FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313402822> ?p ?o ?g. }

• W4313402822 abstract "Abstract Background Depression is an important public health burden, vitamin D deficiency is associated with mood disorders. The risk of depression may increase with increasing age. Serum vitamin D levels and age are closely related. Objective This study is to investigate the association between vitamin D deficiency, age, and depression in a representative sample of US adults and the combined effect of vitamin D deficiency and aging on depression. Materials and Methods We extracted data from NHANES 2013–2018, including demographic characteristics, depression level, vitamin D level, physical activity, and body measures. Depression was screened by PHQ-9. Vitamin D was measured using the CDC method (test principle utilizing high performance liquid chromatography-tandem mass spectrometry to quantify 25OHD3, epi-25OHD3 and 25OHD2 in human serum). We performed binary logistic regression models to analyze the association between vitamin D, age and depression, respectively. Results A total of 15156 adults aged 20 years or older (mean age 49.81 ± 17.67 years, 7301 males and 7855 females) were included. Vitamin D levels were negatively associated with depression ( P < 0.001). Vitamin D had a significant effect on depression (OR = 0.776, 95%Cl: 0.682–0.884, P < 0.001), the effect remained significant after adjusted for confounding variables (OR = 0.761, 95%Cl: 0.663–0.874, P < 0.001). Age was positively associated with depression ( P < 0.001) and had a significant effect on depression (OR = 1.079, 95%Cl: 1.032–1.128, P = 0.001), the effect remained significant after adjusted for confounding variables (OR = 1.085, 95%Cl: 1.034–1.138, P = 0.001). Age and vitamin D levels were positively correlated ( P < 0.001), and aging had a significant effect on vitamin D level (OR = 1.526, 95%Cl: 1.416–1.645, P < 0.001), the effect remained significant after adjusted for confounding variables (OR = 1.371, 95%Cl: 1.263–1.487, P < 0.001). In addition, the detection rate of depression was higher in females (2312/7855, 29.43%) than in males (1571/7301, 21.52%), and the difference was statistically significant ( P < 0.001). Conclusions Vitamin D deficiency is a risk factor for depression; aging is a protective factor for vitamin D deficiency; Vitamin D and age synergetically affect the incident risk of depression: younger populations are more likely to present an increased risk of depression due to vitamin D deficiency; elderly females who are unmarried and living alone are the highest risk group for depression." @default.
• W4313402822 created "2023-01-06" @default.
• W4313402822 creator A5011563523 @default.
• W4313402822 creator A5021163747 @default.
• W4313402822 creator A5022346330 @default.
• W4313402822 creator A5030509837 @default.
• W4313402822 creator A5038805449 @default.
• W4313402822 creator A5048352764 @default.
• W4313402822 creator A5089838560 @default.
• W4313402822 creator A5090095845 @default.
• W4313402822 date "2022-12-19" @default.
• W4313402822 modified "2023-10-14" @default.
• W4313402822 title "The Association of Vitamin D Deficiency, Age and Depression in US Adults: A Cross-Sectional Analysis" @default.
• W4313402822 cites W1739556717 @default.
• W4313402822 cites W1922178820 @default.
• W4313402822 cites W1970606744 @default.
• W4313402822 cites W1993155490 @default.
• W4313402822 cites W1994676183 @default.
• W4313402822 cites W1996288716 @default.
• W4313402822 cites W2023681059 @default.
• W4313402822 cites W2041295884 @default.
• W4313402822 cites W2068497137 @default.
• W4313402822 cites W2080427068 @default.
• W4313402822 cites W2096856326 @default.
• W4313402822 cites W2106158410 @default.
• W4313402822 cites W2117590947 @default.
• W4313402822 cites W2132322340 @default.
• W4313402822 cites W2143629083 @default.
• W4313402822 cites W2144533729 @default.
• W4313402822 cites W2147595723 @default.
• W4313402822 cites W2154942788 @default.
• W4313402822 cites W2161480846 @default.
• W4313402822 cites W2259485693 @default.
