A5010794653 @default.
- W4313397763 hasAuthorship W4313397763A5016434842 @default.
- W4313397763 hasAuthorship W4313397763A5075564134 @default.
- W4313397763 hasAuthorship W4313397763A5087437220 @default.
- W4313397763 hasBestOaLocation W43133977631 @default.
- W4313397763 hasConcept C126322002 @default.
- W4313397763 hasConcept C141071460 @default.
- W4313397763 hasConcept C170493617 @default.
- W4313397763 hasConcept C2776277131 @default.
- W4313397763 hasConcept C2776814716 @default.
- W4313397763 hasConcept C2777297131 @default.
- W4313397763 hasConcept C2778891214 @default.
- W4313397763 hasConcept C2780580376 @default.
- W4313397763 hasConcept C2780820201 @default.
- W4313397763 hasConcept C2780852908 @default.
- W4313397763 hasConcept C2781063702 @default.
- W4313397763 hasConcept C2781258859 @default.
- W4313397763 hasConcept C2781302539 @default.
- W4313397763 hasConcept C42219234 @default.
- W4313397763 hasConcept C71924100 @default.
- W4313397763 hasConceptScore W4313397763C126322002 @default.
- W4313397763 hasConceptScore W4313397763C141071460 @default.
- W4313397763 hasConceptScore W4313397763C170493617 @default.
- W4313397763 hasConceptScore W4313397763C2776277131 @default.
- W4313397763 hasConceptScore W4313397763C2776814716 @default.
- W4313397763 hasConceptScore W4313397763C2777297131 @default.
- W4313397763 hasConceptScore W4313397763C2778891214 @default.
- W4313397763 hasConceptScore W4313397763C2780580376 @default.
- W4313397763 hasConceptScore W4313397763C2780820201 @default.
- W4313397763 hasConceptScore W4313397763C2780852908 @default.
- W4313397763 hasConceptScore W4313397763C2781063702 @default.
- W4313397763 hasConceptScore W4313397763C2781258859 @default.
- W4313397763 hasConceptScore W4313397763C2781302539 @default.
- W4313397763 hasConceptScore W4313397763C42219234 @default.
- W4313397763 hasConceptScore W4313397763C71924100 @default.
- W4313397763 hasIssue "1" @default.
- W4313397763 hasLocation W43133977631 @default.
- W4313397763 hasLocation W43133977632 @default.
- W4313397763 hasLocation W43133977633 @default.
- W4313397763 hasOpenAccess W4313397763 @default.
- W4313397763 hasPrimaryLocation W43133977631 @default.
- W4313397763 hasRelatedWork W1493094451 @default.
- W4313397763 hasRelatedWork W1556227024 @default.
- W4313397763 hasRelatedWork W2347217249 @default.
- W4313397763 hasRelatedWork W2351238419 @default.
- W4313397763 hasRelatedWork W2431564509 @default.
- W4313397763 hasRelatedWork W2584329216 @default.
- W4313397763 hasRelatedWork W2890150312 @default.
- W4313397763 hasRelatedWork W3031539190 @default.
- W4313397763 hasRelatedWork W4319021915 @default.
- W4313397763 hasRelatedWork W50876771 @default.