Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313404361> ?p ?o ?g. }
- W4313404361 endingPage "13010" @default.
- W4313404361 startingPage "13010" @default.
- W4313404361 abstract "Fucoidan, a polymer derived from seaweed, poses a broad range of biological applications, and its potential medicinal benefits have been widely studied over the past decade. In this study, fucoidan was extracted from marine macroalga Sargassum ilicifolium and its bioactive potential for in silico molecular docking was investigated. Additionally, the computational in silico docking studies were applied on the fucoidan against anticancer and antioxidant target proteins by using Glide ligand docking, Schrodinger software. The FT-IR analysis revealed that fucoidan mainly consisted of the fucose residues (59.1%) and a few monosaccharides, such as uronic acid (11.7%) and sulphate (18.3%). The in vitro tests revealed that fucoidan possessed various antioxidative properties and anticoagulant activities. Fucoidans played an inhibitory role in the colony formation of HepG2 cells. The NADPH oxidase (−7.169 Kcal/mol) and cellular tumor antigen p53 protein (−6.205 Kcal/mol) exhibited the highest antioxidant and anticancer proteins, respectively. Overall, the present study results provide a theoretical foundation for broadening the application of fucoidan from S. ilicifolium as a pharmaceutical ingredient." @default.
- W4313404361 created "2023-01-06" @default.
- W4313404361 creator A5011051478 @default.
- W4313404361 creator A5038958143 @default.
- W4313404361 creator A5039737834 @default.
- W4313404361 creator A5040221642 @default.
- W4313404361 creator A5043459440 @default.
- W4313404361 creator A5065087041 @default.
- W4313404361 creator A5089452901 @default.
- W4313404361 date "2022-12-18" @default.
- W4313404361 modified "2023-10-14" @default.
- W4313404361 title "Extraction and Characterization of Fucoidan Derived from Sargassum ilicifolium and Its Biomedical Potential with In Silico Molecular Docking" @default.
- W4313404361 cites W102513336 @default.
- W4313404361 cites W1738299799 @default.
- W4313404361 cites W1774751797 @default.
- W4313404361 cites W1967060830 @default.
- W4313404361 cites W1968834637 @default.
- W4313404361 cites W1976274503 @default.
- W4313404361 cites W1987469049 @default.
- W4313404361 cites W1987674123 @default.
- W4313404361 cites W2004187431 @default.
- W4313404361 cites W2010001103 @default.
- W4313404361 cites W2012991711 @default.
- W4313404361 cites W2013919440 @default.
- W4313404361 cites W2014061043 @default.
- W4313404361 cites W2014424662 @default.
- W4313404361 cites W2015009767 @default.
- W4313404361 cites W2020587056 @default.
- W4313404361 cites W2029101414 @default.
- W4313404361 cites W2029502493 @default.
- W4313404361 cites W2046594010 @default.
- W4313404361 cites W2049287094 @default.
- W4313404361 cites W2052895145 @default.
- W4313404361 cites W2057113434 @default.
- W4313404361 cites W2060740591 @default.
- W4313404361 cites W2068712408 @default.
- W4313404361 cites W2080685777 @default.
- W4313404361 cites W2086808806 @default.
- W4313404361 cites W2091608194 @default.
- W4313404361 cites W2094515560 @default.
- W4313404361 cites W2101709327 @default.
- W4313404361 cites W2120408923 @default.
- W4313404361 cites W2122296266 @default.
- W4313404361 cites W2132589866 @default.
- W4313404361 cites W2133201698 @default.
- W4313404361 cites W2134824140 @default.
- W4313404361 cites W2162004307 @default.
- W4313404361 cites W2162700373 @default.
- W4313404361 cites W2297328657 @default.
- W4313404361 cites W2340630159 @default.
- W4313404361 cites W2402884729 @default.
- W4313404361 cites W2509456181 @default.
- W4313404361 cites W2595884560 @default.
- W4313404361 cites W2605147675 @default.
- W4313404361 cites W2743888139 @default.
- W4313404361 cites W2772943506 @default.
- W4313404361 cites W2789654952 @default.
- W4313404361 cites W2794434156 @default.
- W4313404361 cites W2802444621 @default.
- W4313404361 cites W2807745396 @default.
- W4313404361 cites W2808915569 @default.
- W4313404361 cites W2889201463 @default.
- W4313404361 cites W2899031923 @default.
- W4313404361 cites W2899700163 @default.
- W4313404361 cites W2923248236 @default.
- W4313404361 cites W2946838276 @default.
- W4313404361 cites W2949556875 @default.
- W4313404361 cites W2969500934 @default.
- W4313404361 cites W2985939341 @default.
- W4313404361 cites W2998547181 @default.
- W4313404361 cites W3002532327 @default.
- W4313404361 cites W3012274053 @default.
- W4313404361 cites W3026787770 @default.
- W4313404361 cites W3028140629 @default.
- W4313404361 cites W3114954324 @default.
- W4313404361 cites W3191936266 @default.
- W4313404361 cites W3201998873 @default.
- W4313404361 cites W3211554585 @default.
- W4313404361 cites W4220666941 @default.
- W4313404361 cites W4229969104 @default.
- W4313404361 cites W4283584740 @default.
- W4313404361 cites W4285139979 @default.
- W4313404361 cites W4286009312 @default.
- W4313404361 cites W4297541822 @default.
- W4313404361 cites W820533651 @default.
- W4313404361 cites W863780956 @default.
- W4313404361 doi "https://doi.org/10.3390/app122413010" @default.
- W4313404361 hasPublicationYear "2022" @default.
- W4313404361 type Work @default.
- W4313404361 citedByCount "2" @default.
- W4313404361 countsByYear W43134043612023 @default.
- W4313404361 crossrefType "journal-article" @default.
- W4313404361 hasAuthorship W4313404361A5011051478 @default.
- W4313404361 hasAuthorship W4313404361A5038958143 @default.
- W4313404361 hasAuthorship W4313404361A5039737834 @default.
- W4313404361 hasAuthorship W4313404361A5040221642 @default.
- W4313404361 hasAuthorship W4313404361A5043459440 @default.
- W4313404361 hasAuthorship W4313404361A5065087041 @default.