• W4313402822 cites W2316878322 @default.
• W4313402822 cites W2410673331 @default.
• W4313402822 cites W2410872715 @default.
• W4313402822 cites W2411013142 @default.
• W4313402822 cites W2588900078 @default.
• W4313402822 cites W2786060782 @default.
• W4313402822 cites W2789034326 @default.
• W4313402822 cites W2795647682 @default.
• W4313402822 cites W2942311206 @default.
• W4313402822 cites W2945870252 @default.
• W4313402822 cites W2965255255 @default.
• W4313402822 cites W2967469359 @default.
• W4313402822 cites W2967946137 @default.
• W4313402822 cites W2976799364 @default.
• W4313402822 cites W2998228359 @default.
• W4313402822 cites W3014733548 @default.
• W4313402822 cites W3128080271 @default.
• W4313402822 cites W3128410192 @default.
• W4313402822 cites W3154952393 @default.
• W4313402822 cites W3212982020 @default.
• W4313402822 cites W4295506848 @default.
• W4313402822 doi "https://doi.org/10.21203/rs.3.rs-2349428/v1" @default.
• W4313402822 hasPublicationYear "2022" @default.
• W4313402822 type Work @default.
• W4313402822 citedByCount "0" @default.
• W4313402822 crossrefType "posted-content" @default.
• W4313402822 hasAuthorship W4313402822A5011563523 @default.
• W4313402822 hasAuthorship W4313402822A5021163747 @default.
• W4313402822 hasAuthorship W4313402822A5022346330 @default.
• W4313402822 hasAuthorship W4313402822A5030509837 @default.
• W4313402822 hasAuthorship W4313402822A5038805449 @default.
• W4313402822 hasAuthorship W4313402822A5048352764 @default.
• W4313402822 hasAuthorship W4313402822A5089838560 @default.
• W4313402822 hasAuthorship W4313402822A5090095845 @default.
• W4313402822 hasBestOaLocation W43134028221 @default.
• W4313402822 hasConcept C118552586 @default.
• W4313402822 hasConcept C124490489 @default.
• W4313402822 hasConcept C126322002 @default.
• W4313402822 hasConcept C134018914 @default.
• W4313402822 hasConcept C139719470 @default.
• W4313402822 hasConcept C142052008 @default.
• W4313402822 hasConcept C142724271 @default.
• W4313402822 hasConcept C151956035 @default.
• W4313402822 hasConcept C162324750 @default.
• W4313402822 hasConcept C2776867660 @default.
• W4313402822 hasConcept C2779740938 @default.
• W4313402822 hasConcept C2780733359 @default.
• W4313402822 hasConcept C71924100 @default.
• W4313402822 hasConcept C77350462 @default.
• W4313402822 hasConceptScore W4313402822C118552586 @default.
• W4313402822 hasConceptScore W4313402822C124490489 @default.
• W4313402822 hasConceptScore W4313402822C126322002 @default.
• W4313402822 hasConceptScore W4313402822C134018914 @default.
• W4313402822 hasConceptScore W4313402822C139719470 @default.
• W4313402822 hasConceptScore W4313402822C142052008 @default.
• W4313402822 hasConceptScore W4313402822C142724271 @default.
• W4313402822 hasConceptScore W4313402822C151956035 @default.
• W4313402822 hasConceptScore W4313402822C162324750 @default.
• W4313402822 hasConceptScore W4313402822C2776867660 @default.
• W4313402822 hasConceptScore W4313402822C2779740938 @default.
• W4313402822 hasConceptScore W4313402822C2780733359 @default.
• W4313402822 hasConceptScore W4313402822C71924100 @default.
• W4313402822 hasConceptScore W4313402822C77350462 @default.
• W4313402822 hasLocation W43134028221 @default.
• W4313402822 hasOpenAccess W4313402822 @default.
• W4313402822 hasPrimaryLocation W43134028221 @default.
• W4313402822 hasRelatedWork W141873526 @default.

• next