Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313397962> ?p ?o ?g. }
- W4313397962 endingPage "108373" @default.
- W4313397962 startingPage "108373" @default.
- W4313397962 abstract "A miniaturized clean-up and preconcentration procedure involving deep eutectic solvent-based solidified floating organic drop microextraction was developed for the determination of melatonin in pharmaceuticals and dietary supplements by high-performance liquid chromatography with UV detection. Melatonin is widely used for the treatment of a large spectrum of diseases, and many studies have focused on its efficacy in reducing COVID-19 severity. For the first time, various hydrophobic deep eutectic solvents based on menthol, medium-chain fatty acids, and long-chain alcohols were studied for the microextraction of melatonin. Among the studied solvents, the deep eutectic solvent based on menthol and heptanoic acid provided the highest extraction recovery (90 %). In the developed procedure, a flat magnetic stirrer bar was covered by a microliter amount of the deep eutectic solvent and the sample solution was added under magnetic stirring. In this case, the deep eutectic solvent phase was easily dispersed into the aqueous phase without the use of any organic disperser solvents, resulting in fast analyte extraction (1 min). In the absence of stirring, the aggregation of extract as a floating drop on the surface of the aqueous phase was observed immediately. The low melting/freezing point and low density of the extraction solvent compared with water allowed one to quickly and easily retrieve a low volume of extract (25 μL) in a microextraction procedure by solidification. Validation of the procedure showed that limits of detection and quantification, calculated from the blank tests based on 3σ and 10 σ, were 0.003 mg g−1 and 0.01 mg g−1, respectively." @default.
- W4313397962 created "2023-01-06" @default.
- W4313397962 creator A5019989686 @default.
- W4313397962 creator A5025746353 @default.
- W4313397962 creator A5031041740 @default.
- W4313397962 creator A5042378068 @default.
- W4313397962 creator A5053260617 @default.
- W4313397962 creator A5065300133 @default.
- W4313397962 creator A5077048755 @default.
- W4313397962 date "2023-04-01" @default.
- W4313397962 modified "2023-09-30" @default.
- W4313397962 title "Solidified floating organic drop microextraction procedure based on deep eutectic solvent for the determination of melatonin in pharmaceuticals and dietary supplements" @default.
- W4313397962 cites W1994303960 @default.
- W4313397962 cites W2003303885 @default.
- W4313397962 cites W2012742245 @default.
- W4313397962 cites W2022496632 @default.
- W4313397962 cites W2044392760 @default.
- W4313397962 cites W2079186700 @default.
- W4313397962 cites W2099966661 @default.
- W4313397962 cites W2128344161 @default.
- W4313397962 cites W2150891560 @default.
- W4313397962 cites W2168606002 @default.
- W4313397962 cites W2345770077 @default.
- W4313397962 cites W2528910637 @default.
- W4313397962 cites W2553285007 @default.
- W4313397962 cites W2588410624 @default.
- W4313397962 cites W2606092322 @default.
- W4313397962 cites W2610909132 @default.
- W4313397962 cites W2622932237 @default.
- W4313397962 cites W2739732315 @default.
- W4313397962 cites W2768233539 @default.
- W4313397962 cites W2798084432 @default.
- W4313397962 cites W2886530960 @default.
- W4313397962 cites W2946926745 @default.
- W4313397962 cites W3012251673 @default.
- W4313397962 cites W3021615684 @default.
- W4313397962 cites W3035506582 @default.
- W4313397962 cites W3082634831 @default.
- W4313397962 cites W3130487627 @default.
- W4313397962 cites W3137610652 @default.
- W4313397962 cites W3149627720 @default.
- W4313397962 cites W3202409002 @default.
- W4313397962 cites W4206547451 @default.
- W4313397962 cites W4206569775 @default.
- W4313397962 cites W4220821386 @default.
- W4313397962 cites W4220929912 @default.
- W4313397962 cites W4224909622 @default.
- W4313397962 cites W4280637261 @default.
- W4313397962 cites W621525991 @default.
- W4313397962 doi "https://doi.org/10.1016/j.microc.2022.108373" @default.
- W4313397962 hasPublicationYear "2023" @default.
- W4313397962 type Work @default.
- W4313397962 citedByCount "6" @default.
- W4313397962 countsByYear W43133979622023 @default.
- W4313397962 crossrefType "journal-article" @default.
- W4313397962 hasAuthorship W4313397962A5019989686 @default.
- W4313397962 hasAuthorship W4313397962A5025746353 @default.
- W4313397962 hasAuthorship W4313397962A5031041740 @default.
- W4313397962 hasAuthorship W4313397962A5042378068 @default.
- W4313397962 hasAuthorship W4313397962A5053260617 @default.
- W4313397962 hasAuthorship W4313397962A5065300133 @default.
- W4313397962 hasAuthorship W4313397962A5077048755 @default.
- W4313397962 hasConcept C149556010 @default.
- W4313397962 hasConcept C159985019 @default.
- W4313397962 hasConcept C178790620 @default.
- W4313397962 hasConcept C18168003 @default.
- W4313397962 hasConcept C184651966 @default.
- W4313397962 hasConcept C185592680 @default.
- W4313397962 hasConcept C192562407 @default.
- W4313397962 hasConcept C2775964210 @default.
- W4313397962 hasConcept C2780026712 @default.
- W4313397962 hasConcept C2780371645 @default.
- W4313397962 hasConcept C2780471494 @default.
- W4313397962 hasConcept C2781345722 @default.
- W4313397962 hasConcept C41008148 @default.
- W4313397962 hasConcept C43617362 @default.
- W4313397962 hasConcept C4725764 @default.
- W4313397962 hasConcept C76155785 @default.
- W4313397962 hasConceptScore W4313397962C149556010 @default.
- W4313397962 hasConceptScore W4313397962C159985019 @default.
- W4313397962 hasConceptScore W4313397962C178790620 @default.
- W4313397962 hasConceptScore W4313397962C18168003 @default.
- W4313397962 hasConceptScore W4313397962C184651966 @default.
- W4313397962 hasConceptScore W4313397962C185592680 @default.
- W4313397962 hasConceptScore W4313397962C192562407 @default.
- W4313397962 hasConceptScore W4313397962C2775964210 @default.
- W4313397962 hasConceptScore W4313397962C2780026712 @default.
- W4313397962 hasConceptScore W4313397962C2780371645 @default.
- W4313397962 hasConceptScore W4313397962C2780471494 @default.
- W4313397962 hasConceptScore W4313397962C2781345722 @default.
- W4313397962 hasConceptScore W4313397962C41008148 @default.
- W4313397962 hasConceptScore W4313397962C43617362 @default.
- W4313397962 hasConceptScore W4313397962C4725764 @default.
- W4313397962 hasConceptScore W4313397962C76155785 @default.
- W4313397962 hasFunder F4320322515 @default.
- W4313397962 hasFunder F4320324099 @default.
- W4313397962 hasLocation W43133979621 @default.
- W4313397962 hasOpenAccess W4313397962 @default.