Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313402223> ?p ?o ?g. }
- W4313402223 endingPage "69" @default.
- W4313402223 startingPage "69" @default.
- W4313402223 abstract "Imaging tumor microenvironments such as hypoxia, oxygenation, redox status, and/or glycolytic metabolism in tissues/cells is useful for diagnostic and prognostic purposes. New imaging modalities are under development for imaging various aspects of tumor microenvironments. Electron Paramagnetic Resonance Imaging (EPRI) though similar to NMR/MRI is unique in its ability to provide quantitative images of pO2 in vivo. The short electron spin relaxation times have been posing formidable challenge to the technology development for clinical application. With the availability of the narrow line width trityl compounds, pulsed EPR imaging techniques were developed for pO2 imaging. EPRI visualizes the exogenously administered spin probes/contrast agents and hence lacks the complementary morphological information. Dynamic nuclear polarization (DNP), a phenomenon that transfers the high electron spin polarization to the surrounding nuclear spins (1H and 13C) opened new capabilities in molecular imaging. DNP of 13C nuclei is utilized in metabolic imaging of 13C-labeled compounds by imaging specific enzyme kinetics. In this article, imaging strategies mapping physiologic and metabolic aspects in vivo are reviewed within the framework of their application in cancer research, highlighting the potential and challenges of each of them." @default.
- W4313402223 created "2023-01-06" @default.
- W4313402223 creator A5011980329 @default.
- W4313402223 creator A5061175261 @default.
- W4313402223 creator A5066739882 @default.
- W4313402223 creator A5076638374 @default.
- W4313402223 creator A5081250782 @default.
- W4313402223 creator A5088030244 @default.
- W4313402223 creator A5090075053 @default.
- W4313402223 date "2023-01-01" @default.
- W4313402223 modified "2023-09-30" @default.
- W4313402223 title "EPR and Related Magnetic Resonance Imaging Techniques in Cancer Research" @default.
- W4313402223 cites W1177677115 @default.
- W4313402223 cites W1951465258 @default.
- W4313402223 cites W1952550263 @default.
- W4313402223 cites W1966418998 @default.
- W4313402223 cites W1967109061 @default.
- W4313402223 cites W1967470344 @default.
- W4313402223 cites W1968503556 @default.
- W4313402223 cites W1971900055 @default.
- W4313402223 cites W1975822731 @default.
- W4313402223 cites W1977612780 @default.
- W4313402223 cites W1979126926 @default.
- W4313402223 cites W1984695912 @default.
- W4313402223 cites W1986757721 @default.
- W4313402223 cites W1989690974 @default.
- W4313402223 cites W1989803926 @default.
- W4313402223 cites W1994291555 @default.
- W4313402223 cites W1997701630 @default.
- W4313402223 cites W2002497476 @default.
- W4313402223 cites W2004128856 @default.
- W4313402223 cites W2004702412 @default.
- W4313402223 cites W2007856779 @default.
- W4313402223 cites W2008125272 @default.
- W4313402223 cites W2008844781 @default.
- W4313402223 cites W2008995145 @default.
- W4313402223 cites W2011482669 @default.
- W4313402223 cites W2014341923 @default.
- W4313402223 cites W2014483643 @default.
- W4313402223 cites W2016200811 @default.
- W4313402223 cites W2018939432 @default.
- W4313402223 cites W2020079102 @default.
- W4313402223 cites W2020623316 @default.
- W4313402223 cites W2024383450 @default.
- W4313402223 cites W2026921059 @default.
- W4313402223 cites W2026991038 @default.
- W4313402223 cites W2028111455 @default.
- W4313402223 cites W2030865698 @default.
- W4313402223 cites W2032616868 @default.
- W4313402223 cites W2034249223 @default.
- W4313402223 cites W2034920804 @default.
- W4313402223 cites W2036947314 @default.
- W4313402223 cites W2038992272 @default.
- W4313402223 cites W2041880997 @default.
- W4313402223 cites W2042989397 @default.
- W4313402223 cites W2043019999 @default.
- W4313402223 cites W2046391858 @default.
- W4313402223 cites W2047054929 @default.
- W4313402223 cites W2052051935 @default.
- W4313402223 cites W2055014723 @default.
- W4313402223 cites W2057978013 @default.
- W4313402223 cites W2058284211 @default.
- W4313402223 cites W2058512505 @default.
- W4313402223 cites W2058780251 @default.
- W4313402223 cites W2059900570 @default.
- W4313402223 cites W2060853527 @default.
- W4313402223 cites W2063505712 @default.
- W4313402223 cites W2068846208 @default.
- W4313402223 cites W2071714163 @default.
- W4313402223 cites W2073813993 @default.
- W4313402223 cites W2074040223 @default.
- W4313402223 cites W2077401502 @default.
- W4313402223 cites W2078236205 @default.
- W4313402223 cites W2082993111 @default.
- W4313402223 cites W2085565081 @default.
- W4313402223 cites W2091723288 @default.
- W4313402223 cites W2097259163 @default.
- W4313402223 cites W2103681669 @default.
- W4313402223 cites W2111593155 @default.
- W4313402223 cites W2116874594 @default.
- W4313402223 cites W2120342757 @default.
- W4313402223 cites W2121669013 @default.
- W4313402223 cites W2132677826 @default.
- W4313402223 cites W2144904402 @default.
- W4313402223 cites W2153912174 @default.
- W4313402223 cites W2156620240 @default.
- W4313402223 cites W2157854449 @default.
- W4313402223 cites W2159557216 @default.
- W4313402223 cites W2160810259 @default.
- W4313402223 cites W2162214261 @default.
- W4313402223 cites W2163537171 @default.
- W4313402223 cites W2175724880 @default.
- W4313402223 cites W2276951999 @default.
- W4313402223 cites W2409163903 @default.
- W4313402223 cites W2416033676 @default.
- W4313402223 cites W2739560120 @default.
- W4313402223 cites W2763289590 @default.
- W4313402223 cites W2768248787 @default.