Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313397908> ?p ?o ?g. }
- W4313397908 endingPage "101741" @default.
- W4313397908 startingPage "101741" @default.
- W4313397908 abstract "Upper airway (UA) collapsibility is one of the key factors that determine the severity of obstructive sleep apnea (OSA). Interventions for OSA are aimed at reducing UA collapsibility, but selecting the optimal alternative intervention for patients who fail CPAP is challenging because currently no validated method predicts how anatomical changes affect UA collapsibility. The gold standard objective measure of UA collapsibility is the pharyngeal critical pressure (Pcrit). A systematic literature review and meta-analysis were performed to identify the anatomical factors with the strongest correlation with Pcrit. A search using the PRISMA methodology was performed on PubMed for English language scientific papers that correlated Pcrit to anatomic variables and OSA severity as measured by the apnea-hypopnea index (AHI). A total of 29 papers that matched eligibility criteria were included in the quantitative synthesis. The meta-analysis suggested that AHI has only a moderate correlation with Pcrit (estimated Pearson correlation coefficient r = 0.46). The meta-analysis identified four key anatomical variables associated with UA collapsibility, namely hyoid position (r = 0.53), tongue volume (r = 0.51), pharyngeal length (r = 0.50), and waist circumference (r = 0.49). In the future, biomechanical models that quantify the relative importance of these anatomical factors in determining UA collapsibility may help identify the optimal intervention for each patient. Many anatomical and structural factors such as airspace cross-sectional areas, epiglottic collapse, and palatal prolapse have inadequate data and require further research." @default.
- W4313397908 created "2023-01-06" @default.
- W4313397908 creator A5025430320 @default.
- W4313397908 creator A5032026956 @default.
- W4313397908 creator A5035937945 @default.
- W4313397908 creator A5044087253 @default.
- W4313397908 creator A5047483977 @default.
- W4313397908 creator A5084631368 @default.
- W4313397908 creator A5085878974 @default.
- W4313397908 creator A5087087768 @default.
- W4313397908 date "2023-04-01" @default.
- W4313397908 modified "2023-10-14" @default.
- W4313397908 title "Anatomical determinants of upper airway collapsibility in obstructive sleep apnea: A systematic review and meta-analysis" @default.
- W4313397908 cites W1003815757 @default.
- W4313397908 cites W1127604872 @default.
- W4313397908 cites W1517452345 @default.
- W4313397908 cites W1599833705 @default.
- W4313397908 cites W1750841216 @default.
- W4313397908 cites W1869035511 @default.
- W4313397908 cites W1936216280 @default.
- W4313397908 cites W1945543071 @default.
- W4313397908 cites W1965569267 @default.
- W4313397908 cites W1966890503 @default.
- W4313397908 cites W1981176325 @default.
- W4313397908 cites W1983589524 @default.
- W4313397908 cites W1987680533 @default.
- W4313397908 cites W1988402911 @default.
- W4313397908 cites W1989666564 @default.
- W4313397908 cites W1992683816 @default.
- W4313397908 cites W1993964196 @default.
- W4313397908 cites W1995806795 @default.
- W4313397908 cites W1997698146 @default.
- W4313397908 cites W2004332439 @default.
- W4313397908 cites W2009479462 @default.
- W4313397908 cites W2016141754 @default.
- W4313397908 cites W2019412274 @default.
- W4313397908 cites W2033591954 @default.
- W4313397908 cites W2034657656 @default.
- W4313397908 cites W2040540404 @default.
- W4313397908 cites W2041691732 @default.
- W4313397908 cites W2044646965 @default.
- W4313397908 cites W2048663736 @default.
- W4313397908 cites W2049959832 @default.
- W4313397908 cites W2051307462 @default.
- W4313397908 cites W2053638800 @default.
- W4313397908 cites W2056055232 @default.
- W4313397908 cites W2056793793 @default.
- W4313397908 cites W2065808972 @default.
- W4313397908 cites W2067361424 @default.
- W4313397908 cites W2081030398 @default.
- W4313397908 cites W2082847780 @default.
- W4313397908 cites W2097180254 @default.
- W4313397908 cites W2097207628 @default.
- W4313397908 cites W2098113164 @default.
- W4313397908 cites W2100065541 @default.
- W4313397908 cites W2102259108 @default.
- W4313397908 cites W2108241504 @default.
- W4313397908 cites W2110386263 @default.
- W4313397908 cites W2110666037 @default.
- W4313397908 cites W2110768240 @default.
- W4313397908 cites W2110980488 @default.
- W4313397908 cites W2112616328 @default.
- W4313397908 cites W2114034451 @default.
- W4313397908 cites W2116319702 @default.
- W4313397908 cites W2124912614 @default.
- W4313397908 cites W2127297361 @default.
- W4313397908 cites W2127577115 @default.
- W4313397908 cites W2132249730 @default.
- W4313397908 cites W2132327194 @default.
- W4313397908 cites W2138326686 @default.
- W4313397908 cites W2145682509 @default.
- W4313397908 cites W2151961444 @default.
- W4313397908 cites W2152836754 @default.
- W4313397908 cites W2157308124 @default.
- W4313397908 cites W2159177443 @default.
- W4313397908 cites W2159450103 @default.
- W4313397908 cites W2161374186 @default.
- W4313397908 cites W2161786477 @default.
- W4313397908 cites W2162645075 @default.
- W4313397908 cites W2171722070 @default.
- W4313397908 cites W2172242816 @default.
- W4313397908 cites W2187573380 @default.
- W4313397908 cites W2241096385 @default.
- W4313397908 cites W2336763056 @default.
- W4313397908 cites W2400483924 @default.
- W4313397908 cites W2505163891 @default.
- W4313397908 cites W2559057859 @default.
- W4313397908 cites W2765643702 @default.
- W4313397908 cites W2788947442 @default.
- W4313397908 cites W2793350103 @default.
- W4313397908 cites W2888479110 @default.
- W4313397908 cites W2913066228 @default.
- W4313397908 cites W2913385080 @default.
- W4313397908 cites W2963742266 @default.
- W4313397908 cites W2968409227 @default.
- W4313397908 cites W2999098554 @default.
- W4313397908 cites W3005295220 @default.
- W4313397908 cites W3007480820 @default.